Trashing the 2nd Law
(click to enlarge)
Summary: Autophagy is the antiphage defense strategy. (December 8, 2016) Other definitions no longer apply.Experiment shows that arrow of time is a relative concept, not an absolute one Olfaction Warps Visual Time Perception Molecular recognition in olfaction QuEBS 2018: Workshop on Quantum Effects in Biological Systems Bamboo Specialists from Two Mammalian Orders (Primates, Carnivora) Share a High Number of Low-Abundance Gut Microbes Separated Since the Dinosaurs, Bamboo-Eating Lemurs, Pandas Share Common Gut Microbes
“This really underscores the role that diet plays in determining what lives in our guts – and, in turn, how these microbial ecosystems can shape the way animals live,” McKenney says.
Microbial ecosystems are food energy-dependent and the pheromone-controlled physiology of reproduction biophysically constrains viral latency. Without the pheromone-controlled physiology of food energy-dependent reproduction, bacteriophages and the virus-driven theft of quantized energy would link mutations to loss of functional structures that protect organized genomes from the degradation of messenger RNA. Everything known about cell type differentiation in all living genera has been placed into the context of links from physics and chemistry to molecular epigenetics via what is known about supercoiled DNA.
“The bamboo lemur’s evolutionary tree diverged from that of both panda species 83 million years ago – that’s 18 million years before dinosaurs went extinct,” says Erin McKenney, a postdoctoral researcher at North Carolina State University and lead author of a paper on the study. “These species are also separated by thousands of miles and the Indian Ocean. Red pandas and giant pandas aren’t closely related either, with their most recent ancestor coming 47.5 million years ago. Lemurs are primates, red pandas are related to raccoons, and pandas are related to bears.
“Yet all three species share these 48 gut microbes – more than 12 percent of the microbial types found in each species’ gut,” McKenney says. “The only common feature is their diet: all three species live almost exclusively on bamboo.”
The common feature was presented in this 2013 review: Nutrient-dependent/pheromone-controlled adaptive evolution: a model , which is a refutation of all neo-Darwinian pseudoscientific nonsense, and also a refutation of the ridiculous misrepresentations of “Big Bang” cosmologists. Those misereqpresentations led to two retractions of works published by Jack Szostak’s group in which false claims were made about non-enzymatic RNA replication.Altered responses to social chemosignals in autism spectrum disorder Study: Autism Linked with Different Reactions to Chemical Signals
“we speculate that social dysosmia may underlie part of the impaired reading of emotional cues in ASD.”
See for comparison: Global Sensory Impairment Predicts Morbidity and Mortality in Older U.S. Adults Problems with senses may predict older adults’ overall health, ability to function
Until now, no studies have examined how losing multiple senses affects older adults. To learn more, a team of researchers from the University of Chicago [including Martha McClintock] designed a study to focus on just that. Their study was published in the Journal of the American Geriatrics Society.
Problems with the senses are tractable to differences in the energy-dependent changes in base pairs that link changes in the microRNA/messenger RNA balance from RNA editing to the pheromone-controlled fixation of amino acid substitutions that stabilize the organized genomes of all living genera by protecting the organized genomes from the virus-driven degradation of messenger RNA.Structural diversity of supercoiled DNA
Reversing the thermodynamic arrow of time using quantum correlations
…standard thermodynamics presupposes the absence of initial correlations between interacting systems. We here experimentally demonstrate the reversal of the arrow of time for two initially quantum correlated spins-1/2, prepared in local thermal states at different temperatures, employing a Nuclear Magnetic Resonance setup. We observe a spontaneous heat flow from the cold to the hot system. This process is enabled by a trade off between correlations and entropy that we quantify with information-theoretical quantities.
They linked the creation of the sun’s anti-entropic virucidal energy from the physiology of food energy-dependent pheromone-controlled reproduction to biophysically constrained viral latency in all living genera. Constrained viral latency exemplifies the constrained entropy that Schrodinger placed into the context of What is Life? (1944). The updated version of his work was reported as: Experiment shows that arrow of time is a relative concept, not an absolute one
The idea of entangled particles has been in the news a lot lately as researchers around the world attempt to use it for various purposes—but there is another lesser-known property of particles that is similar in nature, but slightly different. It is when particles become correlated, which means they become linked in ways that do not happen in the larger world. Like entanglement, correlated particles share information, though it is not as strong of a bond. In this new experiment, the researchers used this property to change the direction of the arrow of time.
Everything known to serious scientists about biophysically constrained energy-dependent RNA-mediated pheromone-controlled entropy (aka the “arrow of time”) is now referred to in the context of autophagy, which links the food energy-dependent fixation of amino acid substitutions to healthy longevity during species-specific developmental staging in species from microbes to humans.
See:Micro RNAs mir-184 and let-7 alter Drosophila metabolism and longevity
… adult-specific overexpression of let-7 in female nervous tissue increased median fly lifespan by ~22%. We provide evidence that this lifespan extension is not due to alterations in nutrient intake or to decreased insulin signaling.
That fact about biophysically constrained entropy (autophagy/the “arrow of time”) replaces all theories about the emergence of life and evolution of biodiversity. Ridiculous theories were based on the 2nd Law of Thermodynamics, which assumes there are no correlations between subatomic particles. Darwin’s “conditions of life” and “Kohl’s Laws of Biology” show that the correlations are manifested at every level of examination.
See: Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels
The feedback controls energy-dependent differences in H2, which consists of two different hydrogens. Control begins at the level of subatomic particles. The controlled differences link the speed of light on contact with water (H20) to all biodiversity via the physiology of pheromone-controlled reproduction. That fact is exemplified in Drosophila and in the Amish population of Berne, Indiana. That modern human population manifests a nutrient energy-dependent pheromone-controlled 10-year increase in their RNA-mediated lifespan.
The claim that “A null mutation in SERPINE1 protects against biological aging in humans ” can be viewed in the context of what Richard Feynman claimed about human idiocy. Mathematical models of energy-dependent biophysically constrained entropy link autophagy to healthy longevity. They link the virus-driven degradation of messenger RNA from mutations to all pathology. Only biologically uninformed science idiots publish research that supports ideas about mutation-driven evolution.
VIDEO
Few intelligent people would argue against the fact that life is food energy-dependent. But see:
7/25/13
Jay R. Feierman:
Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution.
My understanding is based on an understanding shared by many scientists and non-scientists, but no pseudoscientists.A third of Americans don’t believe in evolution
Ecological adaptation occurs via the epigenetic effects of nutrients on alternative splicings of pre-mRNA which result in amino acid substitutions that differentiate all cell types of all individuals of all species. The control of the differences in cell types occurs via the metabolism of the nutrients to chemical signals that control the physiology of reproduction.
These facts do not refute evolution; they simply refute the ridiculous theory of mutation-initiated natural selection that most people here were taught to believe is the theory of evolution.
That theory is far too ridiculous to be anything but a joke in the context of biological-based increasing organismal complexity. But here, we have lots of jokers, don’t we? The proof of ecological variation that appears to refute the theory of evolution, which actually refutes itself, is that ecological adaptations occur too fast for mutations to compete with them as a source of anything but diseases and disorders.
See also the attack on my scientific credibility by PZ Myers and his idiot minions: One crank dies, another rises to take his place (2014)
Is alternative splicing the only mechanism to create variants in cells? No, of course not. External signals cause changes in the phosphorylation state of proteins in the cytoplasm, for example, that can affect metabolic activity; no alternative splicing involved. Signals can also switch on and switch off specific genes, again, no alternative splicing needed.
Most of the serious scientists I know laugh at people like PZ Myers. Some of them use sarcasm to address the ignorance of pseudoscientists. For example, see: A not entirely serious future history of neuroscience (2017)Sarcasm alert. Thanks to Luca Turin for calling attention to this.
Author’s note: resting for a moment in a dark corner of the Society for Neuroscience conference’s poster hall, on the quiet solitude of the Wednesday afternoon in the History of Neuroscience aisle, a shambling figure, bent with age, appeared with a speed that belied his years. Suddenly lunging for me, he shoved a sheaf of papers into my hand, hissing in my ear “it gets worse — so much worse”. Startled, I glanced at the front page, and the date written at the top: 6th October 2106. “What is…” I began, but he’d already whirled away — “A warning!” he spat back over his shoulder. Then he stopped, growled “I hate this bit”, squeezed his conference badge — and vanished.
Excerpt 2)
2037: Janelia Farm announces its Drosophila model of schizophrenia. HHMI instructs it to diversify its range of species.
My addendum: Electron spin changes during general anesthesia in Drosophila (2014)
Back to the future: The insect-to-elephant model of pheromone-controlled biophysically constrained viral latency is abandoned, again. Insect pheromone in elephants
The insect-to-elephant model of the food energy-dependent pheromone-controlled physiology of reproduction links alternative splicing of pre-mRNA, which now are called microRNAs by all serious scientists, to survival of all individuals in all species. The virus-driven degradation of messenger RNA links mutations to all pathology.
When should you unfriend someone on Facebook?
What we need to remember is that the devil is in the details.
Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels (1990)An Evolving Approach: The Public Response to Darwinism at Abilene Christian University, 1935-1989 (Stone-Campbell Journal 20:2, 2017)
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Predicting naturally occurring viral latency
3
0
Quantum initiation of cold chemistry vs Hypeology (1)
4
0
Virus-driven genome engineering causes cancer?
2
0
The concept of a species (3)
4
0
The concept of a species (1)
2
0
The tipping point (revisited): 74,000 publications
4
0
MicroRNA-mediated alternative splicing (revisited)
4
0
Animal welfare vs human ethology
4
0
Biologically uninformed science idiot: Self-defense (3)
5
0
Biologically uninformed science idiot: Self-defense (1)
3
0
The eternal significance of microRNAs and the Vietnam Memorial (2)
4
0
The eternal significance of microRNAs and the Vietnam Memorial (1)
3
0
From quantum physics to quantum souls (5)
2
0
From quantum physics to quantum souls (2)
2
0
Epigenetic inheritance of spatiotemporal regulation (5)
8
0
Epigenetic inheritance of spatiotemporal regulation (3)
5
0
The Social Brain of Autism
3
0
Epigenetic inheritance of spatiotemporal regulation
4
0
Cracks in The Granite Wall (1)
4
0
The eternal significance of microRNAs (9)
2
0
The eternal significance of microRNAs (8)
2
0
The eternal significance of microRNAs (7)
3
0
The eternal significance of microRNAs (5)
2
0
A single base change refutes theistic evolution (2)
2
0
Ecological adaptations vs the randomness of evolution (3)
4
0
A single base change refutes theistic evolution
5
0
EDAR V370A and sympatric speciation
2
0
MicroRNA-mediated autophagy, denuclearization and eusociality
3
0
Virus-driven cystinosis
2
0
Environmental selection is natural selection (5)
5
0
Environmental selection is natural selection (4)
2
0
Environmental selection is natural selection (3)
3
0
Environmental selection is natural selection (2)
2
0
Environmental selection is natural selection
3
0
MicroRNA-mediated denuclearization (6)
2
0
MicroRNA-mediated denuclearization (2)
5
0
Abiogenesis vs microRNA biogenesis (3)
2
0
Abiogenesis vs microRNA biogenesis (2)
7
0
2018 March for Science vs microRNAs (2)
4
0
2018 March for Science vs microRNAs
7
0
The eternal significance of microRNAs (2)
3
0
The eternal significance of microRNAs (1)
< 1
0
Sympatric Speciation vs pseudosceintific nonsense (4)
2
0
Sympatric Speciation vs Pseudoscientific Nonsense (1)
4
0
Complexity: Routes and Patterns (4)
< 1
0
Is meat protein unhealthy? (2)
2
0
Is meat protein unhealthy? (1)
< 1
0
Laws of Biology / Rules of Life
3
0
Complexity: Routes and Patterns (2)
< 1
0
Less evolvable RNA-mediated ecological adaptations
3
0
RNA-mediated nutritional psychiatry (2)
2
0
RNA-mediated nutritional psychiatry
4
0
Odor activation of ATP (2)
2
0
Part 3: Light-controlled cell biology (revisited)
3
0
Part 2: Light-controlled cell biology (revisited)
2
0
Autophagy in health and disease (1)
3
0
Polymaths and paradigm shifts: From Asimov to Bear (5)
5
0
Polymaths and paradigm shifts: from Asimov to Bear (2)
4
0
Polymaths and paradigm shifts: from Asimov to Bear (1)
5
0
How to create biologically uninformed theorists
7
0
Carl Zimmer refutes theistic evolution (2)
2
0
Ecological adaptation: a new definition of heredity (4)
4
0
Ecological adaptation: A new definition of heredity (3)
4
0
Ecological adaptation: A new definition of heredity (1)
5
0
MicroRNAs biophysically constrain behavior
4
0
Creating biophysically constrained viral latency (2)
2
0
Light-activated carbon fixation did not evolve (4)
7
0
George Church refutes theistic evolution (4)
4
0
Conceptual critique: Innateness vs the death gene (1)
5
0
How to biophysically constrain the flu virus (1)
4
0
Cryo-EM: Linking spatial and conformational constraints
9
0
Subatomic: From thermophiles to humans (2)
6
0
A reversible TCA cycle in a thermophile (3)
4
0
A reversible TCA cycle in a thermophile (2)
3
0
A reversible TCA cycle in a thermophile
5
0
A mental health problem at the highest level (3)
7
0
Diet-driven RNA interference and mental health (3)
4
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (4)
8
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (3)
6
1
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (2)
4
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (1)
2
0
The MicroRNAome Strikes Back: A Sokalian hoax (10)
3
0
The MicroRNAome Strikes Back: A Sokalian hoax (9)
4
0
BiondVax Universal Flu Vaccine Patent
4
0
Diet-driven RNA interference and mental health (2)
3
0
The MicroRNAome Strikes Back: A Sokalian hoax (5)
6
0
The MicroRNAome Strikes Back: A Sokalian hoax (4)
5
0
The MicroRNAome Strikes Back: A Sokalian hoax (3)
4
0
The MicroRNAome Strikes Back: A Sokalian hoax (2)
6
0
The MicroRNAome Strikes Back: A Sokalian hoax (1)
4
0
The tipping point (revisted): 69,000 publications
4
0
A mental health problem at the highest level (2)
3
0
Diet-driven RNA interference and cancer prevention (3)
6
0
Enzyme-constrained interethnic diversity (8)
< 1
0
Enzyme-constrained interethnic diversity (7)
6
0
Diet-driven RNA interference and cancer prevention (2)
< 1
0
Diet-driven RNA interference and cancer prevention
5
0
Interethnic genetic similarities and differences (2)
4
0
Enzyme-constrained interethnic biodiversity (3)
3
0
Enzyme-constrained interethnic biodiversity (1)
5
0
Quantized energy-dependent viral trophism (2)
2
0
A Mathematical Model Links Quantum Physics to Quantum Souls (2)
4
0
The “walking fish” walks straight from quantum physics to quantum souls (5)
4
0
The “walking fish” walks straight from quantum physics to quantum souls (4)
11
0
The “walking fish” walks straight from quantum physics to quantum souls (3)
9
0
The “walking fish” walks straight from quantum physics to quantum souls (2)
3
0
The “walking fish” walks straight from quantum physics to quantum souls
6
0
A Mathematical Model Links Quantum Physics to Quantum Souls (1)
6
0
From base editing to RNA editing (7)
2
0
From base editing to RNA editing (6)
8
0
Who created your virus-driven death gene? (3)
3
0
From nitrogen atoms to ecosystems in all living genera
6
0
Energy-dependent base editing and correction of mutations (3)
3
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (5)
4
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (3)
3
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (2)
4
0
Darwinian adaptation: a clear evolutionary trail?
4
0
The tipping point (revisited): 68,000 publications
5
0
Agilent technology and energy-dependent autophagy
8
0
Tai Chi vs PTSD and cancer
< 1
0
Narcissistic egomaniacal and deadly denial of autophagy
6
0
Elsevier fails to support the concept of autophagy
4
0
From Autophagy.pro (transitions)
4
0
Nature vs Science and Autophagy.pro
7
0
Autophagy.pro vs Nature Publications Group
2
0
The overwhelming ignorance of sex researchers (2)
4
0
Who created your virus-driven death gene? (2)
10
0
Energy-dependent base editing and correction of mutations (2)
9
0
The overwhelming ignorance of sex researchers
5
0
Mouse morphs and primate diversity in 50 years
7
0
Two retractions of human idiocy
2
0
Exposing the 2nd Law to more ridicule (1)
6
0
Reporting new scientific truths is not allowed in the USA
3
0
Who created your virus-driven death gene? (1)
5
0
Denying Creation via RNA-directed DNA methylation
4
0
Light activated error-free DNA repair (3)
3
0
Light-activated error free DNA repair (2)
8
0
Schrodinger’s answer to Schrodinger’s question
3
0
MicroRNAs and the Cassandra syndrome (revisited)
4
0
Observing energy-dependent intelligence and human idiocy
4
0
A null mutation and healthy longevity?
4
0
Light-activated error free DNA repair
5
0
Achromobacter and killer theories
2
0
Eutrophication and phosphorylated biodiversity
6
0
Alternative splicing: a new therapy?
3
0
Epigenetic facts vs variable recombination theories
4
0
A mental health problem at the highest level
2
0
Selfish X-linked alleles and X chromosome inactivation
3
0
Natural selection for racism and all pathology
6
0
Pheromones biophysically constrain base editing and RNA editing
3
0
From base editing to RNA editing (5)
< 1
0
From base editing to RNA editing (4)
5
0
The next reformation: 500 years too late? (1)
< 1
0
The next reformation: 500 years too late? (2)
2
0
The next reformation: 500 years too late? (3)
5
0
Energy as information and Infowars
5
0
From base editing to RNA editing (2)
7
0
From base editing to RNA editing
2
0
Cryo-EM: More than a suggestion
< 1
0
Long-term adaptation replaces evolution (2)
2
0
Exome Sequencing Impact in Routine Care
4
0
Losers: rediscovering an epigenetic key
2
0
Virulence: Out of stock
2
0
Faith in evolution: Paleontology as a molecular science
5
0
Energy-dependent structure and function: Until death (5)
4
0
Energy-dependent structure and function: Until death (3)
3
0
Energy-dependent structure and function: Until death (2)
5
0
Energy-dependent structure and function: Until death (1)
4
0
Biophysically constrained intelligence vs human idiocy
4
0
Cryo-EM from atoms to ecosystems
6
0
Until death: Virus-driven failure of multisensory integration (1)
4
0
Entertaining yourself to death
6
0
Criticisms of a validated model
9
0
Predicting who wins the 2017 Nobel Prizes (5)
2
0
Predicting who wins the 2017 Nobel Prizes (3)
2
0
Predicting who wins the 2017 Nobel Prizes (2)
4
0
Predicting who wins the 2017 Nobel Prizes
4
0
1996-2016: Ignoring alternative splicings of pre-mRNA
7
0
Life and death via chemical effects on photosynthesis
8
0
Dispelling the ignorance of theorists
4
0
Sci-Hub vs limits on the dissemination of information
6
0
Evolutionary theories of epigenetic drift
2
0
Evolution outside the context of “the light of evolution”
6
0
Inventing “Transcriptome Trajectory Turning Points”
2
0
Optogenetics replaces fMRI but not pseudoscientific nonsense
2
0
Science vs Secularism: Molecular Mechanisms or Math?
6
0
MicroRNAs: Nature’s secret ingredient
2
0
A fear of pheromones (revisited)
6
0
Sexual communication signals: New Insights!
10
0
Quantum physics, Patrick Bateson, and neo-Darwinian nonsense
3
0
Host-derived creation of all pathology (2 of 2)
9
0
Host-derived creation of all pathology (1 of 2)
5
0
God vs host-derived creation of virus-driven pathology (2)
4
0
God vs host-derived creation of virus-driven pathology
6
0
Stem cells do not create themselves
3
0
Pseudoscientists hate what science explains! (3)
4
0
Your indifference is killing you and others
5
0
Your indifference is killing you and others (3)
4
0
Your indifference is killing you and others (4)
4
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4
0
Sunlight, phytochemicals, microRNAs and cancer
5
0
Solar analemma with a total solar eclipse
2
0
The Origin of Information (4)
4
0
Can protein folding chemistry be understood by theorists?
5
0
Evolutionary congruence (losers) vs ecological adaptation (winners)
3
0
Irreconcilable differences: food energy vs de novo assembly
2
0
Pattern recognition vs evolutionary processes (revisited)
7
0
New Testament Book Cover Refutes Theistic Evolution
7
0
Energy-dependent physical and biophysical constraints (10)
8
0
Energy-dependent physical and biophysical constraints (9)
3
0
Energy-dependent physical and biophysical constraints (8)
5
0
Energy-dependent physical and biophysical constraints (5)
7
0
Energy-dependent physical and biophysical constraints (4)
2
0
Energy-dependent physical and biophysical constraints (3)
2
0
Energy-dependent physical and biophysical constraints (2)
4
0
Cell type assembly and the space-time continuum
2
0
Epigenetic effects of stress by Bruce McEwen (2)
3
0
The emergence of light as energy from a life-giving star (2)
2
0
Milk-derived miRNAs, circulating microRNAs, DNA repair, and embryonic viability
2
0
The emergence of light as energy from a life-giving star
11
2
God’s shrinking role in salvation (3)
9
0
God's shrinking role in salvation (3)
9
0
MicroRNAs GnRH and the failure of sex research
7
0
God’s shrinking role in salvation (2)
5
0
God’s shrinking role in salvation
8
0
Food energy-dependent cell type differentiation (2)
10
0
Hard Science vs the neo-Darwinian “magic box”
9
0
MicroRNAs light up life
7
0
From E. coli to monkeys and mankind: Theories vs models (5)
5
0
From E. coli to monkeys and mankind: Theories vs models (4)
2
0
From E. coli to monkeys and mankind: Theories vs models
7
0
Food energy-dependent epigenetic adaptation (3)
3
0
Food energy-dependent epigenetic adaptation (2)
< 1
0
Food energy-dependent epigenetic adaptation
11
0
Energy-dependent epigenetic translation to mRNA stability (6)
8
0
Energy-dependent epigenetic translation to mRNA stability (5)
4
0
Energy-dependent epigenetic translation to mRNA stability (3)
5
0
Energy-dependent epigenetic translation to mRNA stability (2)
5
0
Energy-dependent microRNA biogenesis
4
0
Draining the academic swamp of parasites
3
0
The death of human ethology via ecology
7
0
The death of CRISPR; long live endogenous RNAi
5
0
Dispensing with all pseudoscientific nonsense about evolution (1)
5
0
The Virus-Driven Suicide March for Science
5
0
Virus-driven downsizing of the human brain (4)
2
0
Feng Zhang refutes theistic evolution
4
0
Open Science: Closed to facts about microRNAs
6
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3
0
Respiration-dependent endogenous RNA interference
4
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3
0
Cytosis: Biology content (2)
5
0
Sunlight bursts the social bubble of physics and math
3
0
Functionally interdependent editing and methylation
4
0
Cytosis: Biology Content
7
0
Light-activated feedback loops vs self-organization of ecosystems
7
0
Harvard researchers support young earth creationism
< 1
0
Cytosis: A Cell Biology Board Game
< 1
0
Food for thought: Penrose v Ellis (3)
4
0
Thinking about energy is not radical re-thinking
6
0
Food for thought: Penrose v Ellis (1)
5
0
Magnussen’s “Faith fools” keep the faith
3
0
Energy-dependent pheromone-controlled entropy (3)
2
0
Proof: Sunlight is energy as information
< 1
0
Sunlight: the essence of precision medicine and world peace
6
0
The essence of precision medicine: drug targets or healthy longevity?
4
0
The essence of precision medicine
4
0
Allen Institute confirms food energy is information
6
0
RNA-mediated adult learning, memory, and neurogenesis
3
0
Energy-dependent allelic imbalances, viruses, and pathology
3
0
Theistic evolutionists fight back and lose (3)
4
0
Theistic evolutionists fight back and lose (2)
4
0
Theistic evolutionists fight back and lose
4
0
Charles Darwin refutes theistic evolution
2
0
Bill Gates refutes theistic evolution (sequel)
8
0
Bill Gates refutes theistic evolution
4
0
Wikipedia refutes theistic evolution
4
0
Pseudoscientists fail to refute theistic evolution
4
0
Stuart Kauffman refutes theistic evolution
3
0
Francis S. Collins refutes theistic evolution
6
0
Happy Darwin Day (2017)
4
0
George Church refutes theistic evolution (2)
2
0
George Church refutes theistic evolution
5
0
Combating evolution: Battlefield medicine vs politicized science (2)
3
0
Natural selection for codon optimality and quantum viruses
5
0
Physicists: Desperate Acts (revisited)
6
0
Energy as information and constrained endogenous RNA interference (3)
4
0
Virus-driven energy theft and premature death
3
0
Dobzhansky 1973 and Precision Medicine (2)
5
0
Trump’s appeal to common sense (2)
3
0
Science journalists or paid propagandists? (4)
6
0
Dobzhansky 1973 and precision medicine
6
0
Twisted theories and weaponized facts
3
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6
0
Science journalists or paid propagandists? (3)
6
0
Critical values expose virus-driven energy theft (2)
4
0
Critical values expose virus-driven energy theft
6
0
Energy-dependent hydrogen bonds in supercoiled DNA
7
0
Energy-dependent chirality (2)
3
0
Energy-dependent chirality
6
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5
0
Vietnam Veterans and others with glioblastoma
3
0
Energy-dependent sensory maps (1996-2016)
5
0
Energy-dependent alternative splicings 1996 – 2016
12
0
Energy-dependent oscillating gene networks organize life
4
0
2016 obfuscated facts about energy as information
5
0
More refutations of neo-Darwinian nonsense
7
0
Re-inventing mutation-driven evolution (2)
4
0
Re-inventing mutation-driven evolution
3
0
Sudden death indel polymorphism
4
0
Bird-brained theorists
< 1
0
Explorers who do not know what is known
4
0
Autophagy is the antiphage defense strategy
3
0
Energy-dependent de novo creation and neurogenesis (2)
5
0
Energy-dependent de novo creation and neurogenesis
7
0
Theories vs facts about polycombic adaptation
3
0
Politicized science: The demise of RNA-mediated.com?
3
0
Combating evolution: Battlefield medicine vs politicized science
6
0
The futility of The Battlefield FB group
10
0
Happy biophysically constrained Thanksgiving (in the USA)
3
0
De novo gene creation: Ignoring the experimental evidence
7
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4
0
Light, behavior and autophagy, a gender-specific risk factor
4
0
Controlled amino acid treatment of all pathology
4
0
Energy-dependent purifying selection / autophagy (2)
2
0
Energy-dependent purifying selection / autophagy (3)
2
0
Energy-dependent purifying selection / autophagy (4)
2
0
Energy-dependent purifying selection / autophagy (6)
3
0
Energy-dependent purifying selection / autophagy
2
0
Optogenetics: Let there be virucidal light!
2
0
Base pairs, amino acids and phenotypes
10
0
Survivors of RNA-mediated terrorism
5
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3
0
Building delicious base pairs in class. It's elementary Watson and Crick
3
0
RNA-mediated “repurposing” is autophagy
2
0
RNA-mediated "repurposing" is autophagy
2
0
Epigenetics and autophagy vs mutations and evolution (8)
4
0
Energy-dependent maternal-to-zygotic transition
6
1
Virus-driven mutation or amino acid substitution
5
0
Epigenetically effected energy-dependent fluorescence
5
0
Epigenetics and autophagy vs mutations and evolution (7)
3
0
Epigenetics and autophagy vs mutations and evolution (5)
2
0
Epigenetics and autophagy vs mutations and evolution (4)
< 1
0
Epigenetics and autophagy vs mutations and evolution (2)
2
0
Epigenetics and autophagy vs mutations and evolution
< 1
0
From Precis to Proof in 6000 years (2)
5
0
From Precis to Proof in 6000 years
9
0
Coulombic interactions facilitate polycombic adaptation
5
0
Top-down adaptation vs bottom-up evolution
6
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
3
0
Polycombic ecological adaptation as a science, not a theory (2)
12
0
Attacking Young Earth Creationists
5
0
80 years of causal analysis (1936 – 2016)
11
0
The natural success of RNAi and failed treatment
7
0
Pheromone-controlled autophagy
4
0
Virus-mediated hecatombic evolution
2
0
Nutrient-dependent autophagy
3
0
Asking the right questions (1)
3
0
Life is energy-dependent task management
3
0
Hypothesis free pseudoscience vs facts (4)
5
0
Hypothesis free pseudoscience vs facts (1)
5
0
The last RNA-mediated theory killer
< 1
0
Base pairs, olfaction and RNA thermometers
4
0
Chromatin: The structure of DNA (2)
8
0
Chromatin: The structure of DNA (3)
4
0
Consciousness is simply food rearranged
2
0
Hydrogen-atom energy in DNA base pairs
6
0
A working model of “captured” genes
6
0
The Aquatic Ape / Waterside Ape divergence
6
0
Light energy-dependent active motifs
6
0
Light energy-induced base pair changes (2)
4
0
Light energy-induced base pair changes (1)
6
0
DNA repair via junk DNA (1)
5
0
Linking RNA structure to function
3
0
How did the innate immune system evolve?
4
0
The Aquatic Ape: New evidence?
4
0
Plant microRNAs slow virus-driven aging
3
0
Protecting 4 billion people from virus-driven entropy
< 1
0
Increased soil pH and nutrient availability
4
0
Energy-dependent cellular communication
3
0
Lawless evolution: No physics
4
0
Conserved biophotonic emissions
7
2
Antithetical conclusions (7)
3
0
Antithetical conclusions (4)
3
0
Anthetical conclusions (2)
5
0
Non-random pheromone-controlled cell type differentiation
3
0
RNAi: From magic bullet to billion dollar baby
4
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4
0
Energy-dependent natural fluorescence and bioluminescence
2
0
Pseudoscientists ignore what serious scientists prove
6
0
GC-rich neo-Darwinian train wreck
5
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1
0
Biophysically constrained cell type differentiation
3
0
From angstroms to ecosystems
7
0
Food supplement or licensed immunostimulant?
6
0
Q and A: Energy-dependent cell type differentiation
10
0
Biophotonics, glycobiology, quantized biodiversity (2)
19
0
The end of neo-Darwinism
5
0
Biophotonics, glycobiology, quantized biodiversity
4
0
The Origin of Information (2)
6
0
Did “Nature” kill Steve Jobs? (3)
10
0
Funding the Human Genome Project-Write
2
0
Did “Nature” kill Steve Jobs? (2)
6
0
Did “Nature” kill Steve Jobs?
3
0
Placing boundaries where none exist
< 1
0
Virus-driven downsizing of the human brain
2
0
MicroRNAs and sexual orientation
8
0
Innate immunity and multiplexing
7
0
RNA methylation (2)
7
0
Major transition ends use of silly theories
5
0
RNA methylation
2
0
Model vs theory: Progress report!
8
0
Masters of deception about nature (2)
7
0
Masters of deception about nature
8
0
The Mind’s Eyes (revisited)
10
0
Cracking the Olfactory Code?
5
0
Energy-dependent RNA methylation (9)
2
0
Energy-dependent RNA methylation (10)
4
0
Energy-dependent RNA methylation (7)
7
0
Energy-dependent RNA methylation (6)
9
0
Energy-dependent RNA methylation (5)
3
0
Energy-dependent RNA methylation (3)
10
0
Energy-dependent RNA methylation (2)
5
0
Energy-dependent RNA methylation (1)
6
0
Secular humanism and ecoterrorism
4
0
Thermotolerance and longevity (2)
3
0
War Games: False Flag Terrorism
5
0
Energy-dependent biodiversity (3)
7
0
RNA-mediated physics, chemistry, and molecular epigenetics (5)
6
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5
0
RNA-mediated physics, chemistry, and molecular epigenetics (2)
7
0
MicroRNAs and/or QTLs: Who buried what?
2
0
Wasted Templeton Funding (3)
2
0
Millions of water molecules vs years of evolution
2
0
A bumper crop of virus-infected weeds and people
2
0
Molecular Diagnostics: What is unprotected life?
2
0
Ricki Lewis’ Time Machine (4)
8
0
Half truths support theories without facts
4
0
Creating nutrient-dependent life with enough genes to survive
3
0
Confusing effects and affects of visual input
2
0
Nutrient-dependent life vs virus-driven pathology
4
0
Selective reporting of inferences: examples of pseudoscience
14
0
Ignore the evidence: Rachel Feltman
5
0
Virus-driven disorder prevention and health promotion
6
0
Jay R. Feierman: twenty years of antagonism
5
0
Energy dependent RNA-mediated immunity (5)
4
0
Energy dependent RNA-mediated immunity (3)
8
0
Energy-dependent RNA-mediated immunity (1)
10
0
RNA-mediated DNA modifications
5
0
Science vs semantics
4
0
From angstroms to ecosystems and entropy
2
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3
0
Effects on invertebrate GnRH and affects on primate behavior
6
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2
0
Will modern human populations adapt to the Zika virus?
5
0
Organic Compounds and the Miracle of Smell and Taste
7
0
Cancer: Evolution 2.0’s Blind Spot
13
0
Ricki Lewis’ Time Machine (2)
6
0
Ricki Lewis’ Time Machine
5
0
Virus-perturbed alternative splicings
3
0
Cytogenetic approaches link biosystems to ecosystems
3
0
The unoffically uninvited
3
0
Hydrogen-Atom Transfer in DNA Base Pairs (4)
4
0
Blood test links atoms to ecosystems
2
0
Stress-induced energy-dependent DNA repair
4
0
A failed theory of cancer: two more decades of pseudoscience
5
0
Ecological law, cooperation, and DNA repair
4
0
Amino acid substitutions, stress, and human behavior
3
0
RNA-mediated theory killers (11) (12) (13) (14) (15)
7
0
MicroRNA-mediated RNA epigenetics
2
0
Finding peace and π in the light of H bond energy
5
0
Epigenetic (re)programming of behavior (3)
5
0
Perry Marshall: too much information for atheist PZ Myers
3
0
Assumptions prove ignorance (2)
5
0
Epigenetic (re)programming of behavior
4
0
Assumptions prove ignorance
5
0
Did Dobzhansky see the UV light of creation?
10
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5
0
Does metabolism link beneficial mutations to cancer?
10
0
RNA-mediated theory killers (5)
2
0
Essential pseudoscientific concepts of atheism
3
0
RNA-mediated theory killers (2)
8
0
Natural cooperation and Evolution 2.0
6
0
A million dollar paradox?
2
0
A two-faced protein enables RNA-mediated DNA repair (3)
8
0
A two-faced protein enables RNA-mediated DNA repair (2)
4
0
Teaching the biologically uninformed
3
0
MicroRNAs vs Red Queen hypothesis
4
0
Hydrogen-Atom Transfer in DNA Base Pairs
9
0
Neo-Darwinism vs the neocortex
4
0
A two-faced protein enables RNA-mediated DNA repair
2
0
Phenols: Laws of physics meet biology
2
0
Stress-perturbed mitochondrial dysfunction (2)
5
0
Stress-perturbed mitochondrial dysfunction
4
0
Understanding cell type differentiation
3
0
Let there be anti-entropic light (3)
6
0
Theorists can’t understand biology
6
0
Models are not theories (3)
3
0
Too complex for the Complex Biological Systems Alliance
4
0
Receptor methylation controls behavior
2
0
Virus, transposon and plasmid evolution
< 1
0
MicroRNA-encoded behavior
7
0
Can veterans and other prisoners escape pseudoscience?
2
0
eQTLs and ecological adaptation
< 1
0
Ecological speciation. Get it, theorists?
< 1
0
The virome, microbiome, replisome and supercoiled DNA
2
0
Skip the politics; embrace the facts
5
0
Controled Stem Cell Expansion
3
0
Neo-Darwinian logic is nonsense
3
0
Biophysically constrained or unconstrained?
2
0
RNA-mediated retrotransposon-mediated biodiversity
3
0
Epigenetic inheritance of stress-perturbed protein folding
2
0
Energy and evolution: another opinion?
2
0
Let there be anti-entropic light (2)
4
0
Foundamentals of theory
4
0
Non-mainstream scientist shares Nobel prize in Medicine
3
0
Is mainstream science in “Science” pseudoscience?
5
0
Metaphysical science vs theory
4
0
Mechanisms of stress: from genes to cancer
9
0
Hijacked light energy and vertebrate pathology
4
0
Theorists have not seen the light
4
0
A 5-10K comparison of design principles to evolution
3
0
Alternative pre-mRNA splicing and ecological adaptation
7
0
Exosomes and the RNA-mediated future of medicine
5
0
Multi-omic analysis features (SNPs, miRNA)
3
0
Natural selection: an anti-entropic force?
2
0
Genome sequencing, cadherins, and quantum consciousness
6
0
“New” quantum biology. Pirating the old
3
0
Cell types, SNVs, CNVs, and chromosomes
3
0
Anti-entropic containment of energy: symbiosis 1.0
5
0
The “great filter” is an epigenetic trap
4
0
Information and communication
2
0
Rs3827760 is Val370Ala and EDARV370A
3
0
From “Blood Music” to Evolution 2.0
5
0
Thermodynamic constraints did not evolve
3
0
The stability of organized genomes (3)
3
0
Epimutation.com: a domain of confusion
8
0
Viruses, amino acids, and somatic cell types (3)
9
0
Viruses, amino acids, and somatic cell types (2)
5
0
RNA-mediated terms of virus-induced en-deer-ment
2
0
Hematopoiesis and practopoiesis
4
0
Becoming biologically informed (3)
3
0
Easy editing: Reinventing our RNA world
3
0
Riding the wrong direction
3
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6
0
MicroRNA controlled growth and brain development
7
0
MicroRNA – controlled ecological adaptations
5
0
“New” epigenetic mechanism for lifelong learning?
3
0
microRNAs and memory: Why trust a theory?
2
0
Protein folding and Google page rank
2
0
“Evolution” of sex differences?
2
0
RNA-mediated cell type differentiation: Honeybee
< 1
0
Creating and maintaining the human virome
2
0
Living the life that randomness created? (Sarcasm alert)
3
0
microRNAs, glycosylation, and genomes
4
0
Unknown mechanisms and conclusions
2
0
Alternative splicings: epigenetics meets pharmacogenomics
4
0
Epigenetic regulation of aging by glycine and GnRH
5
0
Pattern recognition: biogeochemical structure and function
5
0
Viruses and the human-like microbiome
3
0
Informing the biologically uninformed
< 1
0
Batch effect vs epigenetic effects
3
0
Missing a fact: microRNAs are genomic biomarkers
4
1
Bee-birthed epigenetics and primate cell types
5
0
Bees and primates automagically evolve
3
0
Targeting theories to fight disease
2
0
Ignoring systems complexity (it’s too complicated)
3
0
Five years of Ferguson
2
0
Virus-driven cancer treatment and prevention
2
0
A special issue on nutritional epigenetics
5
0
Retinoic acid + one receptor regulate the genome
3
0
Epigenetics: microRNAs effect an integrative pathway
4
0
Protein isoforms do not evolve
3
0
From gut bacteria to breast milk and back
5
0
Viruses in gut microbes
4
0
How to find a “holy grail” under your nose
3
0
MicroRNAs and the exposome (2)
< 1
0
MicroRNAs and the exposome
5
0
pH, water, amino acids and protein folding
4
0
Epigenetics vs the fossil record
4
0
RNA-mediated silencing of a chromosome
3
0
RNA-mediated cell types and precision medicine
5
0
Misunderstanding cancer
7
0
Amino acid-dependent cell type differentiation
8
0
A genetic variant refutes neo-Darwinism
6
0
Silencing genes and serious scientists
3
0
The miRNA/mRNA balance: a suboptimal strategy?
2
0
Nutrient-dependent microRNAs control cell types
6
0
MicroRNAs and memory
< 1
0
Graphic misrepresentations of ecological adaptation
2
0
Creating nothing but a theory (2)
4
0
Viruses and ecologically adapted animals
2
0
2 genes in 2 species (too expensive and too insignificant)
11
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4
0
Quantum correlations/pseudoscience
3
0
Anti-entropic solar energy
5
0
Correctly modeling biological energy
2
0
Questions about life’s diversity
21
0
UV-light mutations and gene loss (not gain)
5
0
Virus-driven origin of life
2
0
Luis P. Villarreal tells it like it is
3
0
RNA-directed gene choice
5
0
Walk towards the light
< 1
0
Two types of microRNA are not double agents
2
0
What about birds?
5
0
Implicating microRNAs in cancer
2
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2
0
Reverse phosphorylation
7
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3
0
Let there be anti-entropic light (1)
11
0
An epigenetic trap (the prequel)
5
0
Imagining that data historically supports evolutionary theory
7
0
Atheism: Arrogant, useless, and divisive ignorance
7
0
The anti-entropic force of "Nature"
2
0
Nutritional epigenetics, exercise, and immune system integrity
4
0
Military combat training to fight disease (2)
3
0
Theoretical physics and molecular biology
5
0
Atoms to ecosystems is not almost a molecular ecology
3
0
Epigenetic effects of viruses on cellular homeostasis (2)
2
0
RNA-mediated epigenetic modification via DNA-methylation
4
0
Quantum physics, quantum biology, and quantum consciousness
4
0
Biological energy and a microbiome model of a light-driven time machine
3
0
Quantum Superpositions: let there be light
4
0
Are viruses microRNAs? (2)
5
0
Are viruses microRNAs?
3
0
Sneaking up from behind
4
0
All of "like kind" in the (bigger) family
6
1
Environment epigenetically shapes the immune system
3
0
Beneficial microbes kill beneficial mutations
4
0
Constrained evolution is ecological adaptation
5
0
A single amino acid substitution differentiates cell types of E. coli
3
0
Unconstrained evolutionary innovability
4
0
Mutagenesis: Replacing facts with theories
5
0
ISHE's human ethology group
2
0
From Hydra to humans vs a Lakatosian research program
4
0
Unified nutritional and molecular mechanisms
9
0
Model organisms: the birds and the bees
3
0
Chemical ecology and RNA-mediated control of DNA loops
< 1
0
Jumping back: Science or Pseudoscience?
6
0
Single-cell level assay of protein biosynthesis and degradation
2
0
Dual genomes: exposing the evolution industry
5
0
Epigenetic pharmacology and RNA-mediated transciptional landscapes
3
0
RNA-mediated events and "The Theory of Everything"
4
0
Thermodynamic constraints and ecological adaptations sans evolution
6
0
Eliminating correlations from evolutionary ecology
6
0
RNA-mediated species specificity
2
0
Are mutations beneficial?
4
0
Ecological adaptations reported as evolution in insects and mammals
4
0
Biologists puzzled by evolved RNAs and decaying DNA
6
0
More than a bag of chemicals?
2
0
Nothing new under the sun, except pseudoscientific nonsense
6
0
Making sense of quotes scattered across disciplines
2
0
Intelligent viruses and cancers?
10
0
RNA eclipses the importance of DNA to cell type differentiation
4
0
Pharmacogenomics
3
0
Sexual differentiation of cell types in plants
2
0
A model of MHC 'evolution'
2
0
From deep time into real time: What evolutionary processes?
10
0
It’s cell type differention, not cell fate determination (2)
3
0
Are evolutionary theorists 'nob ends'?
5
2
ALPHA GENOMIX
7
2
No excuses: Creation and the meaning of organismal complexity
7
0
Nutrient-dependent gene duplication in plants (but not animals?)
4
0
No understanding of biodiversity
2
0
Behavioral ecology: please continue to believe in our fantasies
3
0
2014 and 2004 Nobel Prize in Medicine
3
0
RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2
2
RNA-mediated genetic engineering (Part 2)
3
0
RNA-mediated genetic engineering
2
0
Color vision refutes the evolutionary dogma of gene duplication
4
0
Forces of "Nature" limit dissemination of information
4
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2
0
RNA-mediated cell type differentiation and behavior
3
0
Different physical locations and different molecular mechanisms of health and disease
2
0
Metabolism, fixation, health or neurodegerative disorder
2
0
Physics, Chemistry, and Molecular biology (PCMb)
2
0
Physics denied; pseudoscientific nonsense accepted
2
0
Ecological variation and niche construction: 1, 2, 3
6
0
Epigenetically-effected metabolic shifts and ecological adaptations
3
0
Stop evolutionary theorists. Kill cancers
3
0
De novo gene Creation sans evolution of genes via mutations
4
0
RNA-directed DNA methylation and RNA-mediated events
5
1
Miracles are not miracles to evolutionary theorists
2
0
Seemingly futile cycles are not thermodynamically futile
3
0
“Kardashians” in science
< 1
0
Memory of repression and memory of behavior
2
0
Quantum physics meets Evolutionary Psychology News
2
0
Watching and waiting for more retractions
2
0
A molecular visualizer of worthwhile molecular biology
2
0
Some neuroscientists think a mutation led to human language development
< 1
0
Genotype, observed phenotype, and distinctly disordered behaviors
3
0
Is the problem an internet echo or Feierman's ethics?
2
0
Behavior (3): All responses are RNA-mediated in bees
3
0
RNA-mediated ecological adaptation is not evolution
2
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4
0
Behavior: The first response is RNA-mediated not genetically-determined
3
0
Pattern recognition and conserved receptors (TAARs)
5
0
Nutrient-dependent erythropoiesis and anemia
6
0
A relatively young branch of science called epigenetics
4
0
Biophysically constrained beginnings of RNA and DNA
4
0
Baby talk: More misrepresentations of ecological adaptations
2
0
Comparing divergent model organisms
2
1
Epimutations: Attacking pseudoscientific dogmas
4
0
Order and disorder: Ecological adaptations not mutations
6
0
microRNAs differentiate neuronal cell types
3
0
microRNAs and species relationships
3
0
The quantum biology of consciousness
3
0
Behavior is receptor-mediated
10
0
Cell-type differentiation
2
0
The wrong picture of our evolution
4
0
96 fixed amino acid substitutions, not 96 genes
6
0
Jay R. Feierman
3
0
Alternative splicings (very technical)
2
0
Social experiences epigenetically effect gene networks
2
0
Pheromone-controlled thermodynamics and cancer
2
0
Understanding the role of mutations and evolution
4
0
Pheromones and cancer
4
0
Epigenetics and metabolism converge with pheromone production
2
0
Never too young to learn WHAT?
< 1
0
Fatal attractions: a fear of pheromones
2
0
Eat like a monkey; act like a monkey
2
0
Insect to human cognition
2
0
Love is a receptor-mediated event: the pervasive influence of the late Robert L. Moss
3
0
Exercise Alters Epigenetics
2
0
Baiting the behaviorist(s)
3
0
The Sex Lives of Insects: Part III
3
0
The Sex Lives of Insects (Part II)
3
0
The Sex Lives of Insects
< 1
0
Honeybees, food odors, and perfume
< 1
0
(click to enlarge)