Light, behavior and autophagy, a gender-specific risk factor

Structure of photosystem II and substrate binding at room temperature Excerpt: PS II, a membrane-bound multi-subunit pigment protein complex, couples the one-electron photochemistry at the reaction centre with the four-electron redox chemistry of water oxidation at the Mn4CaO5 cluster in the oxygen-evolving complex (OEC). New, detailed snapshots capture photosynthesis at room temperature The living machinery Light, behavior and autophagy, a gender-specific risk factor

Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)

See also Light ‘drives’ adaptation; nothing ‘drives’ evolution (2) 100 feet below the surface bioluminescent organisms are the dominant light source, study shows Excerpt: “Luminescent marine organisms each have a unique light signature. By looking at the time series light generated by a flash within the instrument, we were able to determine who was there Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)

The last RNA-mediated theory killer (2)

Autophagy (epigenetically effected by nutrient-energy and controlled by the physiology of reproduction) See for comparison: Virus-driven energy theft and epigenetically-effected autophagy Selleck Chem product use citations Excerpts: Pathological axonal death through a MAPK cascade that triggers a local energy deficit. Inhibitors of cellular kinases with broad-spectrum antiviral activity for hemorrhagic fever viruses. A causal link The last RNA-mediated theory killer (2)

Base pairs, olfaction and RNA thermometers

RNA thermometer controls temperature-dependent virulence factor expression in Vibrio cholerae (2014) Excerpt: The stem-loop can be stabilized by strengthening the base pairing between the fourU element and SD sequence through the substitution of G-C base pairs, and this results in an elevated melting temperature (10). Conclusion: RNA thermometers represent a simple yet elegant mechanism for Base pairs, olfaction and RNA thermometers

Hydrogen-atom energy in DNA base pairs

See also: Consciousness is simply food rearranged Role of Double Hydrogen Atom Transfer Reactions in Atmospheric Chemistry Abstract excerpt:  Hydrogen atom transfer (HAT) reactions are ubiquitous and play a crucial role in chemistries occurring in the atmosphere, biology, and industry. My comment: The link from physics to chemistry and the conserved molecular mechanisms of biologically-based Hydrogen-atom energy in DNA base pairs

Antithetical conclusions (4)

Evidence for sex-specific genetic architectures across a spectrum of human complex traits …will need to disentangle whether sex genetic heterogeneity may arise as a consequence of interactions with genetic loci located on the sex chromosomes, differences in gene control due to differences in the sex-specific cellular environment, or more general differences in environmental exposures between Antithetical conclusions (4)

Antithetical conclusions (3)

Local modulation of chemoattractant concentrations by single cells: dissection using a bulk-surface computational model This is part of the Theme issue ‘Coupling geometric partial differential equations with physics for cell morphology, motility and pattern formation’ Excerpt: “The computed ligand concentration and receptor occupancy on the evolving cell membrane are shown in figure 5.” Conclusion: “…the Antithetical conclusions (3)

Non-random pheromone-controlled cell type differentiation

Experience-Dependent Plasticity Drives Individual Differences in Pheromone-Sensing Neurons Aug 17, 2016   •Individual differences in cell types are not random •Sex differences in pheromone-sensing neurons are controlled by experience •Changes in specific cell types are governed via “use it and lose it” plasticity •Targeting plasticity to specific cell types changes animal behavior This was reported Non-random pheromone-controlled cell type differentiation

Did “Nature” kill Steve Jobs? (2)

See also: Did “Nature” kill Steve Jobs? In my model of biophysically constrained energy-dependent protein folding chemistry and RNA-mediated cell type differentiation, the nutrient-dependent pheromone-controlled physiology of reproduction links the innate immune system to supercoiled DNA, which protects all organized genomes from virus-driven entropy. For comparison to my model, see: Evolution 2016 Videos (Indexed) Youtube Did “Nature” kill Steve Jobs? (2)

Energy-dependent biodiversity (2)

This will be my next post to the “Creationism” FB group, where biologically uninformed antagonists have been attacking me on all my other posts or my comments on the posts of others. See, for example: In a series of four presentations during three online conferences: “Neuroscience” “Molecular Diagnostics” “Genetics and Genomics,” I linked Einstein’s math Energy-dependent biodiversity (2)