Top-down causation

microRNA-mediated cures (2)

If you find a recently published article that does not link “How microRNAs control cell division, differentiation and death” (2005) to healthy longevity instead of virus-driven diseases, please share it for comparison to “Advances in Genetics: Chapter One – miRNA, Development and Disease (2012) and Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors (3/15/12). Neo-Darwinian theorists and Big Bang cosmologists desparately need experimental evidence of energy-dependent top-down causation to support their stupid theories, and…

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microRNA-mediated replication timing (4)

See first: microRNA-mediated replication timing (1) 6/17/21 microRNA-mediated replication timing (2) 6/27/21 microRNA-mediated replication timing (3) 6/29/21 Non-B DNA: a major contributor to small- and large-scale variation in nucleotide substitution frequencies across the genome 1/15/21 was reported on 6/29/21 as Study provides first genome-wide evidence for functional importance of unusual DNA structures Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called c (G4s) show signs that they are preserved by natural selection. The…

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God’s protection from SARS COV-2 and other viruses (1)

Light-activated “Peptide synthesis at the origin of life” links epigenetic effects on protonated RNA interference to God’s protection from virus-mediated alterations in microRNAs that enhance virus replication. See for instance: Micro-RNAs in the regulation of immune response against SARS COV-2 and other viral infections 12/2/20 Viral replication was linked to all pathology in Virus-mediated archaeal hecatomb in the deep seafloor. 10/12/16 God’s Creation of hydrogen was linked to all biophysically constrained biodiversity in Eukaryotic plankton diversity in the sunlit ocean…

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Natural models inspire future therapeutics (2)

Summary: Food odors and pheromones biophysically constrain viral latency, and an effective treatment for all neurodegenerative diseases was proposed in this 2011 patent application “Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis“ See for comparison: Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. The post- transcriptionally regulatory network of this cluster showed enrichment of key cancer-related biological processes such as cell adhesion and migration. Also, there was…

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The concept of a species (2)

The science of peaceful coexistence among members of the same species and human populations that are vilified starts with an understanding of the birds and the bees, which seems to be beyond the ability of neo-Darwinian theorists and Big Bang cosmologists to grasp. See for comparison: Birds from different species recognize each other and cooperate Article excerpt 1): Australian fairy-wrens not only recognize individual birds from other species, but also form long-term partnerships that help them forage and defend their…

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Laws of biology vs no laws of physics

There Are No Laws of Physics. There’s Only the Landscape In Einstein’s view, if we probed the essence of physics deeply enough, there would be one and only one way in which all the components — matter, radiation, forces, space and time — would fit together to make reality work, just as the gears, springs, dials and wheels of a mechanical clock uniquely combine to keep time. Reported as:  Physicist concludes there are no laws of physics It was June…

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Biologically uninformed science idiot: Self-defense (2)

Summary: “Construction of automata” is the operative phrase. But you must be willing to believe that the automata create themselves outside the context of the creation of sunlight and light-activated endogenous substrates in all cell types of all living genera. Causation, constructors and codes A formal definition of codes in general, and organic codes in particular, allows the relational diagram to be extended so as to capture this translation of formal cause into process. The extended relational diagram is used…

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The tipping point (revisited): 73,000 publications

Summary: The Bill and Melinda Gates Foundation appears to be funding misrepresentations of what serious scientists know about biophysically constrained viral latency, as if no one knew that the effect of virus-driven energy theft in a computer processing unit (CPU) is the same as the effect of bacteriophages on the human brain. The countdown that led scientific creationists in South Korea to force the denuclearization of North Korea started 2 years ago (today). 5, 4, 3, 2, 1 Predicting microRNA-disease…

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An evolutionary theory killer

MicroRNA-mediated denuclearization (6)

Summary: The EDAR V370A isoform links one quantized energy-dependent base pair change from changes in ultraviolet light (UV) exposure to fixation of one amino acid substitution. The substitution differentiates the cell types of mice and humans in the context of a mouse-to-human model of nutritional epigenetics and microRNA-mediated denuclearization in North Korea. Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk …a genetically isolated population living in this environment…

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Sympatric Speciation vs pseudosceintific nonsense (4)

The energy-dependent creation of ATP synthase and the energy-dependent creation of the microRNA repertoire have now been linked to biophysically constrained RNA-mediated sympatric speciation via the innate immune system in species from Axolotyls to A. davidianus infected with ranavirus. MicroRNA repertoire and comparative analysis of Andrias davidianus infected with ranavirus using deep sequencing MicroRNA mediated host-pathogen interactions are important in antiviral defense. See: Meet the creature that can regenerate its brain and resist cancer. (video) Identification and characterization of the…

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