Energy-dependent epigenetic translation to mRNA stability (6)
(click to enlarge)
See: Energy-dependent epigenetic translation to mRNA stability (5) Five energy-dependent amino acid substitutions are linked to differences in RNA content and biodiversity in 4 mammalian species.
Species- and tissue-specific variation in mt-tRNA incorporation into the mt-LSU was analyzed…. Analysis of porcine dermal fibroblasts (C), human osteosarcoma 143B cells (D), bovine cardiac tissue (E), and rat hepatic tissue (F) depicts the relative abundance of each mt-tRNA across fractions (ImageQuant software); represented as a percentage of the total signal.
In my model, the metabolism of food to pheromones controls species specific and tissue specific variation in food energy-dependent mitochondrial transfer RNA (mt-tRNA) and the transgenerational epigenetic inheritance of morphological and behavioral phenotypes. In all models of biologically based cause and effect, the “RNA world” must be linked by metabolism to the pheromone-controlled fixation of RNA-mediated amino acid substitutions in supercoiled DNA. That is how the RNA world is linked from chromosomal rearrangements to energy-dependent RNA-mediated chromosomal inheritance and to protection from virus-driven energy theft, which links mutations to all pathology in species from microbes to humans.Nutrient-dependent/pheromone-controlled adaptive evolution: a model (published 2013 Jun 14)Mutation-Driven Evolution (also published 2013 Jun 14)Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization (published 2017 May 20)
…initiator-tRNA species proposed to participate in SOS reside in the cell nucleus, are found associated with supraspliceosomes (Table 2c), and appear not to be charged with an amino acid [87].
See also: Human mitochondrial ribosomes can switch their structural RNA composition
Our data demonstrate that only mt-tRNAVal or mt-tRNAPhe are found in the mitoribosomes of five different mammals, each mammal favors the same mt-tRNA in all tissue types, and strikingly, when steady-state levels of mt-tRNAVal are reduced, human mitoribosome biogenesis displays an adaptive response by switching to the incorporation of mt-tRNAPhe to generate translationally competent machinery.
The switches are food energy-dependent and they obviously link ecological variation to ecological adaptation via the Laws of Physics and basic principles of chemistry. In my model, for example, light-induced changes in hydrogen-atom transfer in DNA base pairs in solution cause initiator-transfer RNAs in the nucleus to become charged with an amino acid. Light energy-as-information subsequently appears to biophysically constrain all conditions of life in all living genera by protecting organized genomes from virus-driven energy theft and genomic entropy.Electron resonance pervades the brain
Using molecular modeling, the US-Canadian team of Travis Craddock, Stuart Hameroff and Jack Tuszynski had previously shown anesthetic binding in ‘quantum channels’, non-polar arrays of amino acid pi resonance clouds, winding through microtubules.
See also: What is life when it is not protected from virus driven entropy Energy as information and constrained endogenous RNA interference PARTICIPATION. OF GLYCOLYSIS. AND THE CITRIC ACID CYCLE. IN NUCLEAR ADENOSINE TRIPHOSPHATE SYNTHESIS
…thymus nuclei appear to have an endogenous substrate, and some experiments are presented which suggest that this substrate is probably not glycogen or glucose.
I do not know any pseudoscientist who has linked the energy-dependent creation of nucleic acid precursors to the energy-dependent creation of new genes, or to the activation of genes via the endogenous substrate. Indeed, the fact that there is an endogeneous substrate has been ignored, unless it has been replaced by an alternative fact which was somehow linked to all biodiversity via the physiology of reproduction.Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”
…Isolated thymus nuclei transport amino acids into an intranuclear pool by a process which seems to depend on energy from nuclear ATP synthesis (20).
See for comparison: A scientist named George Church has a wild idea to upend evolution — here’s what you should know about him
Darwin explained how species evolve. Church wants to turbocharge that process by putting new genes into organisms rather than waiting around for them to evolve those genes on their own.
Darwin did not explain how species evolve. Darwin presciently linked natural selection for food energy-dependent codon optimality to RNA-mediated amino acid substitutions and the physiology of reproduction, which biophysically constrains the hecatombic evolution of all pathology. Nothing known to serious scientists suggests that new genes “evolve.”
In between tRNA and CRISPR, Church coauthored hundreds of scientific papers, from “Predicting regulons and their cis-regulatory motifs by comparative genomics” to “Characterization of Cas9-guide RNA orthologs.”
After he characterized naturally occurring energy-dependent changes in RNA orthologs, George Church refuted neo-Darwinian evolutionary theories when he and others filed this patent application. RNA-Guided Human Genome Engineering
FIG. 3A-1 and FIG. 3A-2 depict a human codon-optimized version of the Cas9 protein and full sequence of the cas9 gene insert.
Human codon-optimized changes in proteins are energy-dependent, RNA-mediated, and the changes are biophysically constrained by the food that organisms eat and the physiology of reproduction in all living genera. That fact was placed into the context of the Structural diversity of supercoiled DNA in the context of this review: Feedback loops link odor and pheromone signaling with reproduction VIDEO
Richard Feynman was a Nobel prize winning Theoretical Physicist who popularized physics with his entertaining lecture style. This snippet is taken from one of his lectures in the series “The character of Physical Law” where he complains about all the different units that are used to measure the single concept of Energy.
See for comparison: George Church refutes theistic evolution
The future of genetic codes and BRAIN codes (video)
My comment on the video: Biophysically constrained genetic codes are brain codes. They link the epigenetic landscape to the physical landscape of supercoiled DNA via metabolic networks, which link energy as information to all cell type differentiation in all individuals of all living genera.
Virus-driven energy theft is linked from “gene vandalism” to epigenetically effected nutrient energy-as-information dependent RNA-mediated DNA repair.
Synthesis of nucleic acids became a “bigger deal” when Sutherland’s group showed that ultraviolet light was linked to the simultaneous de novo creation of nucleic acid precursors, which are the starting materials needed to make natural amino acids and lipids.
See also: Peter Godfrey Smith: “Other Minds: The Octopus, the Sea, and the Deep Origins…”
See for comparison:Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. ” — Kalevi KullRole of olfaction in Octopus vulgaris reproduction
Future work on O. vulgaris olfaction must also consider how animals acquire the odours detected by the olfactory organ and what kind of odour the olfactory organ perceives. The OL acting as control centre may be target organ for metabolic hormones such as leptin like and insulin like peptides, and olfactory organ could exert regulatory action on the OL via epigenetic effects of nutrients and pheromones on gene expression (Kohl, 2013; Elekonich and Robinson, 2000).
Her group also linked the conserved molecular mechanisms of chemical perception and gene expression in flies to consciousness in octopuses. See: Dose-Dependent Effects of the Clinical Anesthetic Isoflurane on Octopus vulgaris: A Contribution to Cephalopod Welfare via my model, albeit without citation to: Nutrient-dependent/pheromone-controlled adaptive evolution: a model or citation to Electron spin changes during general anesthesia in Drosophila. Riding the Evolution Paradigm Shift With Eugene Koonin
The entire evolution of the microbial world and the virus world, and the interaction between microbes and viruses and other life forms have been left out of the Modern Synthesis…
Virus-driven energy theft links the degradation of messenger RNA to all pathology, which is biophysically constrained by conserved molecular mechanisms that link food energy from viral latency to all energy-dependent healthy longevity.evolution game until everyone who is more than one decade old learns to play this game:
Cytosis: A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!
Cytosis 2 to 5 Players, Ages 10 +, Plays in 50 to 75 mins – (Shipping Aug/Sept 2017 – US, EU, CA & AU will ship from WITHIN their country / region)
See for comparison: How Statistics Weakened mRNA’s Predictive Power
More than 60,000 published works link food from energy-dependent changes in the microRNA/messenger RNA balance to differences in amino acid substitutions in mitochondrial transfer RNA (mt-tRNA).
The amino acid substitutions in different mammals appear to protect the mitochondria from virus-driven energy theft, which links the degradation of messenger RNA from mutations to all pathology.
The link from mt-tRNA to healthy longevity via species- and tissue-specific variation in the structure and function of supercoiled DNA may limit further consideration of neo-Darwinian theories because there is nothing to suggest that supercoiled DNA automagically evolved.
See for example: Figure 1
Species- and tissue-specific variation in mt-tRNA incorporation into the mt-LSU was analyzed…. Analysis of porcine dermal fibroblasts (C), human osteosarcoma 143B cells (D), bovine cardiac tissue (E), and rat hepatic tissue (F) depicts the relative abundance of each mt-tRNA across fractions (ImageQuant software); represented as a percentage of the total signal.
See also: Noncoding RNA Helps Cells Recover from DNA Damage
There is clear evidence that
femtosecond blasts of UV light repair DNA in the context of
energy-dependent changes in the microRNA/messenger RNA balance and autophagy , which protects all organized genomes from virus-driven energy theft and the
degradation of messenger RNA .
The failure to integrate the Nobel Prize winning works of Ben Feringa (Chemisty 2016) and Yoshinori Ohsumi (Physiology or Medicine 2016) prevents theorists from linking what organisms eat to their pheromone-controlled physiology of reproduction in the context of Schrodinger’s claims in “What is Life?”(1944) and this claim by Roger Penrose in the reprint edition:
How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy? (Roger Penrose 8 August 1991)
See also: From Fertilization to Adult Sexual Behavior In our section on molecular epigenetics, we wrote:
Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans…
The food energy that is linked from alternative splicing techniques of pre-mRNA to the chemistry of protein folding and the pheromone-controlled physiology of reproduction in all living genera seems to be largely ignored by those who are not Nobel Laureates.
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NSF’s parrot and other parrots
2
0
Complexity: Routes and Patterns (2)
< 1
0
Less evolvable RNA-mediated ecological adaptations
3
0
RNA-mediated nutritional psychiatry (2)
2
0
RNA-mediated nutritional psychiatry
4
0
Odor activation of ATP (2)
2
0
Part 3: Light-controlled cell biology (revisited)
3
0
Polymaths and paradigm shifts: From Asimov to Bear (5)
5
0
Polymaths and paradigm shifts: from Asimov to Bear (3)
3
0
Polymaths and paradigm shifts: from Asimov to Bear (2)
4
0
Polymaths and paradigm shifts: from Asimov to Bear (1)
5
0
How to create biologically uninformed theorists
7
0
Carl Zimmer refutes theistic evolution (2)
2
0
From photons to the proton motive force (2)
3
0
Ecological adaptation: a new definition of heredity (4)
4
0
Ecological adaptation: A new definition of heredity (3)
4
0
Ecological adaptation: A new definition of heredity (1)
5
0
MicroRNAs biophysically constrain behavior (2)
3
0
MicroRNAs biophysically constrain behavior
4
0
Creating biophysically constrained viral latency (2)
2
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (5)
2
0
Light-activated carbon fixation did not evolve (4)
7
0
The tipping point (revisited): 70,000 publications
4
0
George Church refutes theistic evolution (4)
4
0
Conceptual critique: Innateness vs the death gene (2)
5
0
Conceptual critique: Innateness vs the death gene (1)
5
0
How to biophysically constrain the flu virus (1)
4
0
Subatomic: From thermophiles to humans (3)
3
0
Cryo-EM: Linking spatial and conformational constraints
9
0
A reversible TCA cycle in a thermophile (3)
4
0
A reversible TCA cycle in a thermophile
5
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (4)
8
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (3)
6
1
The MicroRNAome Strikes Back: A Sokalian hoax (10)
3
0
BiondVax Universal Flu Vaccine Patent
4
0
The MicroRNAome Strikes Back: A Sokalian hoax (6)
4
0
The MicroRNAome Strikes Back: A Sokalian hoax (2)
6
0
The MicroRNAome Strikes Back: A Sokalian hoax (1)
4
0
A mental health problem at the highest level (2)
3
0
Diet-driven RNA interference and cancer prevention (3)
6
0
Autophagy is the antiphage defense strategy (2)
4
0
Enzyme-constrained interethnic diversity (8)
< 1
0
Enzyme-constrained interethnic diversity (7)
6
0
Diet-driven RNA interference and cancer prevention
5
0
Enzyme-constrained interethnic biodiversity (1)
5
0
A Mathematical Model Links Quantum Physics to Quantum Souls (2)
4
0
The “walking fish” walks straight from quantum physics to quantum souls (4)
11
0
The “walking fish” walks straight from quantum physics to quantum souls (2)
3
0
The “walking fish” walks straight from quantum physics to quantum souls
6
0
A Mathematical Model Links Quantum Physics to Quantum Souls (1)
6
0
From base editing to RNA editing (6)
8
0
From nitrogen atoms to ecosystems in all living genera
6
0
Energy-dependent base editing and correction of mutations (3)
3
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (3)
3
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (2)
4
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (1)
3
0
Darwinian adaptation: a clear evolutionary trail?
4
0
Agilent technology and energy-dependent autophagy
8
0
Trump challenges the CDC to remember 9/11
14
0
Elsevier fails to support the concept of autophagy
4
0
From Autophagy.pro (transitions)
4
0
Nature vs Science and Autophagy.pro
7
0
Autophagy.pro vs Nature Publications Group
2
0
The overwhelming ignorance of sex researchers (2)
4
0
Energy-dependent base editing and correction of mutations (2)
9
0
Trashing the 2nd Law
7
0
The overwhelming ignorance of sex researchers
5
0
Mouse morphs and primate diversity in 50 years
7
0
Two retractions of human idiocy
2
0
Who created your virus-driven death gene? (1)
5
0
Schrodinger’s answer to Schrodinger’s question
3
0
MicroRNAs and the Cassandra syndrome (revisited)
4
0
Light-activated error free DNA repair
5
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5
0
Pheromones biophysically constrain base editing and RNA editing
3
0
From base editing to RNA editing (4)
5
0
The next reformation: 500 years too late? (1)
< 1
0
The next reformation: 500 years too late? (2)
2
0
The next reformation: 500 years too late? (3)
5
0
From base editing to RNA editing (2)
7
0
From base editing to RNA editing
2
0
Loss of energy as information (1)
3
0
Cryo-EM: More than a suggestion
< 1
0
Long-term adaptation replaces evolution (3)
6
0
Long-term adaptation replaces evolution (2)
2
0
Losers: rediscovering an epigenetic key
2
0
Virulence: Out of stock
2
0
Faith in evolution: Paleontology as a molecular science
5
0
Energy-dependent structure and function: Until death (5)
4
0
Energy-dependent structure and function: Until death (3)
3
0
Energy-dependent structure and function: Until death (2)
5
0
Energy-dependent structure and function: Until death (1)
4
0
Until death: Virus-driven failure of multisensory integration (2)
6
0
Cryo-EM from atoms to ecosystems
6
0
Predicting who wins the 2017 Nobel Prizes (7)
4
0
Entertaining yourself to death
6
0
Criticisms of a validated model
9
0
Predicting who wins the 2017 Nobel Prizes (5)
2
0
Predicting who wins the 2017 Nobel Prizes (4)
4
0
Thanks again for asking about DNA methylation
4
0
Predicting who wins the 2017 Nobel Prizes (3)
2
0
Predicting who wins the 2017 Nobel Prizes (2)
4
0
Predicting who wins the 2017 Nobel Prizes
4
0
1996-2016: Ignoring alternative splicings of pre-mRNA
7
0
Life and death via chemical effects on photosynthesis
8
0
Inventing “Transcriptome Trajectory Turning Points”
2
0
Methylation and the Innate Immune System
< 1
0
The billion dollar baby (revisited)
3
0
Sexual communication signals: New Insights!
10
0
Quantum physics, Patrick Bateson, and neo-Darwinian nonsense
3
0
Neurosteroids revisited two decades later
3
0
Host-derived creation of all pathology (2 of 2)
9
0
God vs host-derived creation of virus-driven pathology (2)
4
0
God vs host-derived creation of virus-driven pathology
6
0
An alternative mode of bacterial quorum sensing?
3
0
Pseudoscientists hate what science explains! (3)
4
0
Energy and neural plasticity
< 1
0
Your indifference is killing you and others
5
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4
0
The Origin of Information (4)
4
0
New Testament Book Cover Refutes Theistic Evolution
7
0
Measuring energy vs human idiocy (social science)
2
0
Energy-dependent physical and biophysical constraints (9)
3
0
Energy-dependent physical and biophysical constraints (8)
5
0
Energy-dependent physical and biophysical constraints (7)
2
0
Energy-dependent physical and biophysical constraints (6)
8
0
Energy-dependent physical and biophysical constraints (5)
7
0
Energy-dependent physical and biophysical constraints (4)
2
0
Energy-dependent physical and biophysical constraints (2)
4
0
Energy-dependent physical and biophysical constraints (1)
5
0
Cell type assembly and the space-time continuum
2
0
Richard P. Feynman refuted theistic evolution
5
0
Epigenetic effects of stress by Bruce McEwen (1)
9
1
The emergence of light as energy from a life-giving star
11
2
God’s shrinking role in salvation (3)
9
0
God's shrinking role in salvation (3)
9
0
MicroRNAs GnRH and the failure of sex research
7
0
God’s shrinking role in salvation (2)
5
0
God’s shrinking role in salvation
8
0
Food energy-dependent cell type differentiation (2)
10
0
Hard Science vs the neo-Darwinian “magic box”
9
0
Infections and age change the odor of wine and people
4
0
From E. coli to monkeys and mankind: Theories vs models (2)
6
0
From E. coli to monkeys and mankind: Theories vs models
7
0
Food energy-dependent epigenetic adaptation (3)
3
0
Food energy-dependent epigenetic adaptation (2)
< 1
0
Food energy-dependent epigenetic adaptation
11
0
Energy-dependent epigenetic translation to mRNA stability (5)
4
0
Energy-dependent epigenetic translation to mRNA stability (4)
2
0
Energy-dependent epigenetic translation to mRNA stability (3)
5
0
Energy-dependent epigenetic translation to mRNA stability
8
0
UV light and non-coding RNA
2
0
Nothing evolved into all biodiversity on Earth
4
0
Energy as information and constrained endogenous RNA interference (4)
7
0
What energy source do proteins prefer?
6
0
Energy-dependent microRNA biogenesis
4
0
Draining the academic swamp of parasites
3
0
The death of human ethology via ecology
7
0
Ignoring peer review, ATP, and microRNA biosynthesis
5
0
The death of CRISPR; long live endogenous RNAi
5
0
Dispensing with all pseudoscientific nonsense about evolution (2)
< 1
0
Dispensing with March for Science Dispatches (2)
2
0
Dispensing with March for Science Dispatches (1)
2
0
The Virus-Driven Suicide March for Science
5
0
Virus-driven downsizing of the human brain (4)
2
0
March for science vs microRNAs
3
0
Feng Zhang refutes theistic evolution
4
0
Open Science: Closed to facts about microRNAs
6
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3
0
Viruses in pathogenic variants disrupt alternative splicings
2
0
Respiration-dependent endogenous RNA interference
4
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3
0
Synthetic RNA-based switches
2
0
Sunlight bursts the social bubble of physics and math
3
0
Functionally interdependent editing and methylation
4
0
Cytosis: Biology Content
7
0
Light-activated feedback loops vs self-organization of ecosystems
7
0
Harvard researchers support young earth creationism
< 1
0
Cytosis: A Cell Biology Board Game
< 1
0
Sal Giardina: apologetics revisited
8
0
Life in your UV light-constrained galaxy
5
0
Who will kill the billion dollar baby? Bill Gates or Donald Trump
3
0
Thinking about energy is not radical re-thinking
6
0
Food for thought: Penrose v Ellis (1)
5
0
Energy-dependent pheromone-controlled entropy (4)
3
0
Proof: Sunlight is energy as information
< 1
0
Energy-dependent pheromone-controlled entropy (2)
6
0
Energy-dependent pheromone-controlled entropy (1)
4
0
The essence of precision medicine: drug targets or healthy longevity?
4
0
The essence of precision medicine
4
0
Allen Institute confirms food energy is information
6
0
RNA-mediated adult learning, memory, and neurogenesis
3
0
Energy-dependent allelic imbalances, viruses, and pathology
3
0
March for Science (revisited)
3
0
Theistic evolutionists fight back and lose (3)
4
0
Theistic evolutionists fight back and lose (2)
4
0
Theistic evolutionists fight back and lose
4
0
Young earth creationists refute theistic evolution
3
0
Charles Darwin refutes theistic evolution
2
0
Bill Gates refutes theistic evolution (prequel)
2
0
Bill Gates refutes theistic evolution (sequel)
8
0
Bill Gates refutes theistic evolution
4
0
Emily Witkin refutes theistic evolution
2
0
Wikipedia refutes theistic evolution
4
0
RNA editing refutes theistic evolution
4
0
Serious scientists refute theistic evolution again
3
0
Pseudoscientists fail to refute theistic evolution
4
0
Stuart Kauffman refutes theistic evolution
3
0
May the anti-entropic force of sunlight be with you
4
0
Francis S. Collins refutes theistic evolution
6
0
Energy is information. Objections over ruled. You’re fired!
7
0
Happy Darwin Day (2017)
4
0
George Church refutes theistic evolution (3)
5
0
George Church refutes theistic evolution (2)
2
0
George Church refutes theistic evolution
5
0
Natural selection for codon optimality and quantum viruses
5
0
Physicists: Desperate Acts (revisited)
6
0
Energy as information and constrained endogenous RNA interference (3)
4
0
Energy as information and constrained endogenous RNA interference (2)
2
0
Fighting for virus-driven pathology
5
0
ATP-dependent creation of RNA
2
0
Dobzhansky 1973 and precision medicine (5)
3
0
Dobzhansky 1973 and precision medicine (4)
5
0
Dobzhansky 1973 and precision medicine (3)
5
0
Atomic theory vs facts about hydrogen-atom transfer
4
0
Dobzhansky 1973 and Precision Medicine (2)
5
0
Trump’s appeal to common sense (2)
3
0
Trump’s appeal to common sense
2
0
Science journalists or paid propagandists? (4)
6
0
Dobzhansky 1973 and precision medicine
6
0
Twisted theories and weaponized facts
3
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6
0
Critical values expose virus-driven energy theft (2)
4
0
Theorists sell hidden energy (2)
4
0
Critical values expose virus-driven energy theft
6
0
Theorists sell hidden energy
3
0
Anti-entropic energy and the “Music of Life”
3
0
Anti-entropic energy and the "Music of Life"
3
0
Evolved patterns of brain stimulation
3
0
Chirality is reality
6
0
Energy-dependent hydrogen bonds in supercoiled DNA
7
0
Energy-dependent chirality (2)
3
0
Energy-dependent chirality
6
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5
0
Vietnam Veterans and others with glioblastoma
3
0
Energy-dependent sensory maps (1996-2016)
5
0
Energy-dependent alternative splicings 1996 – 2016
12
0
Energy-dependent oscillating gene networks organize life
4
0
2016 obfuscated facts about energy as information
5
0
More refutations of neo-Darwinian nonsense
7
0
Re-inventing mutation-driven evolution (2)
4
0
Re-inventing mutation-driven evolution
3
0
Sudden death indel polymorphism
4
0
Anti-entropic virucidal energy as information
10
0
Bio-functional information
3
0
Bird-brained theorists
< 1
0
Expunging the distinguished public
2
0
Explorers who do not know what is known (2)
6
0
Explorers who do not know what is known
4
0
Autophagy is the antiphage defense strategy
3
0
Energy-dependent de novo creation and neurogenesis (2)
5
0
Energy-dependent de novo creation and neurogenesis
7
0
Theories vs facts about polycombic adaptation
3
0
Tasting light links energy from creation to adaptation
9
0
Politicized science: The demise of RNA-mediated.com?
3
0
Combating evolution: Battlefield medicine vs politicized science
6
0
The futility of The Battlefield FB group
10
0
Metabolic Phenotyping Research
2
0
Phylogenetic similarity sans energy
2
0
Happy biophysically constrained Thanksgiving (in the USA)
3
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4
0
Light, behavior and autophagy, a gender-specific risk factor
4
0
Controlled amino acid treatment of all pathology
4
0
Energy-dependent purifying selection / autophagy (2)
2
0
Energy-dependent purifying selection / autophagy (4)
2
0
Energy-dependent purifying selection / autophagy (5)
2
0
Energy-dependent purifying selection / autophagy (6)
3
0
Energy-dependent purifying selection / autophagy
2
0
Optogenetics: Let there be virucidal light!
2
0
Base pairs, amino acids and phenotypes
10
0
Survivors of RNA-mediated terrorism
5
0
RNA-mediated terrorism
< 1
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3
0
Building delicious base pairs in class. It's elementary Watson and Crick
3
0
Energy-dependent maternal-to-zygotic transition
6
1
Virus-driven mutation or amino acid substitution
5
0
Epigenetically effected energy-dependent fluorescence (2)
6
0
Epigenetically effected energy-dependent fluorescence
5
0
Epigenetics and autophagy vs mutations and evolution (7)
3
0
Epigenetics and autophagy vs mutations and evolution (2)
2
0
Epigenetics and autophagy vs mutations and evolution
< 1
0
From Precis to Proof in 6000 years (3)
2
0
From Precis to Proof in 6000 years (2)
5
0
Coulombic interactions facilitate polycombic adaptation
5
0
Top-down adaptation vs bottom-up evolution
6
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1
0
Polycombic ecological adaptation as a science, not a theory (2)
12
0
Demoncrats fight polycombic ecological adaptation
4
0
Polycombic ecological adaptation as a science, not a theory
3
0
Biological evolution as a philosophy, not a science
6
0
Attacking Young Earth Creationists
5
0
Olfactory receptor pseudo-pseudogenes
2
0
80 years of causal analysis (1936 – 2016)
11
0
Did evolution autophosphorylate your kinases? (3)
2
1
The human virome (revisited)
4
0
Carl Woese was wrong
2
0
The natural success of RNAi and failed treatment
7
0
Pheromone-controlled autophagy
4
0
Hecatombic evolution VS polycombic ecological adaptation
3
0
Virus-mediated hecatombic evolution
2
0
Hecatombic evolution via oncocers and oncohistones
9
0
Did evolution autophosphorylate your kinases? (2)
5
1
Nutrient-dependent autophagy
3
0
The last RNA-mediated theory killer (2)
7
0
Life is energy-dependent task management (4)
2
0
Life is energy-dependent task management (2)
3
0
Life is energy-dependent task management
3
0
Hypothesis free pseudoscience vs facts (5)
6
0
Hypothesis free pseudoscience vs facts (4)
5
0
Hypothesis free pseudoscience vs facts (3)
3
0
Hypothesis free pseudoscience vs facts (2)
5
0
Hypothesis free pseudoscience vs facts (1)
5
0
The last RNA-mediated theory killer
< 1
0
Chromatin: The structure of DNA (3)
4
0
Chromatin: The structure of DNA
6
0
Consciousness is simply food rearranged
2
0
Hydrogen-atom energy in DNA base pairs
6
0
DNA repair via junk DNA (2)
5
0
The Aquatic Ape / Waterside Ape divergence
6
0
Light energy-dependent active motifs
6
0
Light energy-induced base pair changes (2)
4
0
Light energy-induced base pair changes (1)
6
0
Displays of ecological adaptation (2)
3
0
DNA repair via junk DNA (1)
5
0
Displays of ecological adaptation
2
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4
0
Virus-driven energy theft causes cancer
2
0
Linking RNA structure to function
3
0
Exosomes, Inflammatory Disease, Pathogenesis, Treatment
< 1
0
How did the innate immune system evolve?
4
0
Plant microRNAs slow virus-driven aging
3
0
Protecting 4 billion people from virus-driven entropy
< 1
0
Increased soil pH and nutrient availability
4
0
Energy-dependent cellular communication
3
0
Lawless evolution: No physics
4
0
Conserved biophotonic emissions
7
2
Virus-driven energy theft: honeybee model
3
0
Antithetical conclusions (7)
3
0
Antithetical conclusions (5)
4
0
Antithetical conclusions (6)
3
0
Antithetical conclusions (4)
3
0
Anthetical conclusions (2)
5
0
RNAi: From magic bullet to billion dollar baby
4
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4
0
Energy-dependent natural fluorescence and bioluminescence
2
0
Pseudoscientists ignore what serious scientists prove
6
0
Biophysically constrained cell type differentiation
3
0
Food supplement or licensed immunostimulant?
6
0
Virus-driven downsizing of the human brain (3)
4
0
Do weak bosons evolve into leptons?
4
0
Q and A: Energy-dependent cell type differentiation
10
0
Biophotonics, glycobiology, quantized biodiversity (2)
19
0
The end of neo-Darwinism
5
0
Biophotonics, glycobiology, quantized biodiversity
4
0
The Origin of Information (2)
6
0
The tipping point? 50,000 publications (5)
3
0
Did “Nature” kill Steve Jobs? (3)
10
0
Invisible dark matter
< 1
0
Funding the Human Genome Project-Write
2
0
Did “Nature” kill Steve Jobs?
3
0
Virus-driven downsizing of the human brain (2)
< 1
0
RNA methylation (revisited)
< 1
0
Placing boundaries where none exist
< 1
0
Virus-driven downsizing of the human brain
2
0
MicroRNAs and sexual orientation
8
0
RNA methylation, learning, memory and behavior,
< 1
0
Innate immunity and multiplexing
7
0
RNA methylation (2)
7
0
Amino acids and virus penetration
3
0
Major transition ends use of silly theories
5
0
RNA methylation
2
0
Model vs theory: Progress report!
8
0
Masters of deception about nature (2)
7
0
Masters of deception about nature
8
0
The Mind’s Eyes (revisited)
10
0
Cracking the Olfactory Code?
5
0
RNA methylation, behavior, and disease
6
0
Modelling life scientifically: RNA-mediated events
12
0
Energy-dependent RNA methylation (9)
2
0
Energy-dependent RNA methylation (10)
4
0
Energy-dependent RNA methylation (8)
4
0
Energy-dependent RNA methylation (7)
7
0
Energy-dependent RNA methylation (5)
3
0
Energy-dependent RNA methylation (4)
5
0
Energy-dependent RNA methylation (3)
10
0
Energy-dependent RNA methylation (2)
5
0
Energy-dependent RNA methylation (1)
6
0
Secular humanism and ecoterrorism
4
0
Thermotolerance and longevity (2)
3
0
War Games: False Flag Terrorism (2)
4
0
War Games: False Flag Terrorism
5
0
Virus-driven energy theft: definition?
5
0
Energy-dependent biodiversity (4)
4
0
The tipping point? 50,000 publications (4)
3
0
Energy-dependent biodiversity (2)
2
0
Neo-Darwinism failed in 1995
3
0
Countdown to Genetics and Genomics
< 1
0
Magic, Miracle, or Molecular Mechanism (2)
8
0
Energy-dependent creation and entropy
4
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5
0
RNA-mediated physics, chemistry, and molecular epigenetics
9
0
Wasted Templeton Funding (4)
3
0
MicroRNAs and/or QTLs: Who buried what?
2
0
RNA splicing, genetic variation, and disease
2
0
Wasted Templeton Funding (3)
2
0
Wasted Templeton Funding (2)
2
0
Millions of water molecules vs years of evolution
2
0
From nothing to life and death everywhere
5
0
Molecular Diagnostics: What is unprotected life? (5)
5
0
Molecular Diagnostics: What is unprotected life (4)
2
0
Molecular Diagnostics: What is unprotected life (3)
5
0
Genome-gate: Follow the money?
4
0
Molecular Diagnostics: What is unprotected life? (2)
7
0
Molecular Diagnostics: What is unprotected life?
2
0
Virus-driven sex differences?
2
0
Ricki Lewis’ Time Machine (4)
8
0
Creating and/or programming the immune system
< 1
0
Half truths support theories without facts
4
0
Ricki Lewis’ Time Machine (3)
5
0
Creating nutrient-dependent life with enough genes to survive
3
0
Confusing effects and affects of visual input
2
0
Ignore the evidence: Rachel Feltman
5
0
Energy-dependent purpose vs teleophobic telorexia
12
0
Virus-driven disorder prevention and health promotion
6
0
Stress-linked population-level history dependence
5
0
Jay R. Feierman: twenty years of antagonism
5
0
Energy dependent RNA-mediated immunity (6)
5
0
Do not miss the misrepresentations
2
0
Energy dependent RNA-mediated immunity (5)
4
0
Energy dependent RNA-mediated immunity (4)
6
0
Energy dependent RNA-mediated immunity (3)
8
0
Energy dependent RNA-mediated immunity (2)
10
0
RNA-mediated DNA modifications
5
0
Science vs semantics
4
0
From angstroms to ecosystems and entropy
2
0
Bacteria see the light and they adapt (2)
5
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3
0
Bringing RNA back to epigenetics (20 years later)
11
0
Effects on invertebrate GnRH and affects on primate behavior
6
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2
0
Hydrogen-atom transfer in DNA base pairs (7)
5
0
Bacteria see the light and they adapt
7
0
The Light and Darkness of “Evolution 2.0”
11
0
Will modern human populations adapt to the Zika virus?
5
0
Organic Compounds and the Miracle of Smell and Taste
7
0
Ricki Lewis’ Time Machine (2)
6
0
Ricki Lewis’ Time Machine
5
0
Virus-perturbed alternative splicings
3
0
Hydrogen-atom transfer in DNA base pairs (5)
10
0
The radical pair mechanism of ecological speciation
3
0
Origin and evolution of the genetic code
2
0
The unoffically uninvited
3
0
Blood test links atoms to ecosystems
2
0
Juvenile hormone links atoms to ecosystems
3
0
Teleophobes vs teleophiles: a recent history
2
0
Ecological genomics: teleophobes respond (too late)
10
0
Genes, orchid odors, and pheromones from blonds
5
0
MicroRNA-mediated RNA epigenetics
2
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3
0
Finding peace and π in the light of H bond energy
5
0
Epigenetic (re)programming of behavior (3)
5
0
Perry Marshall: too much information for atheist PZ Myers
3
0
Epigenetic (re)programming of behavior (2)
6
0
Epigenetic (re)programming of behavior
4
0
NORAD: air defense and defense against genomic entropy
7
0
Life history transitions and RNA-mediated survial
2
0
Did Dobzhansky see the UV light of creation?
10
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5
0
Does metabolism link beneficial mutations to cancer?
10
0
Hydrogen-Atom Transfer in DNA Base Pairs (3)
3
0
Manufacturing fossil “evidence”
4
0
RNA-mediated theory killers (4)
9
0
RNA-mediated theory killers (2)
8
0
A two-faced protein enables RNA-mediated DNA repair (4)
6
0
A two-faced protein enables RNA-mediated DNA repair (3)
8
0
MicroRNAs vs Red Queen hypothesis
4
0
The Sherlock lab: Beneficial mutations
5
0
Neo-Darwinism vs the neocortex
4
0
A two-faced protein enables RNA-mediated DNA repair
2
0
Life and death predicted by DNA methylation
3
0
Positive feedback loops and epigenetic traps
2
0
Stress-perturbed mitochondrial dysfunction (2)
5
0
Behavioral Immune System model
4
0
Theorists can’t understand biology
6
0
Neuroplasticity
4
0
Too complex for the Complex Biological Systems Alliance
4
0
Receptor methylation controls behavior
2
0
Virus, transposon and plasmid evolution
< 1
0
Conserved molecular mechanisms
< 1
0
Models are not theories (2)
2
0
Fossils vs cell types and the brain
3
0
Cyclic cosmology and the stability of organized genomes
4
0
eQTLs and ecological adaptation
< 1
0
Unraveling the secrets of RNA-mediated events
2
0
Designing, engineering, and protecting biodiversity
3
0
The virome, microbiome, replisome and supercoiled DNA
2
0
Skip the politics; embrace the facts
5
0
Human pheromone deniers: What’s next?
5
0
700 million years of evolution?
5
0
Biophysically constrained or unconstrained?
2
0
Mutated mitochondrial genes vs Supercoiled DNA
2
0
RNA-mediated retrotransposon-mediated biodiversity
3
0
Mystery machine vs model (2)
2
0
Mystery machine vs medical intelligence
2
0
Xist-ing on planet Earth
2
0
Preventing genomic entropy
4
0
Energy and evolution: another opinion?
2
0
Supercoiled DNA constrains virus-driven genomic entropy
2
0
Let there be anti-entropic light (2)
4
0
Foundamentals of theory
4
0
Microbes to humans 2015 Nobel Prize
2
0
Non-mainstream scientist shares Nobel prize in Medicine
3
0
Is mainstream science in “Science” pseudoscience?
5
0
Mechanisms of stress: from genes to cancer
9
0
Viruses come alive: Tree of life pseudoscience
6
0
Theorists have not seen the light (2)
3
0
Hijacked light energy and vertebrate pathology
4
0
Theorists have not seen the light
4
0
Alternative pre-mRNA splicing and ecological adaptation
7
0
Pathology: Eating and breathing viruses
2
0
Exosomes and the RNA-mediated future of medicine
5
0
Multi-omic analysis features (SNPs, miRNA)
3
0
Somatic hypermutation vs RNA-mediated events
2
0
Phytochemical link from the sun to cell types
2
0
New anti-entropic microbes
3
0
Genome sequencing, cadherins, and quantum consciousness
6
0
“New” quantum biology. Pirating the old
3
0
Cell types, SNVs, CNVs, and chromosomes
3
0
Thermotolerance and Longevity
57
0
RNA-mediated permanent symbioses
11
0
Is life the balance between quantum and classical physics?
3
0
Anti-entropic containment of energy: symbiosis 1.0
5
0
Atomic-resolution of cell type signaling
4
0
Information and communication (2)
6
0
Information and communication
2
0
From “Blood Music” to Evolution 2.0
5
0
Olfaction & the octopus and human genomes (2)
4
0
Olfaction & the octopus and human genomes
3
0
Thermodynamic constraints did not evolve
3
0
Protosuns, prebiotic molecules, proteins, and people
4
0
Mammalian-wide interspersed repeats (MIRs)
2
0
Ecological speciation vs revised evolutionary syntheses
6
0
Ecology replaces the extended evolutionary synthesis
4
0
The stability of organized genomes (4)
3
0
The stability of organized genomes (3)
3
0
Epimutation.com: a domain of confusion
8
0
Light -induced nucleic acid-mediated gene duplication?
< 1
0
The stability of organized genomes
5
0
Viruses, amino acids, and somatic cell types (2)
5
0
RNA-mediated terms of virus-induced en-deer-ment
2
0
Domestication via a single amino acid substitution
2
0
Becoming biologically informed (3)
3
0
Easy editing: Reinventing our RNA world
3
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2
0
Picornaviruses moving between primates (or not)
2
0
Riding the wrong direction
3
0
Faithfully repaired DNA
5
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6
0
MicroRNA controlled growth and brain development
7
0
MicroRNA – controlled ecological adaptations
5
0
Becoming biologically informed
2
0
Celebrating independence from ridiculous theories
3
0
“New” epigenetic mechanism for lifelong learning?
3
0
The sum of our RNA-mediated parts
2
0
Protein folding and Google page rank
2
0
Iron, ferritin, thyroxine
2
0
Virus-driven death by evolutionary theory
3
0
“Evolution” of sex differences?
2
0
Nutrient stress-induced RNA-mediated pathology
< 1
0
Amino acid substitutions are not mutations
2
0
What I cannot create I eliminate from discussion
3
0
RNA-mediated development
2
0
Healthy mutants
2
0
Uniquely epigenomic gene regulation
2
0
Unknown mechanisms and conclusions
2
0
Alternative splicings: epigenetics meets pharmacogenomics
4
0
Epigenetic regulation of aging by glycine and GnRH
5
0
Physicians who practice evolutionary medicine?
3
0
Pattern recognition: biogeochemical structure and function
5
0
Viruses and the human-like microbiome
3
0
Informing the biologically uninformed
< 1
0
I forgot. How do mutations cause evolution?
4
0
One amino acid substitution, genes, and brain activity
3
0
Batch effect vs epigenetic effects
3
0
Gene expression, immortality, and cancer
6
0
Scientists lose. A sci-fi author gains credibility
2
0
Vitamin B3 and DNA repair
4
0
Bees and primates automagically evolve
3
0
Ignoring systems complexity (it’s too complicated)
3
0
Virus-driven cancer treatment and prevention
2
0
The microbiome, pharmacogenetics, and privacy
< 1
0
A special issue on nutritional epigenetics
5
0
Retinoic acid + one receptor regulate the genome
3
0
Epigenetics: microRNAs effect an integrative pathway
4
0
Protein isoforms do not evolve
3
0
Tissue type variation and expression of genes
< 1
0
From gut bacteria to breast milk and back
5
0
Chance mutations — not natural selection
5
0
Viruses in gut microbes
4
0
How to find a “holy grail” under your nose
3
0
Physics, chemistry, light, and life
2
0
MicroRNAs and the exposome (2)
< 1
0
MicroRNAs and the exposome
5
0
Epigenetics vs the fossil record
4
0
An epigenetic mark links algae, worms, and flies
2
0
Effect and affect of a single base-pair change
4
0
Thermodynamics and protein folding landscapes
2
0
RNA-mediated silencing of a chromosome
3
0
Feedback loops link insects to human brains
2
0
Viruses and cell type differentiation
3
0
RNA-mediated cell types and precision medicine
5
0
DNA Methylation and organized genomes
7
0
Misunderstanding cancer
7
0
Amino acid-dependent cell type differentiation
8
0
Nutrient-dependent RNA interference (2)
4
0
Mutisensory integration: watching the paradigm shift
12
0
Origin of life and cancer (1,2,3)
2
0
Silencing genes and serious scientists
3
0
The miRNA/mRNA balance: a suboptimal strategy?
2
0
Nutrient-dependent microRNAs control cell types
6
0
Life: conserved ion and amino acid transporters
3
0
Too many targets for theories
3
0
Creating nothing but a theory (3)
4
3
Creating nothing but a theory (2)
4
0
Viruses and ecologically adapted animals
2
0
The quantum / classical RNA-mediated ‘tipping point’
3
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4
0
Quantum correlations/pseudoscience
3
0
Anti-entropic solar energy
5
0
Mimicking claims and ignoring facts
4
0
Correctly modeling biological energy
2
0
Questions about life’s diversity
21
0
RNA-directed gene choice
5
0
Epigenetics Skeptism
5
0
Is DNA-directed transcription RNA-mediated?
2
0
What about birds?
5
0
RNA directed DNA methylation and cell types
4
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2
0
From 3-D to epigenetically-effected 4-D genome make-up
5
0
Let there be anti-entropic light (1)
11
0
An epigenetic trap (the prequel)
5
0
What if Darwin was not still dead?
2
0
Constrained evolution is ecological adaptation
5
0
From Hydra to humans vs a Lakatosian research program
4
0
Communication, not mutations
2
0
Models by evolutionary biologists are not models
2
0
The future of physics predicts no future for evolutionary theory
3
0
Dual genomes: exposing the evolution industry
5
0
Epigenetic pharmacology and RNA-mediated transciptional landscapes
3
0
More than a bag of chemicals?
2
0
Intelligent viruses and cancers?
10
0
Complex behaviors of cell types in cancer
6
0
RNA eclipses the importance of DNA to cell type differentiation
4
0
Pharmacogenomics
3
0
It’s cell type differention, not cell fate determination (2)
3
0
Are evolutionary theorists 'nob ends'?
5
2
No understanding of biodiversity
2
0
Behavioral ecology: please continue to believe in our fantasies
3
0
RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2
2
Color vision refutes the evolutionary dogma of gene duplication
4
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2
0
RNA-mediated cell type differentiation and behavior
3
0
Probable changes in connectivity
2
0
Memory of repression and memory of behavior
2
0
RNA-mediated species diversification from microbes to primates
3
0
Genotype, observed phenotype, and distinctly disordered behaviors
3
0
RNA-mediated ecological adaptation is not evolution
2
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4
0
Pattern recognition and conserved receptors (TAARs)
5
0
A relatively young branch of science called epigenetics
4
0
Insect homology and diversity attributed to mutations
2
0
Comparing divergent model organisms
2
1
Order and disorder: Ecological adaptations not mutations
6
0
microRNAs and species relationships
3
0
Ecologically linked adapted ants and brains
2
0
Cell-type differentiation
2
0
The wrong picture of our evolution
4
0
96 fixed amino acid substitutions, not 96 genes
6
0
Alternative splicings (very technical)
2
0
Understanding the role of mutations and evolution
4
0
Pheromones and cancer
4
0
(click to enlarge)