gene expression

Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)

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See also: Creating gravity, nucleic acids, receptors, and supercoiled DNA Scientists make first direct detection of gravitational waves Excerpt: Almost 100 years ago today, Albert Einstein predicted the existence of gravitational waves — ripples in the fabric of space-time that are set off by extremely violent, cosmic cataclysms in the early universe. With his knowledge … Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)

Neuroscience Virtual Event vs AAAS Symposium

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Neuroscience Virtual Event Abstract Submission Poster title: From hydrogen-atom transfer in DNA base pairs to ecosystems (March 16-17, 2016) Abstract: This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on DNA base pairs in solution and RNA-mediated amino acid substitutions to chromosomal rearrangements via pheromone-controlled changes in the microRNA / messenger RNA balance. … Neuroscience Virtual Event vs AAAS Symposium

Ecological genomics: teleophobes respond (too late)

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Forecasting Ecological Genomics: High-Tech Animal Instrumentation Meets High-Throughput Sequencing Conclusion: Twenty years ago, an essay about sequencing genomes and remotely tracking animals across the globe in real time would have been the subject of science fiction. In 2015, there are over 50,000 animals being tracked [12], and single research groups now sequence dozens, up to … Ecological genomics: teleophobes respond (too late)

RNA methylation, RNA-directed DNA methylation, learning and memory

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sink testing Lab medicine The illegal practice of providing false test results on clinical specimens–eg, vials of blood, urine specimens, that were deliberately discarded–ie, down the sink, without actually testing them Pylori Story #1: Acid Attack Pylori Story #2: Journey to the Center of the Stomach The “Modern Synthesis” is analogous to sink testing in … RNA methylation, RNA-directed DNA methylation, learning and memory

Epigenetic (re)programming of behavior (3)

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Bipolar drug turns foraging ants into scouts Excerpt: “DNA methylation has become nearly synonymous with epigenetics,” says Brendan Hunt, an insect geneticist at the University of Georgia in Griffin. “This research brings needed attention to the importance of other epigenetics marks, like histone modifications.” “We finally have a mechanism to understand ‘nurture’ in molecular terms,” … Epigenetic (re)programming of behavior (3)

Ecological adaptations you cannot live without

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Follow up to: Stress-perturbed mitochondrial dysfunction Summary: Bruce McEwen and others are taking the concept of RNA-mediated amino acid substitutions in cell type differentiation to a new level. They will force neo-Darwinian theorists to differentiate between mutations and amino acid substitutions. After February 14, 2016, if you still don’t know the difference, you may be … Ecological adaptations you cannot live without

RNA-mediated regulatory mechanisms link microbes to humans (3)

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See also: RNA-mediated regulatory mechanisms link microbes to humans and RNA-mediated regulatory mechanisms link microbes to humans (2) Regulation of gene expression The effects of miRNA dysregulation of gene expression seem to be important in cancer.[10] For instance, in gastrointestinal cancers, a 2015 paper identified nine miRNAs as epigenetically altered and effective in down-regulating DNA … RNA-mediated regulatory mechanisms link microbes to humans (3)

Natural cooperation and Evolution 2.0

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More than 45,000 published journal articles indexed on PubMed already contained the term microRNA before evolutionary theorists declared the microRNAs were linked from their emergence to all biodiversity via mutations and evolution in: MicroRNA mechanisms of action: what have we learned from mice? Conclusion:  We speculate that miRNAs emerged during evolution to increase the complexity … Natural cooperation and Evolution 2.0