WHO broke the breakthrough (1)

By: James V. Kohl | Published on: March 19, 2023

See first: miRNA-mediated epigenetic effects (10)

See my group’s claims in From fertilization to adult sexual behavior (1996) before more pseudoscientific nonsense is linked to more unnecessary suffering and premature deaths by theorists who learned nothing about stem cell creation and cell type differentiation — even after the WHO (the World Health Organization) broke the 2002 breakthrough: RNA interference (RNAi) into pieces of moronic theories.

Moving forward (25 years later): Vibrations in microtubules (1997) linked our claims from 1996 about the ATP-dependent Creation of RNA to prevention of all virus-driven pathology via claims about the Large-scale integration of the non-coding RNAs with DNA methylation in human cancers 3/15/23

Light-activated protein folding chemistry is the ATP-dependent requirement for biophysically constrained life that led Science Magazine to report “Small RNAs” as the 2002 Breakthrough of the Year 12/19/02, which led Nova to report that RNA is now at the heart of a scientific and medical revolution 11/15/12 (video).

That was two decades ago. Historical perspective:

At the end of a 2012 presentation on microRNAs (miRNAs) during the annual meeting of the Society for Neuroscience (SfN), I asked the speaker if everything that happened in all cell types occurred downstream from miRNAs. His affirmation of that fact can now be viewed in the context of 155,628 results from a PubMed search for the term miRNAs.

For comparison, a search for “mutations and evolution” is linked to Yeast-based evolutionary modeling of androgen receptor mutations and natural selection 12/2/22. That takes you back to our claims about biodiversity across kingdoms in From Fertilization to Adult Sexual Behavior via Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 and everything else published by intelligent serious scientists since 1996.

Simply put, claims that link evolutionary modeling to facts about natural selection for food energy-dependent pheromone-regulated genetic processes of ecological adaptations in species from yeasts to humans are no longer considered valid by anyone who is not a biologically uninformed theorist. What theorists claim is evolutionary modeling is the modeling of energy-dependent biophysically constrained viral latency and ecological adaptations.

When I mentioned that fact in this tweet from 2/21/23, the tweet made 65,249 impressions that subsequently led Elizabeth Bik to block/censor me @MicrobiomDigest. See:

Random Tweeps? http://www.hawaii.edu/PCSS/biblio/articles/1961to1999/1996-from-fertilization.html … My group published this in 1996. You have consistently failed to link the facts from quantum coherence to coherently organized biology via energy-dependent RNA interference (#RNAi) and chromosomal rearrangements.

https://twitter.com/microRNApro/status/1628167024521146371

Biologically uninformed theorists, like Elizabeth Bik consistently report claims based on simulations of natural selection, and attack those who present facts that link natural selection for energy-dependent codon optimality to Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition 10/4/16.

See also: Mechanism of epithelial-mesenchymal transition in cancer and its regulation by natural compounds 3/17/23 and the forthcoming publication of Extracellular vesicles as a potential therapeutic for age-related macular degeneration

If you find experimental evidence that links claims from the World Health Organization (WHO) to healthy longevity in the context of Elizabeth Bik’s data-driven reality, please report it to an intelligent serious scientist who can review it and place it back into the proper context of stem cell creation and cell type differentiation, which was detailed for ages 14+ in Cellulose: A Plant Cell Biology Game

Patents, held by Harvard, Pfizer, Takeda and Therapeutic Solutions can be viewed in the context of Mutations and Evolution of the SARS-CoV-2 Spike Protein 3/19/22, and Combating Evolution to Fight Disease 3/7/14. Mutations in viruses benefit the virus, not the organisms they infect. That’s why Angel Trumpets are extinct in the wild, despite all their attempts to survive via changes in light-tracking, pollination at night by moths, changes in color and changes in the fragrances they produce.

If she has not blocked you, check on Elizabeth Bik @MicrobiomDigest for any nonsense she might share that could otherwise be linked to facts about ecological adaptations via Conceptualizing microbe–plasmid communities as complex adaptive systems 2/21/23


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