RNA-mediated silencing (7)

By: James V. Kohl | Published on: March 27, 2022

On 3/24/22 Reversing the miRNA -5p/-3p stoichiometry reveals physiological roles and targets of miR-140 miRNAs linked quantum coherence to coherently organized biology and quantum souls via a change in the first nucleotide in miR-140.

The energy-dependent change in the first nucleotide linked Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life (4/25/20) to Functions and underlying mechanisms of miR-650 in human cancers and Identifying the oncogenic potential of gene fusions exploiting miRNAs 3/24/22

Three of the 4 articles that linked light-activated carbon fixation in cyanobacteria from microRNA-mediated protein folding chemistry across kingdoms were published on the same day (3/24/22).
Two is coincidence, three is a pattern that was linked to the origin of life ~6000 years ago via God’s separation of equal light/equal dark on Day 4 of His Creation, and to the Holy Trinity.

Many more facts that link alterations in one or more nucleotides of one or more microRNAs from the lab-based creation of SARS-CoV-2 to promotion of synthetic mRNA vaccines that block naturally occurring energy-dependent RNA interference (RNAi), fixation of amino acid substitutions, and DNA repair in specific tissues.

See: Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line” 2/25/22

See also: Functional characterization of a ‘plant-like’ HYL1 homolog in the cnidarian Nematostella vectensis 3/15/22 indicates a conserved involvement in microRNA biogenesis.

…these results suggest that the last common ancestor of animals and plants carried a HYL1 homolog that took essential part in miRNA biogenesis and indicate early emergence of the miRNA system before plants and animals separated.

If the theorists are right, my perception of microRNA-mediated cause and effect is wrong, and these facts cannot be linked to our God-given protection from virus-driven diseases across kingdoms from species of soil bacteria  to species of plants and animals via the gut bacteria of insects, mammals, and primates, including humans.
The energy of Creation might have automagically emerged from the cosmic void and led to our evolution from pond scum over billions to millions of years. If the theorists are wrong, God’s Creation of sunlight and humidity link the ATP-dependent creation of RNA and a pH-dependent change in a single nucleotide polymorphism (SNP) to the basis for former President Trump’s claim on 4/23/20 that sunlight and humidity weaken COVID19.

No experimental evidence supports the data-driven models of evolution via natural selection for beneficial mutations during billions to millions of years. For comparison, changes in microRNAs have been linked by researchers in Russia to protection from SARS-CoV-2 and to prevention of all virus-driven pathology by researchers in China, who have linked changes in microRNAs to cancers.

If the facts about how a change in one nucleotide of one microRNA cannot be linked from changes in furin cleavage to the Wuhan lab-based creation of SARS-CoV-2 and to promotion of synthetic mRNA vaccines that block naturally occurring energy-dependent RNA interference (RNAi) and DNA repair in specific tissues, my model will not be supported by more experimental evidence of top-down causation.

See: Top-down causation and emergence: some comments on mechanisms 9/29/11

Both bottom-up and top-down causation occur in the hierarchy of structure and causation.

Simply put, theorists and others like them will suffer unnecessarily and die prematurely from preventable and/or treatable virus-driven pathology because some people believe they know more than researchers who have published more than 138,000 indexed works that mention “microRNAs.
See also: From hydrogen atom transfer in DNA base pairs to ecosystems Can 47,000 indexed articles that mentioned microRNAs on 3/2/16 be linked from 137,000 on 3/12/22 to ~138,000 on 3/26/22 that refute every aspect of neo-Darwinian pseudoscientific nonsense about mutation-driven evolution across billions to millions of years? If so, more than 1000 additions per month to the PubMed database may cause me to fall behind in my reporting of biophysically constrained top-down causation across kingdoms.

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