viruses

Natural models inspire future therapeutics

June 22, 2018
James Kohl
Adaptations, base editing, Cytosis
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Natural models inspire future therapeutics See: Screaming viruses and Alzheimer’s (1) Screaming viruses and Cancer Screaming Viruses and Alzheimer’s (2) MicroRNA biogenesis, the microRNAome, and your brainome and Reciprocal Interactions Between Gut Microbiota and Host Social Behavior We suggest that investigating these reciprocal interactions can advance our understanding of sociality, from healthy and impaired social cognition to the evolution of specific social behaviours and societal structure. There is no natural model of evolved social behavior. I suggest that all theorists…

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Nutrient-dependent pheromone-controlled feedback loops

May 3, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: The link from positive selection to one food energy-dependent base pair change and fixation of the mouse-model-to-human-specific EDAR V370A allele in populations on different continents attests to sympatric speciation at every level of examination that refutes the pseudoscientific nonsense of neo-Darwinian mutation-driven evolution. Reported on 5/3/18 as: SWAT team of immune cells found in mother’s milk  1) “There is a feedback loop,” says Yu. It’s known that some immune cells like leucocytes, another white blood cell that fights infection,…

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Is meat protein unhealthy? (2)

April 5, 2018
James Kohl
Adaptations, Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, RNA Directed
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See also: Microbiome-Grade DNA Extraction Kits …the thermal and chemical methods effectively lyse the gram-negative organisms and boost their population in the final profile, amplifying the bias. This suggests that all links from food energy-dependent de novo creation of the pheromone-controlled biophysically constrained bull sperm microRNAome have been misinterpreted in the context of virus-driven fescue toxicosis. The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression …the miRNA profile of mature ejaculated sperm may in fact…

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Is meat protein unhealthy? (1)

April 5, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, RNA Directed, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations
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Patterns of plant and animal protein intake are strongly associated with cardiovascular mortality Reported as: Meat protein is unhealthy, but protein from nuts and seeds is heart smart In the context of everything known about how the creation of anti-entropic virucidal light must be linked to all biodiversity on Earth, watch this ridiculous misrepresentation of the honeybee model organism. Food energy-dependent microRNA-mediated pheromone-controlled biophysically constrained viral latency is portrayed as if visual input was most important. Bee swarms work like…

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Light-controlled cell biology (revisited)

March 21, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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See Sci-Bay Scholar for citations and downloads of more than 3300 published works that link viruses to microRNAs Summary: …either the organized genomes of all cell types use the energy source, or viruses use the biophysically constrained energy of the cell types. No extant species can be used as an example of how the virus-driven theft of quantized energy can be linked from natural selection to the evolution of a new species. See also, with my emphasis: Light Offers New…

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Ecological adaptation: A new definition of heredity (2)

March 7, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Diseases & Disorders, Ecology, RNA Directed
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The 1902 definition of mutation by Hugo de vries can again be placed into the context of facts about energy-dependent RNA-mediated cell type differentiation and healthy longevity before anyone else attempts to redefine heredity. Hopefully, that will be done before anyone else from the CDC goes missing. The threat to thos who understands how top-down causation is linked to the transgenerational epigenetic inheritance by cell survival is severe because they have linked virus-driven energy theft from mutations to the death…

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George Church refutes theistic evolution (4)

February 15, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference
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See: George Church refutes theistic evolution (February 9, 2017) See also: Energy as information and constrained endogenous RNA interference (February 15, 2017) Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy. The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements. The rearrangements link energy-dependent fixed amino acid…

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An evolutionary theory killer

Conceptual critique: Innateness vs the death gene (2)

February 14, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Excerpt: Martie Haselton notes “…there’s a hidden adaptive intelligence that has been shaped over eons. Martie Haselton places that ecological adaptation into the context of the claim that “…our bodies are designed to fight off invaders, whether they take the form of a cold virus… (p 73.) and she mentions the link from the designer to one theory about menstruation: “female bleeding serves to flush out “bad” sperm that may carry bacteria, viruses and other pathogens.” (p. 84) See also:…

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The tipping point (revisted): 69,000 publications

January 20, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed, What's in the News
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See first: The tipping point (revisited): 68,000 publications December 21, 2017 On December 24, 2017, I started a “tweet” series on Twitter, which was designed to test the response to accurate information about RNA-mediated energy-dependent biophysically constrained viral latency. Nearly 80,000 impressions have led to few engagements and virtually no discussion during a time when almost 1000 additional published works have been indexed on the PubMed database. In my January 20, 2018 PubMed search for term “microRNA,” among nearly 69,000 results,…

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For God and Country

The “walking fish” walks straight from quantum physics to quantum souls

December 31, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Happy New Year! In 2018, serious scientists are prepared to help you prevent or effectively treat all pathology. We have nearly stopped the pseudoscientific nonsense touted by theorists — although some of them didn’t get the memo from 1968, which is when Frohlich published: Long-range coherence and energy storage in biological systems. He linked certain processes in living systems from the creation of energy to hydrogen bonds in cell membranes and to dipolar oscillations that link the creation of the…

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