Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications ON 11/14/16 The co-author Mohamed Samir wrote: Because our article is among the top 25% most viewed and downloaded articles in the third quarter of 2016 in “Frontiers in Veterinary Science”, The editor of the journal has invited me to host … Energy-dependent maternal-to-zygotic transition
See also: Life is energy-dependent task management (2) Press Release: The Nobel Prize in Chemistry 2016 for the design and synthesis of molecular machines Excerpt: They have developed molecules with controllable movements, which can perform a task when energy is added. My comment: When energy is added is the key to understanding healthy longevity in … Life is energy-dependent task management
See also: Neuroplasticity Thanks to Teresa Binstock for calling my attention to this: Thanks to Anna Di Cosmo for calling the attention of others to this: My comment: Attempts to explain the “binding problem” of integration in the context of ecoimmunology and disease ecology compared to emergence and evolution are examples of how much … Theorists can’t understand biology
Relaxed genetic control of cortical organization in human brains compared with chimpanzees Abstract conclusion: A major result of increased plasticity is that the development of neural circuits that underlie behavior is shaped by the environmental, social, and cultural context more intensively in humans than in other primate species, thus providing an anatomical basis for behavioral … Cell type differentiation: atoms to ecosystems
Functional Conservation of the Glide/Gcm Regulatory Network Controlling Glia, Hemocyte and Tendon Cell Differentiation in Drosophila Abstract excerpt: High throughput screens allow us to understand how transcription factors trigger developmental processes including cell specification. A major challenge is the identification of their binding sites because feedback loops and homeostatic interactions may mask the direct impact … Conserved molecular mechanisms
Human Expression QTLs Are Enriched in Signals of Environmental Adaptation eQTLs is the term used to link base pair changes via proxies to single-nucleotide polymorphisms (SNPs) associated with complex traits and diseases. The direct link from the epigenetic landscape to the physical landscape of DNA via nutrient-dependent protein folding biochemistry and RNA-mediated gene duplication and … eQTLs and ecological adaptation
Predicted Inactivation of Viruses of Relevance to Biodefense by Solar Radiation (2005)Excerpt: Sunlight or, more specifically, solar UV radiation (UV) acts as the principal natural virucide in the environment. UV radiation kills viruses by chemically modifying their genetic material, DNA and RNA. See also: Let there be anti-entropic light (1) Excerpt: Nutrient-stress and social stress … Let there be anti-entropic light (2)
September 11, 2015 Case Western Reserve scientists discover long-sought genetic mechanism for cancer progression Excerpt: Action of a key lncRNA different in colon cancer versus normal colon tissue My comment: In yet another ridiculous misrepresentation of all that is currently known about how the epigenetic landscape is linked to the physical landscape of DNA in … Exosomes and the RNA-mediated future of medicine (3)
Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain Excerpt: The RNA-seq data enabled us to detect a positive correlation between developmental changes in the magnitude of parental biases and overall gene expression for most imprinted genes. Conclusion: At the level of the organism, our data uncover how paternal and maternal alleles … Viruses, amino acids, and somatic cell types (2)
Riding the Evolution Paradigm Shift With Eugene Koonin Excerpt: The entire evolution of the microbial world and the virus world, and the interaction between microbes and viruses and other life forms have been left out of the Modern Synthesis… Excerpt: [T]he entire ideology of personalized medicine should be taken with many grains of salt. My … Riding the wrong direction
