Ecological laws: what would they be and why would they matter? Abstract excerpt: … I argue, the existence of ecological laws would make ecological explanations irreducible to even the most complete possible physical explanations of the same phenomena. Ecological laws would make ecology genuinely autonomous from physics. My comment: This is a fool’s argument. Serious … Ecological law, cooperation, and DNA repair
The number π is a mathematical constant. It is the ratio of a circle’s circumference to its diameter, commonly approximated as 3.14159. π (pi) is an irrational number found in the formulas of many different branches of science, such as trigonometry, geometry, cosmology, number theory, statistics, fractals, thermodynamics, mechanics and electromagnetism. Apparently, pi was found hiding … Finding peace and π in the light of H bond energy (2)
The Cost of Protein Production The cost of protein production is commonly attributed to protein translation (Andrews and Hegeman, 1976, Emilsson and Kurland, 1990, Kurland, 1992, Marr, 1991, Molin et al., 1974, Scott and Hwa, 2011, Scott et al., 2010, Vind et al., 1993). A major fraction of the cellular GTP pool is used for … RNA-mediated theory killers (6) (7) (8) (9) (10)
Nutrient-dependent trophic analogs The claim that Microbes are trophic analogs of animals has not yet been placed into the context of RNA-mediated events that link amino acid substitutions to cell type differentiation in all individuals of all living genera over-the-weekend. See, for example: Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system … Nutrient-dependent trophic analogs (2)
See also: A two-faced protein enables RNA-mediated DNA repair (3) The importance of DNA repair to heritability cannot be understated. Theorists who think in terms of mutations and evolution are biologically uninformed and may never have learned anything about DNA repair. Serious scientists are overloaded with information and are not likely to try to explain … A two-faced protein enables RNA-mediated DNA repair (4)
Can You Think Yourself Into a Different Person? Excerpt 1) Those who over-evangelise emerging disciplines like neuroplasticity or epigenetics can sometimes be guilty of talking as if the influence of our genes no longer matters. Excerpt 2) Of course, it’s our malleable brains that have moulded themselves to these rhythms. See also: Nature and nurture: … Neuroplasticity
Cells or Animals: Which model is better? Excerpt: …animal models allow testing on intact physiological systems of many cell types simultaneously. Excerpt: …it is important to note that human and rodent physiology is not identical, and even sophisticated animal models can have shortcomings. My comment: For comparison to neo-Darwinian theories, it is more important to … Models are not theories (1)
What are lncRNAs? Excerpt: There are many specialized lncRNA databases, which are organized and centralized through RNA central. lncRNAs can be transcribed as whole or partial natural antisense transcripts (NAT) to coding genes, or located between genes or within introns. Some lncRNAs originate from pseudogenes (Milligan & Lipovich, 2015). lncRNAs may be classified into different … RNA central and RNA-mediated.com
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression Excerpt: “…glucose consumption by tumors metabolically restricts T cells, leading to their dampened mTOR activity, glycolytic capacity, and IFN-γ production, thereby allowing tumor progression.” My comment: Does anyone know the difference between 1) a tumor that eats glucose and 2) viruses that steal … Metabolic competition and cancer
Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity Excerpt: …it was hypothesized that hsf-1 regulates the aging process by modulating chaperone network components to directly influence the folding state of the proteome ( Morimoto, 2008). Our data suggest an alternate method by which hsf-1 can regulate the aging process. In this model, hsf-1 activates … Thermotolerance and Longevity
