Zika virus

Happy Darwin Day (2017)

My series of blog posts about the refutation of theistic evolution by George Church led him to contact me via email. He asked why he would get credit for or against the refutations He claimed he was trained in quantum physics. He claimed that he has authored peer reviewed papers on protein folding, biodiversity, supercoiling, etc. He wanted to know more but did not know enough about my target audience to realize why I included information about the viral hecatomb.…

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Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.

Nothing known to serious scientists links anything except energy-dependent changes in chirality to autophagy and biodiversity via RNA-mediated amino acid substitutions that differentiate all cell types in all living genera. That fact forces pseudoscientists to invent new terms to confuse the biologically uninformed masses who were taught to believe in the neo-Darwinian pseudoscientific nonsense of mutation-driven evolution. Autophagy in the liver: functions in health and disease  See the section: Regulation of autophagy by amino acids See for comparison: From Fertilization…

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Energy-dependent coulombic, autophagic, polycombic healthy longevity

Mitophagy is the selective degradation of mitochondria by autophagy. See also this excerpt: Disorders in energy creation by mitochondria can cause cellular degeneration… Mitochondria do not create energy.  They link the creation of the sun’s anti-entropic virucidal energy to RNA-mediated cell type differentiation via biophysically constrained DNA repair. Energy-dependent autophagy links mitophagy to supercoiled DNA via the innate immune system and RNA-mediated repair of damaged DNA. Repair is nutrient-energy dependent. Separating mitophagy from autophagy is one way to prevent people…

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Did evolution autophosphorylate your kinases? (3)

Did evolution autophosphorylate your kinases? (1) Did evolution autophosphorylate your kinases? (2) See also: N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection Reported as: Chemical tags affect ability of RNA viruses to infect cells Dynamics of Human and Viral RNA Methylation during Zika Virus Infection Reported as:  Zika virus infection alters human and viral RNA My comment: Virus-driven hecatombic evolution of all pathology is linked from the failure of energy-dependent phosphorylation to biophysically constrain the RNA-mediated damage to DNA via…

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The natural success of RNAi and failed treatment

see my other blog posts on m6A Dynamics of Human and Viral RNA Methylation during Zika Virus Infection Excerpt: …ZIKV infection alters m6A location in mRNAs, methylation motifs, and target genes modified by methyltransferases. Our results identify a mechanism by which ZIKV interacts with and alters host cell functions. Reported as: Zika virus infection alters human and viral RNA Excerpt: When Zika virus infects a human cell, Rana’s team found, the cell modifies viral RNA with m6A as a means…

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Light ‘drives’ adaptation; nothing ‘drives’ evolution

Codon identity regulates mRNA stability and translation efficiency during the maternal‐to‐zygotic transition Abstract: Cellular transitions require dramatic changes in gene expression that are supported by regulated mRNA decay and new transcription. The maternal-to-zygotic transition is a conserved developmental progression during which thousands of maternal mRNAs are cleared by post-transcriptional mechanisms. Although some maternal mRNAs are targeted for degradation by microRNAs, this pathway does not fully explain mRNA clearance. We investigated how codon identity and translation affect mRNA stability during development…

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Virus altered thermodynamic stability

Mechanisms of Zika Virus Infection and Neuropathogenesis and Flavivirus infection requires specific host genes Excerpt: The researchers identified 9 genes that… are associated with the cell’s endoplasmic reticulum, where viral translation, replication, and assembly of viral particles takes place. Six of the genes also reduced infection of Zika, dengue, Japanese encephalitis, and yellow fever viruses when removed from human cells. Most showed similar effects when absent from insect cells tested for West Nile and dengue virus infections. My comment: They…

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Energy-dependent RNA methylation (7)

“…viral latency is responsible for life-long pathogenesis and mortality risk…” – Lieberman (2016) My comment: Energy-dependent RNA-mediated amino acid substitutions are responsible for life-long healthy longevity and decreased mortality risk. See for comparison: How cancer was created by evolution Excerpt 1) But even though it is evolutionary processes that have made cancer such a problem, it is also evolutionary thinking that is now leading to pioneering treatments that could stack the odds against cancer and in favour of our health.…

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Energy-dependent RNA methylation (1)

“How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy?” — Roger Penrose “We know, for instance, when we eat food nucleic acids can get into our cells. Also, there is a theory that our cells in the body keep sending out nucleic acids and one theory has it that it seems to correct the mistakes that other cells have suffered…

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War Games: False Flag Terrorism

Sirius Cyantis (aka Sean Ovis) takes my claims about virus-driven energy theft and pathology outside the context of creationism.  Using his assumed name, he places them into the context of support for evolution. That’s an example of what happens on the “False Flag” Creationism FB group. In the context of combating evolution to fight disease, the war games become more interesting. Most people in False Flag groups do not know who they are fighting against. In the end it won’t…

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