viral endemicity

Codon optimality vs systemic fraud (5)

June 27, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Light-Controlled Recruitable Hybridization Chain Reaction on Exosome Vehicles for Highly Sensitive MicroRNA Imaging in Living Cells 6/27/22 links more than 144,000 other publications that mention miRNAs from Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 to patented therapeutic solutions that help to protect organized genomes from the virus-driven degradation of messenger RNA. See: Results of Search in PGPUB Production Database and specifically: Nutraceuticals for the prevention, inhibition, and treatment of SARS-CoV-2 and associated COVID-19 The fact that natural selection…

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Crimes against humanity (2)

June 26, 2022
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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If they continue to ignore the science, the opinions of patriots will continue to be ignored. See for comparison, the science of virus-driven disease prevention. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer (2015) and Expression change in Angiopoietin-1 underlies change in relative brain size in fish (2015) link miRNAs in exosomes to viral endemicity via Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3 (2015) and the honeybee model of Nutrient-dependent/pheromone-controlled adaptive evolution (2013) In…

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Polymathy changes society (1)

June 17, 2022
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA interference, Subatomic, Variations
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Is X-FILES relevant now… Did X-FILES predict the future? 6/9/22 (video) Science fiction author Greg Bear linked gene editing technology to the laboratory-based creation of a novel virus in his 2006 review published as “Quantico.” His claims about the existential threat were turned into a comedy routine by Jon Stewart. 6/1/07 (video) Former President Trump linked God’s Creation of sunlight and humidity to healthy longevity via KB Whaley’s polymathy when he claimed, albeit indirectly, that pH-dependent microRNA-mediated protein folding chemistry…

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Codon optimality vs systemic fraud (2)

June 9, 2022
James Kohl
Adaptations, base editing, Diseases & Disorders, Ecology, Human Pheromones, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity
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See first: Codon optimality vs systemic fraud (1) Researchers identified over 5,500 new viruses in the ocean, including a missing link in viral evolution 4/8/22 and Ocean water samples yield treasure trove of RNA virus data 4/8/22 attest to facts about the Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 that link God’s ATP-dependent Creation of RNA from RNA-peptide interactions at the origin of life to the Mapping and characterization of structural variation in 17,795…

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Codon optimality vs systemic fraud (1)

June 5, 2022
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Two summaries of neo-Darwinian evolutionary theory: Amino acid composition of proteins varies substantially between taxa and, thus, can evolve. …yeast receptors trigger activation of heterotrimeric G proteins just as mammalian receptors do, this conserved signaling pathway must have been present in the common ancestor of yeast and humans. Unless you are a biologically uninformed theorist, see first Epistemic corruption (10) Watch for my next 10-part series on Codon optimality vs systemic fraud. I will link it to the fraudulent representations…

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Epistemic corruption (1)

May 9, 2022
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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Sunlight is the best disinfectant. That claim was echoed by Elon Musk on 5/3/22. If he stops the social media censorship of facts on Twitter, the epistemic corruption may end. Epistemic Corruption, the Pharmaceutical Industry, and the Body of Medical Science 3/8/21 It is not just that there is a body of medical science perverted by industry largesse. Instead, much of the corruption of medical science via the pharmaceutical industry happens through grafting activities: Pharmaceutical companies do their own research…

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MicroRNA-mediated existential threats (10)

May 7, 2022
James Kohl
Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, RNA Directed, RNA interference
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Food energy gets sunlight into our veins (2) @CaudeHenrion &  @exosome linked the “…architecture of RNA-peptide interactions…” at the origin of life to observable and experimental evidence of God’s energy-dependent Creation via data-driven computational predictions. 5/7/22 update: CircMiMi: a stand-alone software for constructing circular RNA-microRNA-mRNA interactions across species (5/6/22) Light activated carbon fixation in cyanobacteria and microRNA-mediated protein folding chemistry link the interactions from protonated RNA interference and “…non-coding RNAs formed by pre-mRNA back-splicing…in animal/plant cells…” to regulation of all pH-dependent…

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MicroRNA-mediated existential threats (4)

April 24, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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See first:  MicroRNA-mediated existential threats (3) On 4/19/22 I posed this question on Twitter. Why do people believe stupid theories about the evolution of amino acid composition in proteins, which requires them to ignore everything known to intelligent serious scientists about how SARS-CoV-2 synthetic mRNA vaccinations altered biophysically constrained viral endemicity? 4/19/22 How can it not be perfectly clear that stupid theories about the evolution of amino acid composition in proteins ignore everything known to all intelligent serious scientists about…

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RNA-mediated silencing (8)

April 1, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Now fully complete, human genome reveals new secrets 3/31/22 reports on: A next-generation human genome sequence 3/31/22 From telomere to telomere: The transcriptional and epigenetic state of human repeat elements 4/1/22 The complete sequence of a human genome 4/1/22 Epigenetic patterns in a complete human genome 4/1/22 Complete genomic and epigenetic maps of human centromeres 4/1/22 The articles and the reporting obfuscate the fact that God’s Creation of energy-as-information links sunlight and humidity to His Creation of all biodiversity on…

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RNA-mediated silencing (6)

March 23, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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See first RNA-mediated silencing (5) The AVONET database contains 11 morphological traits, such as beak shape and wing length, for 90,020 individual birds from 181 countries. It fails to link differences in uni-parental or bi-parental feeding from fixation of amino acid substitutions to the color of white-throated sparrows, which was linked to ethnic difference in skin color via chromosomal rearrangements across kingdoms via Estrogen receptor α polymorphism in a species with alternative behavioral phenotypes  1/13/14 The failure to link food…

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