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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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Evolutionary theories of epigenetic drift (2)

Summary: For another refutation of neo-Darwinian pseudoscientific nonsense, see: Conformational landscape of isolated capped amino acids: on the nature of non-covalent interactions reported as:  Folding biomolecule model shows how form dictates function Mapping Human Genetic Ancestry (2007) …the sorting of such ancestral phenotypic polymorphisms in subsequent speciation events provides a parsimonious explanation why evolutionary derived characteristics are shared among species that are not each other’s closest relatives. The claims about evolutionary derived characteristics require acceptance of the belief that one…

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Evolutionary theories of epigenetic drift

Testing Two Evolutionary Theories of Human Aging with DNA Methylation Data My summary: Outside the context of food energy-dependent biophysically constrained pheromone-controlled viral latency, mutation accumulation (MA) and disposable soma (DS) provide possible explanations for the existence of human aging. For example, age-differentially-methylated sites across the genome showed significant MA-consistent increases in heritability with age or significant DS-consistent decreases in heritability. Their results supposedly show that both MA and DS play a role in explaining aging and aging-related changes but…

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Evolution outside the context of “the light of evolution” (2)

See first: Evolution outside the context of “the light of evolution” How many proponents of Intelligent Design never learned that Darwinian evolution was based on his “conditions of life?” ch 4 IV. Natural Selection; or the Survival of the Fittest  “IF under changing conditions of life…” ch 5 “…the greater variability of species having wider ranges than of those with restricted ranges, lead to the conclusion that variability is generally related to the conditions of life…” “…we cannot tell…

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Evolution outside the context of “the light of evolution”

Summary: The claim that two mutations led to the weekend resurrection of the bacterial flagellum cannot be supported with the claim that only one amino acid substitution differentiates the cell type of two different primate species (gorillas and humans) from two similar species (chimpanzees and humans). The fact that mutations are not amino acid substitutions can be supported in the context of food energy-dependent pheromone-controlled cell type differentiation in species from microbes to humans. Nothing in Biology Makes Any Sense…

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Inventing “Transcriptome Trajectory Turning Points”

Summary: They invented the term “Transcriptome Trajectory Turning Points” to prevent others from learning that virus-driven energy theft is the cause of all pathology. Scientists discover genetic timetable of brain’s aging process The biggest reorganisation of genes occurs during young adulthood, peaking around age 26, the team found. These changes affected the same genes that are associated with schizophrenia. The team says this could explain why people with schizophrenia do not show symptoms until young adulthood, even though the genetic…

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Optogenetics replaces fMRI but not pseudoscientific nonsense

Summary: The ability to evaluate spaciotemporal influences on health compared to virus-driven pathology must include a link from quantized energy to the creation of ATP and the creation of RNA. Hunting people down who are aware of that fact is difficult because most of them have ignored the facts from this 1964 publication. Ed Boyden and Optogenetics: The Future of Neuroscience (video) (transcript) What I’m trying to do now is see whether we can help people pilot crazy projects that…

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Methylation and the innate immune system (2)

Single methyl groups can act as toggle switches to specify transmembrane protein-protein interactions These results highlight the high intrinsic specificity of TMD interactions, demonstrate that a single methyl group can dictate specificity, and define the minimal chemical difference that can modulate the specificity of TMD interactions and the activity of transmembrane proteins. RNA-directed DNA methylation is energy-dependent. The “minimal chemical difference” is linked from the quantized energy of virucidal light to all biophysically constrained biodiversity via base pair changes, single…

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Science vs Secularism: Molecular Mechanisms or Math?

Summary: An example from ancient knowledge of trigonometry links pattern recognition as the basis for the science of creationism, and pattern recognition also is the basis for molecular biology. What form of virus-driven pathology would you most like to see eliminated from future consideration by serious scientists who know how energy-dependent RNA-mediated cell type differentiation occurs? In any case, a PubMed search for microRNA and your disease of choice will be enlightening. See for example: microRNA + Alzheimer’s or microRNA…

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Methylation and the Innate Immune System

Free Webinar Training: Methylation and the Innate Immune System Free Training: Methylation and the Innate Immune System Please send your questions, comments and feedback to: I sent these two questions in advance: 1) Does what organisms eat link food energy to RNA-directed DNA methylation and all healthy longevity via fixation of amino acid substitutions and transgenerational epigenetic inheritance in the context of the physiology of pheromone-controlled reproduction in species from microbes to humans? 2) Does the virus-driven theft of…

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MicroRNAs: Nature’s secret ingredient

The Secret Ingredient That Stops Honeybees From Becoming Queens Learning more about how these molecules can affect species in different kingdoms — like plants and insects or plants and humans — could help identify therapeutic applications for cancer treatments or to suppress allergic reactions, Dr. Askenase said. “Some important biological problems could now be addressed with this new knowledge of how nature works,” he said. Plant microRNAs in larval food regulate honeybee caste development Overall, our study uncovered a new…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Do not trust pseudoscientists
    Trust a Scientist: Sex Addiction Is a Myth A psychologist explains why sex addiction therapy is more about faith than facts, as told to Tierney Finster Excerpt 1)  During withdrawal, the brains of addicts create junctions between nerve cells containing...Read more