Epigenome-wide Association Studies and the Interpretation of Disease -Omics Reported by Carl Zimmer in: Growing Pains for Field of Epigenetics as Some Call for Overhaul Excerpt: these experts “…argue that in some cases, changes to epigenetic marks don’t cause disease, but are merely consequences of disease. My comment: What kind of biologically uninformed expert or … Placing boundaries where none exist
Empty Seats as Zoologists Hog Royal Society Stage Excerpt: … they made sure to exclude, for instance, experts on viruses — the largest part of the biosphere — at a time when Zika continues to prove it can downsize the human brain in a flash and could have done the reverse at some point in … Virus-driven downsizing of the human brain
Mechanisms of Zika Virus Infection and Neuropathogenesis and Flavivirus infection requires specific host genes Excerpt: The researchers identified 9 genes that… are associated with the cell’s endoplasmic reticulum, where viral translation, replication, and assembly of viral particles takes place. Six of the genes also reduced infection of Zika, dengue, Japanese encephalitis, and yellow fever viruses … Virus altered thermodynamic stability
A neural circuit encoding sexual preference in humans Excerpt: We anticipate the identification of a core neural circuit for sexual preferences to be a starting point for further sophisticated investigations into the neural principles of sexual behavior and particularly of its aberrations. My comment: They link sexual orientation in yeasts to humans but fail to … MicroRNAs and sexual orientation
Experience-Dependent Accumulation of N6-Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in Mice Excerpt: Our findings suggest that m6A is regulated in an activity-dependent manner in the adult brain, and may function to fine-tune mRNA turnover during memory-related processes. My comment: They cite: Alarcón CR, Lee H, Goodarzi H, Halberg N, … RNA methylation, learning, memory and behavior,
Scientists Hope to Cultivate an Immune System for Crops by Carl Zimmer Excerpt: The complex microbial world in the soil may protect plants much like our immune system protects our bodies. My comment: The speed of light on contact with water links the sun’s quantized anti-antropic virucidal energy from the de novo creation of nucleic … Innate immunity and multiplexing
Conditioning as an adjunct in the pharmacotherapy of lupus erythematosus Several studies have provided evidence suggesting that “placebo effects” represent conditioning phenomena and that learning processes influence the response to placebo medication. This case report describes an adolescent with severe lupus erythematosus who received cyclophosphamide (CY) paired with taste (cod liver oil) and smell (rose … RNA methylation (2)
For an example of the ocean of information you must swim through to get to an important fact about virus-driven energy theft and all pathology, see: The bacteriophage ϕ29 tail possesses a pore-forming loop for cell membrane penetration (June 15, 2016) They cite “PrDOS: prediction of disordered protein regions from amino acid sequence” (2007). Excerpt: … Amino acids and virus penetration
Major transitions in human evolution This theme issue focuses on key evolutionary transitions to understand the interaction of biology, behaviour, culture and environment. This issue is dedicated to Richard Leakey, whose critical discoveries have provided evidence for many of the key phases, and who has inspired much of the work discussed here. This issue is … Major transition ends use of silly theories
This is a brief history of events that led me to found the domain RNA-mediated.com with some follow-up on the latest news about cell type differentiation In 2012, I attended this minisymposium 006.Transcribing Memories: New Mechanisms of Activity-Regulated Gene Expression and Their Roles in Experience-Dependent Plasticity. Description: Activity-regulated gene transcription is essential for orchestrating the … RNA methylation
