Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells

Reported as:

Viral proteins may regulate human embryonic development

Excerpt: “…it’s not clear whether this sequence of events is the result of thousands of years of co-existence, a kind of evolutionary symbiosis, or if it represents an ongoing battle between humans and viruses.”

What is known to serious scientists about virus-driven entropic elasticity and the anti-entropic epigenetic effects of nutrients may never be known to theorists who think that species evolved over millions of years or hundreds of thousands of years.  Their ridiculous claims are based on de Vries definition of mutation and assumptions about how long it would take for accumulated mutations to link evolution to a new species.

They’ve ignored the facts about how ecological variation is linked to ecological adaptations and are continuing to do so because they can’t link the difference in viral microRNAs and nutrient-dependent microRNAs to RNA-mediated amino acid substitutions and cell type differentiation in all cells of all individuals of all genera.

See also: Epigenetics —an epic challenge to evolution This growing discipline challenges a number of ‘holy cows’ of neo-Darwinism

Excerpt: “…epigenetics suggests that latent genetic information of sorts is sitting in the DNA waiting for a particular environment in order to be switched on or off. It is like information in a book with certain pages stapled together, only to be opened and the information acted upon in certain environmental circumstances.”

Ask yourself why theorists don’t understand the biological basis of morphological and behavioral diversity when it arises via the conserved mechanisms of molecular epigenetics we detailed in our 1996 Hormones and Behavior review article: From Fertilization to Adult Sexual Behavior

See also: Breast milk may alter behaviour of babies

Excerpt: Breast milk contains a lot of sugars that infants can’t digest, but that feed bacteria that live in human intestines. Those bacteria don’t just help digest food, said Hinde.

“They can release chemical signals that travel to the infant’s brain and shape neurodevelopment.”

My comment: This happens in all vertebrates and invertebrates via the conserve molecular mechanisms of biophysically constrained nutrient-dependent RNA-mediated protein folding.

However, the bobtail squid has emerged as what may be the best example of how the epigenetic landscape is linked to the physical landscape of DNA by RNA-mediated events in all genera.

Addendum:

The Human Microbiome: Beyond the Gut

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“The human body hosts myriad distinct bacterial colonies that play important functions in both health and disease. These dynamic microbial colonies fluctuate over time and even form niche colonies in close proximity to one another. This webinar will highlight new research on the human microbiome and how this knowledge is being used to understand health and disease. The panelists will discuss advances in research on lung and skin microbiome. Attendees will have an opportunity to interact with the experts, ask questions, and seek advice on topics that are unique to their research.”

See also: Viral Protector

A retrovirus embedded in the human genome may help protect embryos from other viruses, and influence fetal development. by By Jef Akst | April 21, 2015

“[The work] shows that the protein products of a relatively ‘recent’ retrovirus integration”—HERVK took up residence in the human genome just 200,000 years ago—“are present very early on in the embryo, and could be involved in some critical developmental programs,” the Pasteur Institute’s Patrick Forterre, who was not involved in the research, told New Scientist.

To serious scientists the work links viral microRNAs and nutrient-dependent microRNAs from ecological variation to ecological adaptations, without speculation about how long it would take to link RNA-mediated amino acid substitutions to increasing organismal complexity of morphological and behavioral phenotypes.  For example, although the ecological adaptation that enables food finding behavior by a bacterium led to re-evolution of the flagellum “over-the-weekend” in this research report: Evolutionary Rewiring. If comparisons were made to the number of generations required for other organisms to adapt, the conserved molecular mechanisms that link ecological variation to ecological adaptations could be compared.

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