viral microRNAs

The MicroRNAome Strikes Back: A Sokalian hoax (3)

January 24, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity
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One way to recognize a Sokalian hoax is to determine whether the claims can be linked from gravity or from the speed of light on contact with water to feedback loops that biophysically constrain viral latency and all biodiversity in all living genera. See: Feedback loops link odor and pheromone signaling with reproduction See for comparison: Chiromagnetic nanoparticles and gels Reported as: Nanoparticle gel controls twisted light with magnetism The trick, the researchers found, was to twist the nanoparticles themselves by coating them…

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Lethal virus kills 5 billion people?

The “walking fish” walks straight from quantum physics to quantum souls (5)

January 4, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Diseases & Disorders, Ecology, RNA Directed
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Evolutionary determinants of genome-wide nucleotide composition January 1, 2018 1) They place their thoughts about mutation rates into the context of compatibility with mutational spectra. 2)They claim the mutation rate can be linked to mutational spectra that may be free to wander across evolutionary time. 3) They ignore facts that link the energy-dependent maintenance of a suppressed constant genome-wide deleterious rate that obviously occurs in the context of the Virus-mediated archaeal hecatomb in the deep seafloor 4) They eliminate the…

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Electron cloud superimposed on the yin yang symbol

The “walking fish” walks straight from quantum physics to quantum souls (3)

January 3, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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The molecular dynamics of the hydrophobic amino acid, valine, link the anti-entropic virucidal energy of sunlight from the Second Law of Thermodynamics to the energy-dependent and temperature-dependent orientational dynamics of the structure of water via methylation and acetylation in the C and N terminus, respectively. The quantized energy of sunlight must be linked from energy as information to energy-dependent methylation and acetylation to all biodiversity via the effect of the energy on contact with water and the physiology of pheromone-controlled…

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For God and Country

Faith in evolution: Paleontology as a molecular science

October 16, 2017
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic
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Keeping the faith For the last 20 years, Mary Schweitzer, a paleontologist at North Carolina State University in Raleigh, has amassed a wealth of evidence that she’s isolated protein fragments from dinosaurs as much as 80 million years old. That bucks the conventional wisdom among paleontologists who argue that proteins, which are made of chains of amino acids, can’t survive more than 1 million years or so. So far, no group other than Schweitzer and her collaborators has managed to…

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Energy-dependent physical and biophysical constraints (6)

July 27, 2017
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, Variations
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Conclusion: Like Richard Dawkins, Magnus S. Magnusson is a pseudoscientist. A light-induced change in an endogenous substrate found in all cell types of all living genera links femtosecond blasts of UV light from the de novo creation of the innate immune system to RNA-mediated DNA repair in species from microbes to humans. The theft of quantized energy by viruses has been linked to all pathology. The speed at which quantum decoherence occurs makes it difficult for virus-driven energy theft to…

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God’s shrinking role in salvation (2)

June 14, 2017
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Physics, RNA Directed, Variations
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Conclusion: There is no such thing as a blind dance of atoms. Quantized energy-dependent changes link angstroms to ecosystems in all living genera via the physiology of reproduction. Serious scientists do not link “high-level cause and purposes” to anything that does not link what organisms eat from food energy to the physiology of reproduction. Only pseudoscientists claim that ideas about “emergence” are “…a remarkable synthesis across fields and levels.” See: God’s shrinking role in salvation These 6 Common Vegetables Are…

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Food energy-dependent cell type differentiation (2)

June 6, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations
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Summary: The concept of “faster-evolving DNA” regions in the context of nucleotide variation in both the 16S and 12S sequences is not consistent with any accurate representation of how the functional structure of supercoiled DNA must be linked from energy-dependent changes in angstroms to ecosystems in all living genera. Conserved molecular mechanisms link the sense of smell in bacteria from the de novo creation of olfactory receptor genes to the physiology of reproduction via the microRNA/messenger RNA balance and Feynman’s…

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Theistic evolutionists fight back and lose (2)

February 27, 2017
James Kohl
Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
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For a historical perspective on the amount of ignorance theistic evolutionists and atheists have repeatedly displayed as they ignored everything known about the energy-dependent RNA-mediated de novo creation of genes, see: The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels (1982) Thirty-five years later, there is another clear indication that theorists and atheists will never consider the fact that there must be an anti-entropic virucidal source of energy. See for example: HSP90 Shapes the Consequences of…

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Vietnam Veterans and others with glioblastoma

December 30, 2016
James Kohl
Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Model Organisms, Neuronal Plasticity, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, Variations, What's in the News
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The Agent Orange Widows Club After their husbands died of an aggressive brain cancer, the widows of Vietnam veterans have found one another as they fight the VA for benefits. See also: Vietnam Veterans with Glioblastoma Multiforme Stage 4 Brain Cancer This post was removed: Targeting NF-κB in glioblastoma: A therapeutic approach This is the level of complexity that the VA needs to understand and link to the treatment of this aggressive cancer, which is obviously caused by virus-driven energy theft.…

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Theories vs facts about polycombic adaptation

December 6, 2016
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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See: Demoncrats fight polycombic ecological adaptation Exosomes as miRNA Carriers: Formation–Function–Future Important aspects will be highlighted as a take-home message (THM) at the end of each paragraph. THM: Extracellular vesicles transport miRNA in a paracrine and endocrine manner. Questions regarding the cellular options of producing either microvesicles or exosomes and their difference in miRNA composition and number are still unknown. In my 2014 invited review, the four F’s, Formation–Function–Future and Copulation were included in details about how the nutrient energy-dependent…

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