viruses

microRNA-mediated election cycles (8)

July 16, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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See first: microRNA-mediated election cycles (7) The virus-driven decrease in free energy has been linked from altered maturation of miRNAs to all pathology across kingdoms. Naturally occurring light-activated carbon fixation links miRNA biogenesis and maturation to biophysically constrained viral latency via the patent for protonated RNA interference, which is titled: RNA-Guided Human Genome Engineering The role played by feedback loops that link food odors and pheromones to reproduction has been linked to Friendship and natural selection 7/22/14 Natural selection focuses…

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Pheromones protect us from viruses (7)

March 30, 2021
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Physics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity
One Comment

It’s been more than one year since Guenther Witzany published What is Life? 3/18/20 “A new definition of life must integrate the current empirical knowledge about interactions between cells, viruses, and RNA networks to provide a better explanatory power than the twentieth century narrative.” The need for the new definition of life is consistent with my claims from “What is life when it is not protected from virus-driven entropy.” It’s been 5 years since this virtual conference presentation on 3/30/16. The…

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pH-dependent healthy longevity (2)

July 14, 2020
James Kohl
Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Physics, RNA interference
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Trump wears mask while visiting wounded soldiers, medical workers at Walter Reed hospital 7/12/20 Trump said he planned to wear a mask during the Walter Reed visit because “you’re in a hospital setting,” and “I think it’s a very appropriate thing. … I have no problem with a mask.” Use of a fast transcutaneous CO2 detector to evaluate escape hoods: the “CAPS 2000” with the inlet valves removed from the nose-cup as a test case (2012) Research showed increased CO2/hypercapnia…

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Vaccines do not control pandemics (1)

May 15, 2020
James Kohl
Adaptations, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, Subatomic
2 Comments

See: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/16/18 Compared to the G2 RotaTeq vaccine strain, 17-24 amino acid changes, specifically A87T, D96N, S213D, and S242N substitutions in G2 epitopes, were observed. Amino acid changes control pandemics. Congo: MSF Ebola vaccination begins 5/30/18 The Ebola vaccine (rVSVDG-ZEBOV-GP) is being used as part of the overall strategy to control the Ebola outbreak. There was no indication that the vaccine strategy…

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WHO’s ignorance: From roots to shoots (2)

March 24, 2020
James Kohl
Adaptations, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, Pharmacogenomics, RNA interference, What's in the News
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WHO’s ignorance: From roots to shoots (1) Amino acid substitutions within or near the active site of the viral neuraminidase (NA) may affect influenza virus fitness. See: Neuraminidase inhibitor susceptibility and neuraminidase enzyme kinetics of human influenza A and B viruses circulating in Thailand in 2010–2015  The authors cite the World Health Organization’s Summary of neuraminidase amino acid substitutions associated with reduced inhibition by neuraminidase inhibitors” The summary is available as a pdf download. See also: Viral Factors Associated With…

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Natural models inspire future therapeutics

June 22, 2018
James Kohl
Adaptations, base editing, Cytosis
One Comment

Natural models inspire future therapeutics See: Screaming viruses and Alzheimer’s (1) Screaming viruses and Cancer Screaming Viruses and Alzheimer’s (2) MicroRNA biogenesis, the microRNAome, and your brainome and Reciprocal Interactions Between Gut Microbiota and Host Social Behavior We suggest that investigating these reciprocal interactions can advance our understanding of sociality, from healthy and impaired social cognition to the evolution of specific social behaviours and societal structure. There is no natural model of evolved social behavior. I suggest that all theorists…

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Nutrient-dependent pheromone-controlled feedback loops

May 3, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: The link from positive selection to one food energy-dependent base pair change and fixation of the mouse-model-to-human-specific EDAR V370A allele in populations on different continents attests to sympatric speciation at every level of examination that refutes the pseudoscientific nonsense of neo-Darwinian mutation-driven evolution. Reported on 5/3/18 as: SWAT team of immune cells found in mother’s milk  1) “There is a feedback loop,” says Yu. It’s known that some immune cells like leucocytes, another white blood cell that fights infection,…

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Is meat protein unhealthy? (2)

April 5, 2018
James Kohl
Adaptations, Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, RNA Directed
No Comments

See also: Microbiome-Grade DNA Extraction Kits …the thermal and chemical methods effectively lyse the gram-negative organisms and boost their population in the final profile, amplifying the bias. This suggests that all links from food energy-dependent de novo creation of the pheromone-controlled biophysically constrained bull sperm microRNAome have been misinterpreted in the context of virus-driven fescue toxicosis. The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression …the miRNA profile of mature ejaculated sperm may in fact…

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Is meat protein unhealthy? (1)

April 5, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, RNA Directed, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations
No Comments

Patterns of plant and animal protein intake are strongly associated with cardiovascular mortality Reported as: Meat protein is unhealthy, but protein from nuts and seeds is heart smart In the context of everything known about how the creation of anti-entropic virucidal light must be linked to all biodiversity on Earth, watch this ridiculous misrepresentation of the honeybee model organism. Food energy-dependent microRNA-mediated pheromone-controlled biophysically constrained viral latency is portrayed as if visual input was most important. Bee swarms work like…

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Light-controlled cell biology (revisited)

March 21, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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See Sci-Bay Scholar for citations and downloads of more than 3300 published works that link viruses to microRNAs Summary: …either the organized genomes of all cell types use the energy source, or viruses use the biophysically constrained energy of the cell types. No extant species can be used as an example of how the virus-driven theft of quantized energy can be linked from natural selection to the evolution of a new species. See also, with my emphasis: Light Offers New…

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