Codon optimality vs systemic fraud (1)

By: James V. Kohl | Published on: June 5, 2022
Codon optimality vs systemic fraud (1)(click to enlarge)

Two summaries of neo-Darwinian evolutionary theory:

Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.

…yeast receptors trigger activation of heterotrimeric G proteins just as mammalian receptors do, this conserved signaling pathway must have been present in the common ancestor of yeast and humans.

Unless you are a biologically uninformed theorist, see first Epistemic corruption (10)

Watch for my next 10-part series on Codon optimality vs systemic fraud. I will link it to the fraudulent representations in the special issue of Science Magazine published on 5/27/22 as “The Systemic Microbiome” and the molecular epigenetics section of our 1996 Hormones and Behavior review of energy-dependent microRNA-mediated stem cell creation and differentiation: From Fertilization to Adult Sexual Behavior

Neo-Darwinian theorists have since bastardized everything known to serious scientists about biophysically constrained viral endemicity across kingdoms.

See: Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system” 2/27/15 was reported as

and linked from
3) the end of the 1918 Spanish influenza via A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission 2/3/07 to former President Trump’s 4/23/20 claim that
The fact that sunlight and humidity protect all organized genomes from the virus-driven degradation of messenger RNA and all virus-driven pathology has been placed into the context of this historical perspective from 5/31/22.
Molecular phylogenies map to biogeography better than morphological ones

…molecular trees provide a better fit to biogeographic data than their morphological counterparts and that biogeographic congruence increases over research time. We find no significant differences in stratigraphic congruence between morphological and molecular trees.

The congruence of morphological and molecular trees has consistently been placed by intelligent serious scientists into the context of sympatric speciation.
A Google search for sympatric speciation suggests that it occurs when there are no physical barriers preventing any members of a species from mating with another, and all members are in close proximity to one another. A new species, perhaps based on a different food source or characteristic, seems to develop spontaneously.

If a different food source is required, there is no support for the claim that new species develop spontaneously. For comparison to the magic of spontaneous sympatric speciation, Thomas Hunt Morgan (1910) presciently linked nutrient-dependent pheromone-regulated genetic processes of reproduction from chromosomal rearrangements in flies to sympatric speciation across kingdoms via natural selection for energy-dependent codon optimality and fixation of amino acid substitutions in organized genomes.

The facts were subsequently placed into the context of prevention of all mental and physical pathology in “Puberty: ontogeny, neuroendocrinology, physiology, and disorders.” (1992) Williams Textbook of Endocrinology.

“noradrenergic, dopaminergic, serotoninergic, and opiotergic pathways; inhibitory neurotransmitters (e.g., gamma aminobutyric acid) and excitatory amino acids (e.g., glutamic and aspartic acids); and other brain peptides including pineal secretions (melatonin) and corticotrophin releasing hormone, and the complex interactions among them are subtle but functional species-specific influences on the electrochemical transmission of neuronal signals that the hypothalamus translates to the chemical signal GnRH. (p. 1164).

The claim about the chemical signalling pathways was cited in: Molecular Mechanisms of Hormone Actions on Behavior Anne M. Etgen, ‎Donald W. Pfaff – 2010 Neuroendocrine Regulation of Puberty
See also: Williams Textbook of Endocrinology, 12th Edition, which bastardized the claims of all intelligent serious who understand the molecular mechanisms of behavior by placing them into the context of: THE EVOLUTIONARY PERSPECTIVE

Hormones can be defined as chemical signals secreted into the bloodstream that act on distant tissues, usually in a regulatory fashion. Hormonal signaling represents a special case of the more general process of signaling between cells. Even unicellular organisms, such as baker’s yeast, Saccharomyces cerevisiae, secrete short peptide mating factors that act on receptors of other yeast cells to trigger mating between the two cells. These receptors resemble the ubiquitous family of mammalian seven-transmembrane spanning receptors that respond to ligands as diverse as photons and glycoprotein hormones. Because these yeast receptors trigger activation of heterotrimeric G proteins just as mammalian receptors do, this conserved signaling pathway must have been present in the common ancestor of yeast and humans. Signals from one cell to adjacent cells—so-called paracrine signals—often trigger cellular responses that use the same molecular pathways used by hormonal signals.

No experimental evidence of biologically based cause and effect is linked to a common ancestor of yeast and humans. Thank God, my mentor, Bruce S. McEwen, told me I needed to link the claims of Robert L. Moss about c-fos activation in GnRH neurons to biophysically constrained ATP-dependent RNA-mediated protein folding chemistry via God’s Creation of RNA.
See for comparison: The extent of codon usage bias in human RNA viruses and its evolutionary origin (2003)

…the strong correlation between base and dinucleotide composition and codon usage bias suggested that mutation pressure rather than natural (translational) selection is the most important determinant of the codon bias observed.

The truth about natural selection for energy-dependent codon optimality can be linked to every indexed publication that mentions microRNAs and allostery. For instance, Domino effect in allosteric signaling of peptide binding 5/28/22 links Peptide synthesis at the origin of life 11/13/20 from Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 to more than 200 patents for therapeutic solutions that link stem cells to prevention of virus-driven pathology. Please revisit any model that links the energy-dependent architecture of RNA-peptide interactions at the origin of life to viral endemicity and healthy longevity across kingdomss.
For instance, light-activated microRNA biogenesis has been linked from quantum coherence to coherently organized biology via Translation affects mRNA stability in a codon-dependent manner in human cells (2019) and what is known about the chemistry-to-biology (CTB) transition.
The transition links light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry via the pH-dependent physiology of pheromone-regulated genetic processes of reproduction and the patented cure for all virus-driven pathology held by George M. Church et al.
RNA-Guided Human Genome Engineering  7/2/15
Details of these all encompassing works on natural selection for codon optimality and protection from viruses were included in the STEM toy “Genotype” for ages 14+ Note, however, it is not legal to patent a naturally occurring process that links God’s Creation of sunlight and humidity from photosynthesis to protection from viruses across kingdoms.
See also: Distinct responses to rare codons in select Drosophila tissues 5/6/22. Reported as: Fly researchers find another layer hiding in the code of life 5/19/22

A decade after solving the structure of DNA as a double helix of the bases A,C, T and G, Francis Crick went on to decode the intermediate step by which three of these letters are translated into a “codon,” the recipe for a single amino acid, the building block of protein.

That fact casts doubt on this claim from A universal trend of amino acid gain and loss in protein evolution 1/19/05

Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.

See for comparison:  How life could have arisen on an ‘RNA world’ 5/11/22

At the moment, the ribosome simply falls from the heavens,” says Thomas Carell, a chemist at Ludwig Maximilian University of Munich.

See for comparison: MicroRNAs affect GPCR and Ion channel genes needed for influenza replication 11/17/21
There is no mention of amino acids in the context of viral replication. But wait!
Codon-specific Ramachandran plots show amino acid backbone conformation depends on identity of the translated codon 5/20/22

This shows that there exists a dependence between codon identity and backbone torsion of the translated amino acid.

See for comparison: A microRNA or messenger RNA point of departure estimates an apical endpoint point of departure in a rat developmental toxicity model 5/21/22
With no mention of the fact that amino acid substitutions determine the energy-dependent endpoint compared to the virus-driven degradation of mRNA, which links mutations to all diseases, the context of the microRNA/messenger RNA (mRNA) balance goes missing, and facts become theories.
On 6/26/19, a friend and I stopped at the Scopes Museum in Dayton, Tennessee to make sure I could view this presentation of facts on my laptop computer via a hotspot wi-fi connection.
See: Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner 6/26/19 (available for free on demand with registration).
I may try to find my on-location video to show that, as predicted, the presentation put an end to all the nonsense about natural selection for beneficial mutations and evolved biodiversity during billions to millions of years. That pseudoscientific nonsense has been touted since it began, a few decades after the time of the Scopes Trial in 1925.
On 6/26/19, Ariel Bazzini presciently established that God’s ATP-dependent Creation of RNA links microRNA-mediated pH-dependent fixation of amino acid substitutions from quantum coherence to coherently organized biology via microRNA-mediated stem cell creation.
See: MicroRNAs organize intrinsic variation into stem cell states 3/5/20

…naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology.

See also: Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition 7/9/16

The amino acid optimality code (Fig 6) provides an alternative perspective on sequence changes between paralogs in evolution and human disease.

See for comparison to Bazzini’s works: Exploring evolutionary immunogenomics: Lessons from our ancestors and past pandemics 4/20/22
It’s a theory-based killer of men, women, and children.

During this webinar, viewers will:

Gain insight into how past pandemics, such as Yersinia pestis, the agent of the Black Death, led to the evolution of the human immune system

Discover how the unique immunogenetic variation in present-day populations has impacted population differences in immune response to pathogens and susceptibility to immune-related disorders

Learn how cutting-edge techniques, such as RNA sequencing (RNA-seq), are used in evolutionary immunogenomics

SARCASM ALERT:  Someone else may want to link the pseudoscientific nonsense about mutations and evolutionary immunogenomics to unnecessary suffering and premature death. No wait! They already have. It seems like only yesterday. This is when it happened.
See: Codon optimality-mediated mRNA degradation: Linking translational elongation to mRNA stability 4/21/22

…transient pauses induce a unique ribosome conformational state that is probed by the deadenylase complex, thereby inducing an orchestrated set of events that enhance both poly(A) shortening and cap removal. Together, these data imply that the coding region of an mRNA not only encodes for protein content but also impacts protein levels through determining the transcript’s fate.

See also: autophagy.pro microRNA.pro and learn more about how to prevent virus-driven existential threats at RNA-mediated.com as this 10-part series continues.

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0
How to Profit from Suffering and Death (2)
2 MIN READ
0
MicroRNAs on Veteran’s Day 2019
< 1 MIN READ
0
The tipping point (revisited): 93K (2)
3 MIN READ
0
2020 National Vaccine Plan (1)
2 MIN READ
0
#SFN2019 to 2012: Hiding the facts (7)
2 MIN READ
0
Multigenerational epigenetic inheritance (3)
3 MIN READ
0
Patented Creation vs Evolution of Disease (9) 
4 MIN READ
0
Patented Creation vs Evolution of Disease (6)
4 MIN READ
0
Chemogenetic kinetics (7): DHA vs consensus (4)
3 MIN READ
0
Chemogenetic kinetics (7): DHA vs consensus (3)
3 MIN READ
0
Chemogenetic kinetics (4): Darwinism vs neo-Darwinism
2 MIN READ
0
Light-activated chemogenetic kinetics (2)
4 MIN READ
0
MicroRNA-mediated, since 1964 (1)
2 MIN READ
0
Lewis Thomas (revisited): 90K (7)
3 MIN READ
0
The tipping point (revisited): 90K (1)
4 MIN READ
0
Bastardized health care (4)
4 MIN READ
0
Relatable not debatable (1)
4 MIN READ
0
Kohl and Francoeur at 25 (8)
2 MIN READ
0
Virus-driven downsizing of the human brain (6)
6 MIN READ
0
DS Wilson’s view of biophysically constrained life (3)
3 MIN READ
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DS Wilson’s view of biophysically constrained life (2)
2 MIN READ
0
Ecological adaptation vs neo-Darwinian nonsense (5)
4 MIN READ
0
Do not call me Ishmael (2)
2 MIN READ
0
10,000 reasons to believe in biophysical constraints (revisited)
< 1 MIN READ
0
Light-activated continuous environmental tracking (2)
3 MIN READ
0
Light and life at base pair resolution (10)
4 MIN READ
0
Light and life at base pair resolution (5)
4 MIN READ
0
The tipping point (revisited): 81,000 publications (2)
2 MIN READ
0
The tipping point (revisited): 81,000 publications (1)
5 MIN READ
0
Hide and seek with science facts (7)
3 MIN READ
0
Hide and seek with science facts (2)
3 MIN READ
0
Electrons build fractal shapes and prevent lung cancer
2 MIN READ
0
Creation of an enzyme that kills theories (3)
8 MIN READ
0
Quantized energy-dependent microRNA-mediated autophagy (2)
< 1 MIN READ
0
Quantum initiation of cold chemistry vs Hypeology (2)
3 MIN READ
0
Quantum initiation of cold chemistry vs Hypeology (1)
4 MIN READ
0
Virus-driven genome engineering causes cancer?
2 MIN READ
0
The concept of a species (4)
2 MIN READ
0
The concept of a species (1)
2 MIN READ
0
The tipping point (revisited): 74,000 publications
4 MIN READ
0
Biologically uninformed science idiot: Self-defense (4)
4 MIN READ
0
Biologically uninformed science idiot: Self-defense (2)
3 MIN READ
0
From quantum physics to quantum souls (2)
2 MIN READ
0
Epigenetic inheritance of spatiotemporal regulation (3)
5 MIN READ
0
The eternal significance of microRNAs (5)
2 MIN READ
0
A single base change refutes theistic evolution (2)
2 MIN READ
0
Ecological adaptations vs the randomness of evolution (3)
4 MIN READ
0
EDAR V370A and sympatric speciation
2 MIN READ
0
Environmental selection is natural selection (5)
5 MIN READ
0
Environmental selection is natural selection
3 MIN READ
0
Abiogenesis vs microRNA biogenesis (3)
2 MIN READ
0
2018 March for Science vs microRNAs
7 MIN READ
0
The eternal significance of microRNAs (1) – revisited
2 MIN READ
0
The eternal significance of microRNAs (1)
< 1 MIN READ
0
Sympatric speciation vs pseudoscientic nonsense (2)
3 MIN READ
0
Part 3: Light-controlled cell biology (revisited)
3 MIN READ
0
Polymaths and paradigm shifts: from Asimov to Bear (3)
3 MIN READ
0
Ecological adaptation: a new definition of heredity (4)
4 MIN READ
0
Ecological adaptation: A new definition of heredity (3)
4 MIN READ
0
Ecological adaptation: A new definition of heredity (2)
2 MIN READ
0
MicroRNAs biophysically constrain behavior (2)
3 MIN READ
0
Creating biophysically constrained viral latency (1)
4 MIN READ
0
Conceptual critique: Innateness vs the death gene (1)
5 MIN READ
0
Subatomic: From thermophiles to humans (3)
3 MIN READ
0
Cryo-EM: Linking spatial and conformational constraints
9 MIN READ
0
A mental health problem at the highest level (3)
7 MIN READ
0
BiondVax Universal Flu Vaccine Patent
4 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (2)
6 MIN READ
0
Diet-driven RNA interference and cancer prevention (3)
6 MIN READ
0
Enzyme-constrained interethnic diversity (8)
< 1 MIN READ
0
Enzyme-constrained interethnic diversity (7)
6 MIN READ
0
Interethnic genetic similarities and differences (2)
4 MIN READ
0
Enzyme-constrained interethnic biodiversity (6)
8 MIN READ
0
Enzyme-constrained interethnic biodiversity (1)
5 MIN READ
0
Quantized energy-dependent viral trophism (2)
2 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (4)
11 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (2)
3 MIN READ
0
From base editing to RNA editing (6)
8 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (5)
4 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (3)
3 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (2)
4 MIN READ
0
The tipping point (revisited): 68,000 publications
5 MIN READ
0
Trump challenges the CDC to remember 9/11
14 MIN READ
0
Nature vs Science and Autophagy.pro
7 MIN READ
0
The overwhelming ignorance of sex researchers
5 MIN READ
0
Mouse morphs and primate diversity in 50 years
7 MIN READ
0
Light-activated error free DNA repair
5 MIN READ
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5 MIN READ
0
From base editing to RNA editing (5)
< 1 MIN READ
0
From base editing to RNA editing (2)
7 MIN READ
0
From base editing to RNA editing
2 MIN READ
0
Cryo-EM: More than a suggestion
< 1 MIN READ
0
Long-term adaptation replaces evolution (3)
6 MIN READ
0
Long-term adaptation replaces evolution (2)
2 MIN READ
0
Energy-dependent structure and function: Until death (3)
3 MIN READ
0
Energy-dependent structure and function: Until death (2)
5 MIN READ
0
Energy-dependent structure and function: Until death (1)
4 MIN READ
0
Cryo-EM from atoms to ecosystems
6 MIN READ
0
Entertaining yourself to death
6 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (6)
5 MIN READ
0
Criticisms of a validated model
9 MIN READ
0
Predicting who wins the 2017 Nobel Prizes
4 MIN READ
0
Inventing “Transcriptome Trajectory Turning Points”
2 MIN READ
0
Methylation and the Innate Immune System
< 1 MIN READ
0
MicroRNAs: Nature’s secret ingredient
2 MIN READ
0
The billion dollar baby (revisited)
3 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
Host-derived creation of all pathology (1 of 2)
5 MIN READ
0
An alternative mode of bacterial quorum sensing?
3 MIN READ
0
Your indifference is killing you and others
5 MIN READ
0
Your indifference is killing you and others (4)
4 MIN READ
0
The Origin of Information (4)
4 MIN READ
0
Can protein folding chemistry be understood by theorists?
5 MIN READ
0
Irreconcilable differences: food energy vs de novo assembly
2 MIN READ
0
New Testament Book Cover Refutes Theistic Evolution
7 MIN READ
0
Measuring energy vs human idiocy (social science)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (9)
3 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (6)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (1)
5 MIN READ
0
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
God’s shrinking role in salvation
8 MIN READ
0
MicroRNAs light up life
7 MIN READ
0
Infections and age change the odor of wine and people
4 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (2)
6 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models
7 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Food energy-dependent epigenetic adaptation
11 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (6)
8 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (3)
5 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
Dispensing with all pseudoscientific nonsense about evolution (2)
< 1 MIN READ
0
Feng Zhang refutes theistic evolution
4 MIN READ
0
Cytosis: Gameplay Runthrough
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Harvard researchers support young earth creationism
< 1 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Energy-dependent pheromone-controlled entropy (4)
3 MIN READ
0
The essence of precision medicine: drug targets or healthy longevity?
4 MIN READ
0
The essence of precision medicine
4 MIN READ
0
Allen Institute confirms food energy is information
6 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Theistic evolutionists fight back and lose (2)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Bill Gates refutes theistic evolution (prequel)
2 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (2)
2 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Anti-entropic energy and the “Music of Life”
3 MIN READ
0
Anti-entropic energy and the "Music of Life"
3 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
Dietary lutein and pheromone-controlled brain development
4 MIN READ
0
Re-inventing mutation-driven evolution (2)
4 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Explorers who do not know what is known
4 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
Happy biophysically constrained Thanksgiving (in the USA)
3 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence (2)
6 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
From Precis to Proof in 6000 years (3)
2 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Energy-dependent polycombic ecological adaptation
21 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
The natural success of RNAi and failed treatment
7 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Did evolution autophosphorylate your kinases?
5 MIN READ
1
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (3)
3 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Virus-driven energy theft: honeybee model
3 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
RNA methylation (2)
7 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Energy-dependent RNA methylation (9)
2 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (4)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
The tipping point? 50,000 publications (3)
6 MIN READ
0
Magic, Miracle, or Molecular Mechanism (2)
8 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (2)
7 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
MicroRNAs and/or QTLs: Who buried what?
2 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
A bumper crop of virus-infected weeds and people
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Genome-gate: Follow the money?
4 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
YEC compared to Perry Marshall’s opinions
4 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Energy-dependent purpose vs teleophobic telorexia
12 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
The toxic river of neo-Darwinian pseudoscience
3 MIN READ
0
Science vs semantics
4 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Bringing RNA back to epigenetics (20 years later)
11 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Despicable fools?
4 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
The unoffically uninvited
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Epigenetic (re)programming of behavior (2)
6 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
Ecological adaptations you cannot live without
6 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Innovative Neurotechnologies Link Sunlight to Precision Medicine
4 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
Sulfated steroids and RNA-mediated identity codes
< 1 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Life and death predicted by DNA methylation
3 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Rediscovering quantum behavior
2 MIN READ
0
Models are not theories (2)
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Unraveling the secrets of RNA-mediated events
2 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
Epigenetic inheritance of stress-perturbed protein folding
2 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Bird watchers and RNAs in cancers
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Microbes to humans 2015 Nobel Prize
2 MIN READ
0
Non-mainstream scientist shares Nobel prize in Medicine
3 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Theorists have not seen the light (2)
3 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Pathology: Eating and breathing viruses
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Multi-omic analysis features (SNPs, miRNA)
3 MIN READ
0
Somatic hypermutation vs RNA-mediated events
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Is life the balance between quantum and classical physics?
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
RNA-mediated X chromosome inactivation
3 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Information and communication
2 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
Eibi Nevo gets it wrong
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Olfaction & the octopus and human genomes
3 MIN READ
0
Thermodynamic constraints did not evolve
3 MIN READ
0
Protosuns, prebiotic molecules, proteins, and people
4 MIN READ
0
Mammalian-wide interspersed repeats (MIRs)
2 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (4)
3 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Light -induced nucleic acid-mediated gene duplication?
< 1 MIN READ
0
The stability of organized genomes
5 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Chromosomal rearrangements and domestication
3 MIN READ
0
Domestication via a single amino acid substitution
2 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2 MIN READ
0
Picornaviruses moving between primates (or not)
2 MIN READ
0
Faithfully repaired DNA
5 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
Becoming biologically informed
2 MIN READ
0
Celebrating independence from ridiculous theories
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
The sum of our RNA-mediated parts
2 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Iron, ferritin, thyroxine
2 MIN READ
0
Virus-driven death by evolutionary theory
3 MIN READ
0
“Evolution” of sex differences?
2 MIN READ
0
Nutrient stress-induced RNA-mediated pathology
< 1 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
Healthy mutants
2 MIN READ
0
Uniquely epigenomic gene regulation
2 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Physicians who practice evolutionary medicine?
3 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Vitamin B3 and DNA repair
4 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
The microbiome, pharmacogenetics, and privacy
< 1 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
Linking the origin of birds to dinosaurs
< 1 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Effect and affect of a single base-pair change
4 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
Viruses and cell type differentiation
3 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
Nutrient-dependent RNA interference (2)
4 MIN READ
0
Mutisensory integration: watching the paradigm shift
12 MIN READ
0
Origin of life and cancer (1,2,3)
2 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Too many targets for theories
3 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory (3)
4 MIN READ
3
Creating nothing but a theory (2)
4 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
The quantum / classical RNA-mediated ‘tipping point’
3 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Is DNA-directed transcription RNA-mediated?
2 MIN READ
0
What about birds?
5 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Are viruses microRNAs?
3 MIN READ
0
Sneaking up from behind
4 MIN READ
0
The future of physics predicts no future for evolutionary theory
3 MIN READ
0
Model organisms: the birds and the bees
3 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
0
There’s a model for that!
5 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
SNPs and millions of small variations in the human genome
3 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Pharmacogenomics
3 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2 MIN READ
2
Unassailable evidence vs assumptions
4 MIN READ
0
Forces of "Nature" limit dissemination of information
4 MIN READ
0
Systems biology and memory disorders
3 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Miracles are not miracles to evolutionary theorists
2 MIN READ
0
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
“Kardashians” in science
< 1 MIN READ
0
Can epigenetic inheritance occur without concurrent changes in morphology AND behavior?
3 MIN READ
0
Watching and waiting for more retractions
2 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
RNA-mediated events found everywhere
2 MIN READ
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
Nutrient-dependent erythropoiesis and anemia
6 MIN READ
0
Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
microRNAs and species relationships
3 MIN READ
0
Not focused and self-aggrandizing
2 MIN READ
0
The new light of chromosomal rearrangements
3 MIN READ
0
Chromosomal rearrangements and ecological adaptations
4 MIN READ
0
Targeting a cancer gene
2 MIN READ
0
Pulses of olfactory/pheromonal input
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Functional coding variants are not mutations
2 MIN READ
0
Mirror neurons and microRNA: theory vs biological facts
4 MIN READ
0
Are pheromones responsible for human body odour assessment?
2 MIN READ
0
A flawed model: no tripartate synapse in the adult brain
3 MIN READ
0
A newly discovered hypothalamic neurogenic niche in the brain
< 1 MIN READ
0
Pheromone-induced learning: a NEW model?
2 MIN READ
0
A Dictionary of Animal Behavior, Ecology and Evolution (excerpt)
2 MIN READ
0
Sex differences in Alzheimer's and everything else
2 MIN READ
0
The same neural mechanisms are at work in worms and humans
2 MIN READ
0
Pheromonemotionally speaking
2 MIN READ
0
Unconscious affects on incalculable genomic interactions
3 MIN READ
0
Woefully ignorant politicians and popular science
2 MIN READ
0
Human pheromones and autism spectrum disorders (2)
2 MIN READ
0
Human pheromones and diet-mediated life-extension
< 1 MIN READ
0
CB Nemeroff: Off Restriction
< 1 MIN READ
0
Human pheromones and autism spectrum disorders
2 MIN READ
0
Oxytocin for everything?
2 MIN READ
1
Pheromones and the “Bruce effect” in wild or domesticated horses and primates
2 MIN READ
0
Love is a receptor-mediated event: the pervasive influence of the late Robert L. Moss
3 MIN READ
0
How memory works
2 MIN READ
0
Pheromones and falling in love (circa 1974)
< 1 MIN READ
0
Pheromones, LH, neurogenesis, learning, memory, behavior
< 1 MIN READ
0