Top-down causation

RNA-mediated silencing (5)

March 23, 2022
James Kohl
Adaptations, biophotonics, Ecology, Light Energy, Model Organisms, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
One Comment

See: RNA-mediated silencing (4)  Photostimulation provides an alternative to medication Those who promote the pharmacidal agenda, the racism agenda, and the LGBTQ-pedophile agenda have two things in common. 1) They refuse to link God’s Creation of energy as information from His Creation of sunlight and humidity to pH-dependent biophysically constrained viral latency across kingdoms via the physiology of reproduction and Biblical Genesis. 2) Until the APA apology for racism on 10/29/21, no other pseudoscientists ever apologized for their overwhelming ignorance of…

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RNAi 2002 to AI 2021 (9)

January 5, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed
No Comments

Things We’ve Never Seen: The James Webb Space Telescope Explores the Cosmos 12/23/21 Theorists live for the days that force them to revise their theories. When that day comes, they change their definitions to make others think that not all theorists are losers. This program is part of a series, supported by the John Templeton Foundation. The “Foundation” has no basis in the reality of facts that led intelligent serious scientists to make claims about Visualizing a protonated RNA state…

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microRNA-mediated cures (2)

December 2, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Neuronal Plasticity, Physics, replication timing, RNA editing, RNA interference, RNA–Mediated Epigenetic Heredity, What's in the News
One Comment

If you find a recently published article that does not link “How microRNAs control cell division, differentiation and death” (2005) to healthy longevity instead of virus-driven diseases, please share it for comparison to “Advances in Genetics: Chapter One – miRNA, Development and Disease (2012) and Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors (3/15/12). Neo-Darwinian theorists and Big Bang cosmologists desparately need experimental evidence of energy-dependent top-down causation to support their stupid theories, and…

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microRNA-mediated replication timing (4)

July 1, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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See first: microRNA-mediated replication timing (1) 6/17/21 microRNA-mediated replication timing (2) 6/27/21 microRNA-mediated replication timing (3) 6/29/21 Non-B DNA: a major contributor to small- and large-scale variation in nucleotide substitution frequencies across the genome 1/15/21 was reported on 6/29/21 as Study provides first genome-wide evidence for functional importance of unusual DNA structures Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called c (G4s) show signs that they are preserved by natural selection. The…

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God’s protection from SARS COV-2 and other viruses (1)

December 8, 2020
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA interference
No Comments

Light-activated “Peptide synthesis at the origin of life” links epigenetic effects on protonated RNA interference to God’s protection from virus-mediated alterations in microRNAs that enhance virus replication. See for instance: Micro-RNAs in the regulation of immune response against SARS COV-2 and other viral infections 12/2/20 Viral replication was linked to all pathology in Virus-mediated archaeal hecatomb in the deep seafloor. 10/12/16 God’s Creation of hydrogen was linked to all biophysically constrained biodiversity in Eukaryotic plankton diversity in the sunlit ocean…

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Natural models inspire future therapeutics (2)

June 24, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Summary: Food odors and pheromones biophysically constrain viral latency, and an effective treatment for all neurodegenerative diseases was proposed in this 2011 patent application “Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis“ See for comparison: Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. The post- transcriptionally regulatory network of this cluster showed enrichment of key cancer-related biological processes such as cell adhesion and migration. Also, there was…

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The concept of a species (2)

June 12, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, RNA Directed
No Comments

The science of peaceful coexistence among members of the same species and human populations that are vilified starts with an understanding of the birds and the bees, which seems to be beyond the ability of neo-Darwinian theorists and Big Bang cosmologists to grasp. See for comparison: Birds from different species recognize each other and cooperate Article excerpt 1): Australian fairy-wrens not only recognize individual birds from other species, but also form long-term partnerships that help them forage and defend their…

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Laws of biology vs no laws of physics

June 9, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
No Comments

There Are No Laws of Physics. There’s Only the Landscape In Einstein’s view, if we probed the essence of physics deeply enough, there would be one and only one way in which all the components — matter, radiation, forces, space and time — would fit together to make reality work, just as the gears, springs, dials and wheels of a mechanical clock uniquely combine to keep time. Reported as:  Physicist concludes there are no laws of physics It was June…

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Biologically uninformed science idiot: Self-defense (2)

June 2, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA–Mediated Epigenetic Heredity, Subatomic
No Comments

Summary: “Construction of automata” is the operative phrase. But you must be willing to believe that the automata create themselves outside the context of the creation of sunlight and light-activated endogenous substrates in all cell types of all living genera. Causation, constructors and codes A formal definition of codes in general, and organic codes in particular, allows the relational diagram to be extended so as to capture this translation of formal cause into process. The extended relational diagram is used…

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The tipping point (revisited): 73,000 publications

May 16, 2018
James Kohl
Adaptations, Autophagy, Cytosis, Diseases & Disorders, Ecology
2 Comments

Summary: The Bill and Melinda Gates Foundation appears to be funding misrepresentations of what serious scientists know about biophysically constrained viral latency, as if no one knew that the effect of virus-driven energy theft in a computer processing unit (CPU) is the same as the effect of bacteriophages on the human brain. The countdown that led scientific creationists in South Korea to force the denuclearization of North Korea started 2 years ago (today). 5, 4, 3, 2, 1 Predicting microRNA-disease…

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