UV-Induced Charge Transfer States in DNA

Virus-driven genome engineering causes cancer?

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response Inhibition of p53 prevents the damage response and increases the rate of homologous recombination… In the 1990’s, Abcam researchers discovered the cell death gene. Now see: Mechanisms of Recombination conference See also: P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells We demonstrated the toxic response is tp53-dependent and the toxic effect of tp53 severely reduces the efficiency of precise genome-engineering in hPSCs. Reported as:…

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From quantum physics to quantum souls (2)

Summary: Natural selection for food energy-dependent codon optimality links the physiology of pheromone-controlled reproduction to all biodiversity on Earth via gene splicing and energy-dependent RNA-mediated fixation of amino acid substitutions. How humans and apes are different, and why it matters (2018) …the most distinctive feature of humanity is its ability to significantly alter ecosystems. That exemplifies human idiocy. The most distinctive features of humanity are biophysically constrained by what people eat and the physiology of pheromone-controlled reproduction. See: Nothing in Biology…

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