Virus-driven downsizing of the human brain (3) (8/9/16)

Virus-driven downsizing of the human brain (4) (4/23/17)

Who the heck is James V. Kohl?

Thanks for asking.

I’m in biochemistry/toxicology and was reading up on LUCA (aka Last Universal Common Ancestor). While Googling the work of Nick Lane, I stumbled upon the following page absolutely flaying Lane’s and others’ LUCA theories.

This guy, James V. Kohl, has many websites in which he writes about human pherormones and energy-dependent RNA-mediated cell type differentiation, among other things.

He seems both deranged and scientifically articulate. He remins me of how fundamental Christians get really into scientific terms and theories sometimes, but he doesn’t seem to be particularly religious.

It’s not just buzzwords, from what I can tell, but what’s his deal? Anyone heard of this guy before?

I am highly suspicious of this guy! I think he experiences some kind of anosognosia but I’m not sure who enables this or how it is perpetuated. He is very skillful and has the ability in his wording to even dupe other unsuspecting scientists. I’m sure he creates a lot of confusion if he somehow ends up presenting at meetings! very odd.

Do you know if he attends conferences to pick fights? He doesn’t seem to have published anything since 2013 when he worked in that lab. I get it, Kohl, peer review kind of sucks.

Hi, I came across this post because I had an interaction with this James V. Kohl while back on fb. To my worse juddgement, he kind of got me riled up and I said some rather stern words at him but otherwise innocuous things I called him out on. After searching myself on google, I see my name appears in his blog! He posted a couple things I allegedly said , claiming it is me along with my place of work from my fb profile so that they would come up together in a search. Also, he writes something about my comments towards him occuring on the day of the march for science which is neither here nor there. They don’t reveal anything to really worry about other than me accusing him of being a quack to make it look like I am trying to discredit him, a respectable scientist and that is not something someone at the Institute I work at would do to another scientist . He tries to play off everything with his seemingly impressive internet resume and has somehow, published his drivel somewhere, which appears on pubmed searches and uses that to legitimize himself. Go with your better judgment and do not engage with this individual. I am not surprised at all he has become a topic in reddit leading other burgeoning scientists towards confusion, but I see in all your comments your intincts on this guy are aligned, or the question of who he is would not have created this thread.

I removed the tags to the name of this antagonist and the name of his institution where he supposedly gets paid to do research on aging after he and his so-called lawyer threatened litigation, which would be a waste of my valuable time.

Clearly, there are people with academic credentials that make them appear to know more than I know about preventable and/or treatable pathology. But, to my knowledge, not many of them have linked the Virus-mediated archaeal hecatomb in the deep seafloor  from “…the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems…” to What’s in the Water at the Church Lab?

In the context of their failed pattern recognition, they are not likely to have linked the light-activated assembly of the microRNA-RNA-peptide nanocomplex and RNA interference to global biogeochemical cycles of protein biosynthesis and degradation, which protects all organized genomes in the context of the physiology of reproduction in all living genera via autophagy.

See: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems

See also:  Eukaryotic plankton diversity in the sunlit ocean It links the creation of the sun’s anti-entropic virucidal energy to the Virus-mediated archaeal hecatomb in the deep seafloor and all biodiversity on Earth via the light-activated assembly of the microRNA-RNA-peptide nanocomplex.

See for comparison: p62/SQSTM1 at the interface of aging, autophagy, and disease 2/21/14

…aging and age-related diseases can be delayed by modulating nutrient signaling pathways converging on the target of rapamycin (TOR) kinase, either by genetic or dietary intervention.

See for comparison: Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13

Adaptive evolution became ecological adaptions in:

Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems 4/11/14

Atoms to ecosystems became angstroms to ecosystems in Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18

People who have not learned what is known to serious scientists about the link from the virus-driven degradation of messenger RNA in marine bacteria to biophysically constrained viral latency in species from microbes to humans should not attack the credibility of serious scientists or threaten them with litigation.

See also the domains, and for comparison to published works or the ridiculous opinions of biologically uninformed theorists.

Simply put, all intelligent research on aging must begin from the assessment of facts that clearly show the mitochondrial redox system did not automagically create itself.

See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964)

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

See for comparison:  Mitochondrial Redox System, Dynamics, and Dysfunction in Lung Inflammaging and COPD 7/26/16

…we highlight the primary mitochondrial quality control mechanisms that are influenced by oxidative stress/redox system, including role of mitochondria during inflammation and cellular senescence, and how mitochondrial dysfunction contributes to the pathogenesis of COPD and its exacerbations via pathogenic stimuli.

Endogenous retroviruses are the pathogenic stimuli.  Others would have realized that many decades ago if they had linked the creation of the sun’s anti-entropic virucidal energy from the creation of ATP to the creation of  RNA and to naturally occurring RNA interference, which protects all organized genomes from the virus-driven degradation of messenger RNA.

For comparison, see what happens when researchers start with ridiculous theories about evolutionary divergence:

Development and initial characterization of xenomitochondrial mice (2004)

The selected donor backgrounds reflected increasing evolutionary divergence from MD [Mus musculus domesticus] mice and the resultant mitochondrial-nuclear mismatch targeted a graded respiratory chain defect.

Ku80 facilitates chromatin binding of the telomere binding protein, TRF2 9/15/10

The claims about “…non-homologous end joining repair of DNA double-strand breaks…” are still made despite the fact that pheromones biophysically constrain the hecatombic evolution of virus-driven pathology. That fact was first indicated in a review of research results published in1994. [Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)]

A study of the influence of pheromone stressor(s) on proliferating germ and somatic cells was performed on laboratory lines of house mouse in the context of the physiological hypothesis of mutation process, proposed by M.E. Lobashev in 1947. Data from experiments are presented, and results obtained during last 10-15 years are discussed. The adaptive role of cytogenetic and other observed pheromonal effects is considered. The possible existence of interorganism systems of genetic regulation is discussed, the search for and study of which may help in more complete understanding of the regularities of functioning of genetic material.

Only a biologically uninformed theorist could ignore what is known about energy-dependent cell type differentiation after games for ages 10+ became available for students to learn how the creation of subatomic particles must be linked from cytosis to autophagy and the innate protection from viral latency that supports claims about how sympatric speciation is linked to all biophysically constrained biodiversity on Earth.

Subatomic: An Atom-Building Board Game
Cytosis: A Cell Biology Board Game

A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!

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