viral microRNA

Pathology: Eating and breathing viruses

RNA viruses can hijack vertebrate microRNAs [miRNAs] to suppress innate immunity Excerpt: The extent of sequence complementary between the miRNA and mRNA leads to control of mRNA-encoded polypeptide levels by either a block in translation, degradation of the mRNA, or both5, 6. For RNA viruses, limited evidence exists for host miRNAs binding to viral RNAs Pathology: Eating and breathing viruses

Exosomes and the RNA-mediated future of medicine (3)

September 11, 2015 Case Western Reserve scientists discover long-sought genetic mechanism for cancer progression Excerpt: Action of a key lncRNA different in colon cancer versus normal colon tissue My comment: In yet another ridiculous misrepresentation of all that is currently known about how the epigenetic landscape is linked to the physical landscape of DNA in Exosomes and the RNA-mediated future of medicine (3)

DNA Methylation and organized genomes

This open access review that is linked from the title (below) will appear in the next issue of Int J Biol Sci 2015; 11(5):604-617. doi:10.7150/ijbs.11218 It is a excellent, albeit incomplete, review of how nutrient-dependent RNA-directed DNA methylation and RNA-mediated amino acid substitutions link the epigenetic landscape to the physical landscape of DNA via the DNA Methylation and organized genomes