The tipping point (revisited): 87K (3)
(click to enlarge)
My NCBI » Saved Search Settings “What’s new for ‘microRNA’ in PubMed”(5/29/19)
170 new items were added to the indexed articles in one day for a total of 87,149 Co-circulation of genetically distinct highly pathogenic avian influenza A clade 2.3.4.4 (H5N6) viruses in wild waterfowl and poultry in Europe and East Asia, 2017–18 (4/22/19) can now be linked to A multicellular way of life for a multipartite virus (3/12/19).
It was reported as A New Discovery Upends What We Know About Viruses (3/14/19) and also as Viruses Can Scatter Their Genes Among Cells and Reassemble (5/21/19). Both articles link claims about how viruses adapt to cause pathology in hosts.
Those claims attest to the fact that the virus-driven degradation of messenger RNA has been linked from mutations to all pathology. Thank God, light-activated microRNA biogenesis has been linked from the physiology of food energy-dependent reproduction to biophysically constrained viral latency and healthy longevity via the fact that pheromones biophysically constrain viral latency and all pathology in species from nematodes to humans.
See: Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans (5/16/19)
“…pheromones correct heterochronic developmental cell lineage defects…”
That claim supports my refutation of neo-Darwinian pseudoscientific nonsense: Nutrient-dependent/pheromone-controlled adaptive evolution: a model (6/14/13). My refutation was cited in Role of olfaction in Octopus vulgaris reproduction (1/1/15) and Two fatty acyl reductases involved in moth pheromone biosynthesis (7/18/16), which linked Olfaction Warps Visual Time Perception (3/17/17) to Octopus vulgaris: An Alternative in Evolution (8/7/18)
…the occurrence of recently discovered adult neurogenesis and the high level of RNA editing give it a master key to face environmental challenges. Here we provide an overview of some of the winning evolutionary inventions that octopus puts in place such as the capacity to see color, smell by touch, edit own genes, and rejuvenate own brain.
Nobel Laureate, Ben Feringa indirectly linked claims about pheromone-induced thymus-linked rejuvenation of the brain to Biblical Prophesy in: The Future of Chemistry – Schrödinger at 75: The Future of Biology (11/20/18)VIDEO Transgenic Exosomes for Thymus Regeneration (4/24/19)
…our findings prove that exosomal Wnt4 and miR27b can efficiently prevent thymic adipose involution.
Reported as: Using Exosomes to Regenerate the Thymus (5/29/19)
..the exosomes from thymic epithelial cells had, until now, not been shown to be linked to thymus regeneration, and these results show that their contributions to the growth, maintenance and regeneration of the organ are significant. This opens the door to regrowing the thymus via the use of exosomes.
These initial results in mice are promising, and while we should be cautious about their translation to humans, there are grounds for some degree of optimism about the approach. This study’s in vitro and in vivo results suggest that exosomes offer an avenue for regenerating the mouse thymus and that they hold promise for translation to people in the future. There is, of course, more work to be done before we reach this point, but the march towards thymic regeneration continues apace.
See also: Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis (2011)Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
See also:MicroRNA-22 regulates thyroid cell growth and lipid accumulation via IL6R (6/1/19)Regulatory non-coding RNAs in nervous system development and disease (6/1/19)Potential miRNA-disease association prediction based on kernelized Bayesian matrix factorization (5/25/19)Carnosine induces intestinal cells to secrete exosomes that activate neuronal cells (5/28/19)Modeling and predicting developmental trajectories of neuropsychiatric dimensions associated with copy number variations (5/28/19)A 3D CdTe QDs-DNA Nano-Reticulation as Highly Efficient Electrochemiluminescent Emitter for ultrasensitive Detection of MicroRNA from Cancer Cells (5/28/19)
…this work could be readily extended for the detection of other biomolecules to provide a neoteric channel for disease diagnosis.
Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring (5/29/19)Breastfeeding Can Give Lifelong Immunity Against Infection, Say Scientists (5/29/19)
“We are particularly interested in how these findings may help to design maternal vaccine strategies that provide longer-term protection to children.”
Rather than link microRNAs in mammalian milk exosomes to biophysically constrained viral latency across species, they seize the opportunity to promote the development of vaccines.Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns (7/27/18)
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11
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The “walking fish” walks straight from quantum physics to quantum souls (2)
3
0
A Mathematical Model Links Quantum Physics to Quantum Souls (1)
6
0
From base editing to RNA editing (7)
2
0
From base editing to RNA editing (6)
8
0
Darwinian adaptation: a clear evolutionary trail?
4
0
Agilent technology and energy-dependent autophagy
8
0
Tai Chi vs PTSD and cancer
< 1
0
Narcissistic egomaniacal and deadly denial of autophagy
6
0
Elsevier fails to support the concept of autophagy
4
0
From Autophagy.pro (transitions)
4
0
Nature vs Science and Autophagy.pro
7
0
The overwhelming ignorance of sex researchers (2)
4
0
Energy-dependent base editing and correction of mutations (2)
9
0
Trashing the 2nd Law
7
0
The overwhelming ignorance of sex researchers
5
0
Two retractions of human idiocy
2
0
Exposing the 2nd Law to more ridicule (1)
6
0
Reporting new scientific truths is not allowed in the USA
3
0
Denying Creation via RNA-directed DNA methylation
4
0
MicroRNAs and the Cassandra syndrome (revisited)
4
0
A null mutation and healthy longevity?
4
0
Light-activated error free DNA repair
5
0
Achromobacter and killer theories
2
0
Eutrophication and phosphorylated biodiversity
6
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5
0
The next reformation: 500 years too late? (1)
< 1
0
The next reformation: 500 years too late? (2)
2
0
From base editing to RNA editing (2)
7
0
Cryo-EM: More than a suggestion
< 1
0
Exome Sequencing Impact in Routine Care
4
0
Virulence: Out of stock
2
0
Energy-dependent structure and function: Until death (5)
4
0
Energy-dependent structure and function: Until death (3)
3
0
Energy-dependent structure and function: Until death (2)
5
0
Energy-dependent structure and function: Until death (1)
4
0
Predicting who wins the 2017 Nobel Prizes (7)
4
0
Until death: Virus-driven failure of multisensory integration (1)
4
0
Entertaining yourself to death
6
0
Predicting who wins the 2017 Nobel Prizes (2)
4
0
Predicting who wins the 2017 Nobel Prizes
4
0
Sci-Hub vs limits on the dissemination of information
6
0
Evolutionary theories of epigenetic drift
2
0
Inventing “Transcriptome Trajectory Turning Points”
2
0
Methylation and the innate immune system (2)
4
0
Science vs Secularism: Molecular Mechanisms or Math?
6
0
Methylation and the Innate Immune System
< 1
0
Sexual communication signals: New Insights!
10
0
Host-derived creation of all pathology (2 of 2)
9
0
God vs host-derived creation of virus-driven pathology
6
0
Human Idiocy: The failure to link energy from electrons to ecosystems
19
0
Your indifference is killing you and others
5
0
Your indifference is killing you and others (4)
4
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4
0
The Origin of Information (4)
4
0
Energy-dependent physical and biophysical constraints (10)
8
0
Energy-dependent physical and biophysical constraints (8)
5
0
Energy-dependent physical and biophysical constraints (6)
8
0
Epigenetic effects of stress by Bruce McEwen (2)
3
0
God’s shrinking role in salvation (2)
5
0
MicroRNAs light up life
7
0
From E. coli to monkeys and mankind: Theories vs models (5)
5
0
Food energy-dependent epigenetic adaptation (2)
< 1
0
Energy-dependent epigenetic translation to mRNA stability (3)
5
0
Energy as information and constrained endogenous RNA interference (4)
7
0
What energy source do proteins prefer?
6
0
Draining the academic swamp of parasites
3
0
The Virus-Driven Suicide March for Science
5
0
Open Science: Closed to facts about microRNAs
6
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3
0
Respiration-dependent endogenous RNA interference
4
0
Cytosis: Gameplay Runthrough
3
0
Functionally interdependent editing and methylation
4
0
Cytosis: Biology Content
7
0
Harvard researchers support young earth creationism
< 1
0
Who will kill the billion dollar baby? Bill Gates or Donald Trump
3
0
Food for thought: Penrose v Ellis (3)
4
0
Magnussen’s “Faith fools” keep the faith
3
0
Proof: Sunlight is energy as information
< 1
0
Energy-dependent pheromone-controlled entropy (1)
4
0
The essence of precision medicine: drug targets or healthy longevity?
4
0
The essence of precision medicine
4
0
Allen Institute confirms food energy is information
6
0
RNA-mediated adult learning, memory, and neurogenesis
3
0
Energy-dependent allelic imbalances, viruses, and pathology
3
0
Theistic evolutionists fight back and lose
4
0
Bill Gates refutes theistic evolution (sequel)
8
0
Bill Gates refutes theistic evolution
4
0
Francis S. Collins refutes theistic evolution
6
0
Energy is information. Objections over ruled. You’re fired!
7
0
Happy Darwin Day (2017)
4
0
George Church refutes theistic evolution (3)
5
0
George Church refutes theistic evolution
5
0
Mitochondria do not adapt
2
0
Energy as information and constrained endogenous RNA interference (2)
2
0
Dobzhansky 1973 and precision medicine (5)
3
0
Dobzhansky 1973 and precision medicine (4)
5
0
Science journalists or paid propagandists? (4)
6
0
Science journalists or paid propagandists? (2)
3
0
Critical values expose virus-driven energy theft (2)
4
0
Critical values expose virus-driven energy theft
6
0
Energy-dependent hydrogen bonds in supercoiled DNA
7
0
Energy-dependent chirality (2)
3
0
Energy-dependent chirality
6
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5
0
Vietnam Veterans and others with glioblastoma
3
0
Energy-dependent sensory maps (1996-2016)
5
0
Re-inventing mutation-driven evolution (2)
4
0
Explorers who do not know what is known (2)
6
0
Autophagy is the antiphage defense strategy
3
0
Combating evolution: Battlefield medicine vs politicized science
6
0
The futility of The Battlefield FB group
10
0
Metabolic Phenotyping Research
2
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4
0
Energy-dependent purifying selection / autophagy (3)
2
0
Energy-dependent purifying selection / autophagy (6)
3
0
Energy-dependent purifying selection / autophagy
2
0
Optogenetics: Let there be virucidal light!
2
0
Epigenetics and autophagy vs mutations and evolution (8)
4
0
Virus-driven mutation or amino acid substitution
5
0
Epigenetically effected energy-dependent fluorescence (2)
6
0
Epigenetically effected energy-dependent fluorescence
5
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6
0
From Precis to Proof in 6000 years (2)
5
0
From Precis to Proof in 6000 years
9
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1
0
Polycombic ecological adaptation as a science, not a theory (2)
12
0
Biological evolution as a philosophy, not a science
6
0
80 years of causal analysis (1936 – 2016)
11
0
The natural success of RNAi and failed treatment
7
0
Life is energy-dependent task management (2)
3
0
Life is energy-dependent task management
3
0
Hypothesis free pseudoscience vs facts (1)
5
0
Chromatin: The structure of DNA
6
0
Hydrogen-atom energy in DNA base pairs
6
0
DNA repair via junk DNA (2)
5
0
The Aquatic Ape / Waterside Ape divergence
6
0
Light energy-induced base pair changes (2)
4
0
Light energy-induced base pair changes (1)
6
0
How did the innate immune system evolve?
4
0
The Aquatic Ape: New evidence?
4
0
Protecting 4 billion people from virus-driven entropy
< 1
0
Lawless evolution: No physics
4
0
Conserved biophotonic emissions
7
2
Antithetical conclusions (7)
3
0
Non-random pheromone-controlled cell type differentiation
3
0
RNAi: From magic bullet to billion dollar baby
4
0
GC-rich neo-Darwinian train wreck
5
0
From angstroms to ecosystems
7
0
Food supplement or licensed immunostimulant?
6
0
Virus-driven downsizing of the human brain (3)
4
0
The end of neo-Darwinism
5
0
Biophotonics, glycobiology, quantized biodiversity
4
0
The Origin of Information (2)
6
0
Did “Nature” kill Steve Jobs? (3)
10
0
Did “Nature” kill Steve Jobs? (2)
6
0
Did “Nature” kill Steve Jobs?
3
0
Virus-driven downsizing of the human brain (2)
< 1
0
Placing boundaries where none exist
< 1
0
Innate immunity and multiplexing
7
0
RNA methylation (2)
7
0
Major transition ends use of silly theories
5
0
Masters of deception about nature (2)
7
0
Cracking the Olfactory Code?
5
0
Energy-dependent RNA methylation (9)
2
0
Energy-dependent RNA methylation (7)
7
0
Energy-dependent RNA methylation (6)
9
0
Energy-dependent RNA methylation (5)
3
0
Energy-dependent biodiversity
5
0
Countdown to Genetics and Genomics
< 1
0
Energy-dependent creation and entropy
4
0
RNA splicing, genetic variation, and disease
2
0
Half truths support theories without facts
4
0
Ignore the evidence: Rachel Feltman
5
0
RNA-mediated DNA modifications
5
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3
0
The Light and Darkness of “Evolution 2.0”
11
0
Ricki Lewis’ Time Machine
5
0
Hydrogen-atom transfer in DNA base pairs (5)
10
0
Blood test links atoms to ecosystems
2
0
Finding peace and π in the light of H bond energy (2)
8
0
Assumptions prove ignorance
5
0
RNA-mediated theory killers (4)
9
0
RNA-mediated theory killers (2)
8
0
Sulfated steroids and RNA-mediated identity codes
< 1
0
Sensationalizing no new mechanism
2
0
Controled Stem Cell Expansion
3
0
Mystery machine vs model (3)
2
0
Thermotolerance and Longevity
57
0
Ecology replaces the extended evolutionary synthesis
4
0
MicroRNA controlled growth and brain development
7
0
“New” epigenetic mechanism for lifelong learning?
3
0
Unconscious affect (revisited)
2
0
Olfactory perception of genetic information
2
2
Epigenetic regulation of aging by glycine and GnRH
5
0
A lighting requirement for life
11
3
Retinoic acid + one receptor regulate the genome
3
0
Epigenetics: microRNAs effect an integrative pathway
4
0
How to find a “holy grail” under your nose
3
0
Re-inventing a completely new thing
4
0
Viruses and ecologically adapted animals
2
0
RNA-directed gene choice
5
0
Walk towards the light
< 1
0
Two types of microRNA are not double agents
2
0
Imagining that data historically supports evolutionary theory
7
0
All of "like kind" in the (bigger) family
6
1
Environment epigenetically shapes the immune system
3
0
From Hydra to humans vs a Lakatosian research program
4
0
Unified nutritional and molecular mechanisms
9
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6
0
Dual genomes: exposing the evolution industry
5
0
Thermodynamic constraints and ecological adaptations sans evolution
6
0
Eliminating correlations from evolutionary ecology
6
0
The key to science: experimental evidence
5
0
Ecological adaptations reported as evolution in insects and mammals
4
0
More than a bag of chemicals?
2
0
Nothing new under the sun, except pseudoscientific nonsense
6
0
We need pattern recognition, not a prologue
6
0
Sexual differentiation of cell types in plants
2
0
No understanding of biodiversity
2
0
Understanding physical forces of ecological variation and adaptation
< 1
0
Eliminating evolutionary theory
3
0
Unassailable evidence vs assumptions
4
0
Forces of "Nature" limit dissemination of information
4
0
Systems biology and memory disorders
3
0
Physics, Chemistry, and Molecular biology (PCMb)
2
0
Physics denied; pseudoscientific nonsense accepted
2
0
Ecological variation and niche construction: 1, 2, 3
6
0
Epigenetically-effected metabolic shifts and ecological adaptations
3
0
RNA-directed DNA methylation and RNA-mediated events
5
1
Quantum physics meets Evolutionary Psychology News
2
0
Insect homology and diversity attributed to mutations
2
0
Comparing divergent model organisms
2
1
Order and disorder: Ecological adaptations not mutations
6
0
Drunks and Monkeys: Pseudoscientific nonsense
2
0
The quantum biology of consciousness
3
0
Nutrition, pheromones and cancer (2)
2
0
Chromosomal rearrangements and ecological adaptations
4
0
Don't tell the Creationists
2
0
Understanding the role of mutations and evolution
4
0
Music to our ears and song in birds: a common sense approach
2
0
Fatal attractions: a fear of pheromones
2
0
The Knowing Nose: Chemical Signals Communicate Human Emotions
< 1
0
Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
2
0
Pheromonemotionally speaking
2
0
Playing with breasts (e.g, with a new THEORY of why only heterosexual men love them)
3
0
Pheromones and multicellularity
< 1
0
Human pheromones are like sugar (and spice)
< 1
0
A thought experiment
3
0
More than speculation: adaptive evolution in species from microbes to man
2
0
Human pheromones and your immune system
< 1
0
Human Pheromones in Socioaffective Neuroscience & Psychology
2
0
Pheromones and the “Bruce effect” in wild or domesticated horses and primates
2
0
They are what they eat, and so are we
2
0
How memory works
2
0
A Preoccupation With Modesty…
2
0
Pheromones: from microbes to man
< 1
0
The biology of behavior: Seeing more clearly
< 1
0
Effects of pheromones on menstrual synchrony and a gay man
2
0
Did viruses make mammals communicate with pheromones?
2
0
Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1
0
Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
2
0
Epigentics and the baby connectome
2
0
Cookbook chemistry: food odors and hormones
< 1
0
Epigenetics and the connectome
2
0
Human pheromones and food odors
< 1
0
Pheromones and the Evolution of Drug Resistance
< 1
0
Human pheromones provide clues to personality
< 1
0
How pheromones work (in 57 words or more)
< 1
0
Pheromone-enhanced behavior in sexually inexperienced females
2
0
Avian ‘Axe effect’ attracts attention of females and males
2
0
Human pheromones: social odors and food odors
< 1
0
Avian recognition of human faces
< 1
0
Human Pheromones Affect Women's Behavior
2
0
A lesser role for olfaction and pheromones in humans?
1
0
Creating a Myth
< 1
0
Pheromones in birds, other mammals, and us
< 1
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4
0
Social selection: genetic contribution of viruses to life on earth
< 1
0
Wikipedia comments by James V. Kohl
5
0
Excellent new book about pheromones
< 1
0
Study design| Psychophysics experiment | Perspective on conditioning
< 1
0
Adrenarche and odor preferences
2
0
For ethologists: Observation does not trump molecular biology
2
0
Human Pheromones and The Philosophy of Science
2
0
Genes, Hormones, and Behavior (for other scientists)
4
0
Love at first sight: Selective breeding, pheromones, and Divine intervention
3
0
A fundamental attribution error: Love at first sight
3
0
Human Pheromones
< 1
0
Pheromones and olfaction in the birds and the bees: from yeasts to you
2
0
Debunking the myth of pheromones
< 1
0
Tears and fears of pheromones
2
0
Exotic Pheromones and Concentrates
2
0
Marketing vs. the truth about human pheromones
2
0
Epigenetics, science fiction, and scientific fact
2
0
Results: increased flirtatious behavior and self-reported attraction
2
0
Is it what he or she sees in you, or is it your pheromones?
2
0
Product comparisons and human pheromone sciences
3
0
Conditioning of the human pair bond by human pheromones
< 1
0
Conditioned sexual arousal to odor
2
0
Scent signals
< 1
0
Pheromones and signature mixtures
2
0
Comparative biology of pheromonal communication
< 1
1
Food preferences and mate preferences
< 1
0
Presentation on Human Pheromones delivered on August 3, 2010
2
0
Sold on the human VNO?
< 1
0
Effects of pheromones attributed to touch (in mice)
< 1
0
How pheromones work by James V. Kohl
2
0
Pheromones of pregnant women effect prolactin in men
< 1
0
Another book author's comment on "The Great Pheromone Myth"
< 1
0
An attempt to change the concept
< 1
0
Luteinizing hormone, sex, and smell (18 years later)
2
0
(click to enlarge)