See Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems
Click on the numbered citations, which link
1) Darwin CR (1909–14) Origin of species (Vol. 11). New York: P.F. Collier & Son. to 160) Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki S, et al. (2013) Identifying recent adaptations in large-scale genomic data. Cell 152: 703-713.
If you are not able to accept the fact that food energy is linked to species-wide ecological adaptations and mutations are linked to all pathology, keep touting pseudoscientific nonsense until all your claims are dismissed by serious scientists and everyone else with common sense.
See also: Kamberov YG, Wang S, Tan J, Gerbault P, Wark A, et al. (2013) Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell 152: 691-702.
The EDAR variant, V370A has since been linked to Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk
The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection…
That claim links the mouse-to-human model of natural selection for quantized energy-dependent codon optimality to fixation of the amino acid substitutions that stabilize the morphological and behavioral phenotypes of all living genera. The substitutions protect individuals of all species from the virus-driven degradation of messenger RNA, which all serious scientists have linked to all pathology.
That fact makes it unlikely that human populations in North and East Asian and New World populations exemplify the claims of biologically uninformed neo-Darwinian theorists. For some reason, the theorists still seem to believe that mutations led to the evolution of the similarities and the differences in human populations. No experimental evidence of biophysically constrained top-down causation has ever been used to support their ridiculous claims that link mutations to the simultaneous evolution of different human populations in North and East Asian and New World populations.
Clearly, ecological variation is the link to nutrient-dependent pheromone-controlled ecological adaptations in different human populations in North and East Asian and New World populations. In this case, the EDAR V370A allele exemplifies environmental section for fixation of one quantized energy-dependent biophysically constrained RNA-mediated amino acid substitution.
See for comparison: Nothing in Biology Makes Any Sense Except in the Light of Evolution (1973)
…the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla.
The differences in fixation of single amino acid substitutions refute ever aspect of neo-Darwinian pseudoscientific nonsense at every level of examination in every model organism.
See also: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994)
What organisms eat biophysically constrains all epigenetic effects of food via the metabolism of food to pheromones that control the physiology of reproduction.
See also: Feedback loops link odor and pheromone signaling with reproduction (2005)