Natural selection for adaptation (7)

Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome 8/31/21 was reported as: High virus count in the lungs drives COVID-19 deaths 8/31/21 …the study revealed that those who died had on average 50 percent lower production of a type of immune chemical that targets the coronavirus compared Natural selection for adaptation (7)

Lewis Thomas (revisited): 90K (2)

For Alfred Russel Wallace, Natural Selection Opened the Door to Teleology 8/14/18 While natural selection was Darwin’s naturalistic drive train, Wallace found that natural selection opened the door to teleology. Where utility failed, teleology entered. The exaggerated forms that Wallace alluded to in his 1856 essay on the orangutan and the wonderful colors and plumage Lewis Thomas (revisited): 90K (2)

Nutrient-dependent trophic analogs (2)

Nutrient-dependent trophic analogs The claim that Microbes are trophic analogs of animals has not yet been placed into the context of RNA-mediated events that link amino acid substitutions to cell type differentiation in all individuals of all living genera over-the-weekend. See, for example:  Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system Nutrient-dependent trophic analogs (2)

A two-faced protein enables RNA-mediated DNA repair (4)

See also: A two-faced protein enables RNA-mediated DNA repair (3) The importance of DNA repair to heritability cannot be understated. Theorists who think in terms of mutations and evolution are biologically uninformed and may never have learned anything about DNA repair. Serious scientists are overloaded with information and are not likely to try to explain A two-faced protein enables RNA-mediated DNA repair (4)


Can You Think Yourself Into a Different Person? Excerpt 1) Those who over-evangelise emerging disciplines like neuroplasticity or epigenetics can sometimes be guilty of talking as if the influence of our genes no longer matters. Excerpt 2) Of course, it’s our malleable brains that have moulded themselves to these rhythms. See also: Nature and nurture: Neuroplasticity

Models are not theories (1)

Cells or Animals: Which model is better? Excerpt: …animal models allow testing on intact physiological systems of many cell types simultaneously. Excerpt:  …it is important to note that human and rodent physiology is not identical, and even sophisticated animal models can have shortcomings. My comment: For comparison to neo-Darwinian theories, it is more important to Models are not theories (1)

RNA central and

What are lncRNAs? Excerpt:  There are many specialized lncRNA databases, which are organized and centralized through RNA central. lncRNAs can be transcribed as whole or partial natural antisense transcripts (NAT) to coding genes, or located between genes or within introns. Some lncRNAs originate from pseudogenes (Milligan & Lipovich, 2015). lncRNAs may be classified into different RNA central and