tree of life

Codon optimality vs systemic fraud (3)

A system of fraud exists that fails to link natural selection for energy-dependent codon optimality to The Association between Single Nucleotide Polymorphisms, including miR-499a Genetic Variants, and Dyslipidemia in Subjects Treated with Pharmacological or Phytochemical Lipid-Lowering Agents 5/17/22 This article belongs to the Special Issue Molecular Effects of Phytochemicals on Cholesterol Metabolism Genes Collectively, everything Codon optimality vs systemic fraud (3)

Mechanisms of stress: from genes to cancer

Biophysically constrained nutrient-dependent thermodynamic cycles of protein biosynthesis and degradation link the epigenetic landscape to the physical landscape of DNA in all living genera. Genomic stability arises in the context of a fine-tuned balance of viral microRNAs and nutrient-dependent microRNAs.  RNA-mediated gene duplication and RNA-mediated amino acid substitutions stabilize organized genomes. Nutrient-dependent microRNAs are linked Mechanisms of stress: from genes to cancer